All One Health Content – Page 152
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NewsSelf-produced bacterial toxin induces cancer cells to ‘commit suicide’
Researchers have encoded a toxin produced by bacteria into mRNA (messenger RNA) molecules and delivered these particles directly to cancer cells, causing the cells to produce the toxin – which eventually killed them with a success rate of 50%.
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NewsScientists develop all-species Covid test
In an advance that will help scientists track coronavirus variants in wild and domesticated animals, researchers report they can now detect exposure to the SARS-CoV-2 virus in any animal species.
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NewsNew bacterial blueprint will help fight antibiotic resistance
Scientists have gained high-res structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it and thus suppress disease-causing bacteria.
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NewsCOVID-19 jab reduced disease disparities between low- and high-income communities
COVID-19 vaccination helped reduce disparities in disease incidence between low- and high-income communities, according to a new analysis led by Cedars-Sinai investigators.
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NewsAlarming antibiotic resistance discovered in war-torn Ukraine
Microbiologists investigating bacterial resistance among the war-wounded Ukrainian patients treated in hospitals have warned that the entire European region is under threat after finding that many were affected by bacteria that exhibited an extremely high level of antibiotic resistance.
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NewsNatural molecule added to toothpaste may help prevent plaque and cavities
Scientists have discovered that 3,3′-Diindolylmethane (DIM), a naturally occurring molecule also known as bisindole, reduces the biofilms that produce plaque and cavities by 90% and is also found to have anti-carcinogenic properties.
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NewsNew CRISPR gene editing approach opens up more of the genome
Scietnists have come up with a new way to identify diverse CRISPR RNA variants that can specifically home in on challenging areas of DNA to target for editing. The new approach opens up more of the genome for editing, enabling the repair of mutations associated with more diseases.
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NewsNearly half of TB cases in prisons worldwide go undetected
In the first global assessment of tuberculosis among incarcerated people, a new study found consistently high TB case rates and low case detection in prisons.
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NewsFuture medicines could feature ingredients targeting bacterial motility and chemotaxis
Future medicines will probably be made up of a cocktail of compounds that inhibit different bacterial targets, including some that act against their motility and chemotaxis mechanisms, a new review suggests.
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FeaturesThe pandemic potential of poxvirus infections
What can the causes of ancient pandemics, smallpox and viral evolution tell us about future threats?
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News‘Hospital pathogen’ widespread in Vietnam’s environment
A pathogen considered to be a cause of hospital infection is widespread in Vietnam, turning up in farm soil and pig faeces as well as hospital beds and toilet floor surfaces, with 70% of isolates found to be resistant to at least one class of antimicrobials.
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NewsCyanotriazole compounds can rapidly cure trypanosome infections in mice
Scientists have identified a class of cyanotriazoles (CTs), which exhibit potent trypanocidal activity and lead to rapid clearance of parasites both in vitro and in mouse models of Chagas disease and human African trypanosomiasis.
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NewsCRISPR-like system in eukaryotes can edit the human genome
The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems.
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NewsNanoparticle may improve mRNA cancer vaccines
Tests in mice with melanoma and colon cancer show the tiny particle creates an ‘army’ of immune cells that carry vaccine’s instructions, say the researchers.
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NewsFlaws in COVID-19 weather studies spark call for improved publishing practices
Research that linked the weather with the spread of COVID-19 during the pandemic was inaccurate and poorly scrutinised by fellow scientists, suggests a new study.
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NewsAI model can accelerate development of new antivirals
Researchers have shown that IBM’s AI Model, MoLFormer, can generate antiviral molecules for multiple target virus proteins, including SARS-CoV-2, that can accelerate the drug discovery process.
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NewsMicroneedle array with antibacterial nanoparticles targets acne
Researchers have designed a new microneedle patch engineered with ultrasound-responsive zinc-based metal-organic framework (MOF) antibacterial nanoparticles, promising pain-free delivery to treat bacterial infection on skin tissue and facilitate skin repair.
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NewsMolecular insights may inform new treatments for drug-resistant TB
Researchers have used state-of-the-art imaging to examine two new compounds that target ATP synthase, potentially stopping TB bacteria from producing the energy they need to survive.
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NewsDigital test directly measures HIV viral load
Researchers have developed a time and cost-efficient digital assay that can directly measure the presence of HIV in a single drop of blood.
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NewsResearchers can use ultrasound to control orientation of small particles, including bacteria
Using ultrasound technology and a nozzle, scientists have separated, controlled and ejected different particles based on their shape and various properties, with implications for drug delivery and bioprinting.