All Early Career Research Content
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Adults who have survived childhood cancer are at increased risk of severe COVID-19
People who have survived cancer as children are at higher risk of developing severe COVID-19, even decades after their diagnosis. This is shown by a new study from Karolinska Institutet published in the journal The Lancet Regional Health – Europe.
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Hep E virus can live out entire life cycle in kidney cells
Scientists have succeeded in proving in cell culture that hepatitis E viruses can infect kidney cells and can multiply with their help. The entire replication cycle of the virus takes place in kidney cells in the same way as in liver cells, their study shows.
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Study advances understanding of immune system’s crucial role in phage therapy
Scientists have assessed the effectiveness of phage therapy in treating pneumonia. What they discovered about the mechanisms behind phage therapy could inform treatments in clinical settings to help patients facing similarly stubborn infections.
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Engineers develop electrochemical sensors for cheap, disposable diagnostics
Electrodes coated with DNA could enable inexpensive tests with a long shelf-life, which could detect many diseases and be deployed in the doctor’s office or at home.
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New immunotherapy strategy targets difficult-to-treat brain tumors with gut microbiota
Researchers have demonstrated a new therapeutic strategy that can enhance the efficacy of immunotherapy for brain tumors by utilizing gut microbes and their metabolites. This also opens up possibilities for developing microbiome-based immunotherapy supplements in the future.
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Seasonal allergies caused by fungal spores now start three weeks earlier under climate change
Researchers have found that, on average, spore allergy season in the US was kicking off 22 days earlier in 2022 than it had been in 2003.
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Novel flu vaccine adjuvant improves protection against influenza viruses, study finds
Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus challenges when combined with a mucosal adjuvant that enhances the body’s immune response, according to a study.
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Research suppresses coronavirus by targeting Mac1
A new study details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the “macrodomain,” found in all coronaviruses such as SARS-CoV-2 and MERS-CoV.
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With AI, researchers find increasing immune evasion in H5N1
A new analysis suggests that the H5N1 avian influenza virus is evolving clever strategies. Using artificial intelligence tools, researchers analyzed thousands of viral proteins and found that their bonds to protective antibodies have weakened over time.
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Pandora’s microbes – The battle for iron in the lungs
Newly discovered natural compounds from the little studied Pandoraea bacterium influence the lung microbiome by competing for iron.
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Tracking microbial rhythms reveals new target for treating metabolic diseases
Researchers harness the benefits of time-restricted feeding on the gut microbiome — with the ultimate goal of developing new therapies for obesity, diabetes and related diseases.
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Supercharged HIV vaccine could offer strong protection with just one dose
Researchers have shown that they can generate a strong immune response to HIV with just one vaccine dose, by adding two powerful adjuvants — materials that help stimulate the immune system.
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Gut microbiome composition and food insecurity linked to risk of cognitive impairment in adults
A new study has found a compelling link between the composition of the gut microbiome and the risk of cognitive impairment (RCI) in adults, underscoring the complex role that both biology and social determinants—such as food insecurity—play in brain health.
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Coveted lac pigment may have a fungal origin
The colourful pigment extracted from the lac insect may actually be produced by a symbiotic yeast-like organism living inside the insect, a new study has found. The yeast-like organism exclusively harbours genes coding for key ingredients in the pigment synthesis pathway.
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New research reveals how octopus uses arms to sense chemical clues from microbes
A new study reveals what the octopus is feeling when it ‘tastes’ the seafloor— biochemical information from the microbial world. The animal uses its arms to determine whether prey is safe to eat or whether unhealthy eggs should be ejected from the nest.
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New vaccine works against multiple fungal infections
A vaccine developed by University of Georgia researchers successfully protects against and treats vaginal yeast infections in mice, according to a study.
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Researchers establish link between form and function of gut bacterium
New insights into the functional differences between the various morphotypes of Bacteroides thetaiotaomicron could open up new possibilities for medicine. A better understanding of their diversity could lay the foundation for novel microbiome-based therapies.
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Mushrooms could be the key to developing better materials
Researchers are studying the cell structure of fungi to learn how it determines their mechanical properties and what science can learn from that to create better materials. They analyzed their cell structures and tested them to calculate the stress loads they could handle.
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International comparison reveals gender differences in antimicrobial resistance
A recent study analysed the DNA map of more than 14,000 gut metagenomes in a global dataset and found differences in antibiotic resistance between genders. In high-income countries, women had more antibiotic resistance genes than men.
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Machine learning method helps bring diagnostic testing out of the lab
A new point-of-care biosensing method, dubbed LOCA-PRAM, improves the accessibility of biomarker detection by eliminating the need for technical experts to perform the image analysis.