All Antibiotics articles – Page 5
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NewsProtein shuttling mechanism helps bacteria pump out antibiotics
By a joint-university effort, the mechanism of a bacterial efflux pump complex to remove molecules, including antibiotics, has been determined and the extent of bacterial toxin resistance by the complex has also been evaluated with a cutting-edge device.
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NewsAI accelerates the search for new tuberculosis drug targets
A novel biotechnology was developed to utilize artificial intelligence (AI) as a high-throughput way to identify more effective antimicrobial candidates to treat the multi-drug resistant Mycobacterium tuberculosis and understand their underlying modes of action.
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NewsJumbo phages deploying secret handshakes could usher in new antibiotics
Jumbo phages create a restricted space inside bacteria where they can copy their DNA while surrounded by a protective shield. A new study reveals that the shield works via a set of ’secret handshakes’, allowing only a specific set of useful proteins to pass through.
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NewsPersister act: Why antibiotics can fail even against non-resistant bacteria
A new study challenges the concept that persisters are the cause of antibiotic ineffectiveness, demonstrating that standard laboratory tests of antimicrobial clearance produce misleading results, giving a false impression of a small group of particularly resilient persisters.
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NewsAsthma and antibiotic use may predict nasal polyp recurrence after endoscopic sinus surgery
A recent study suggests that patients with chronic rhinosinusitis, who had undergone endoscopic sinus surgery, have a higher chance of undergoing revision sinus surgery that removes nasal polyps if they have asthma and are using antibiotics.
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NewsAntibiotics of the future are prone to bacterial resistance
Two studies have found that resistance can develop against new antibiotics even before they are widely used, compromising their effectiveness from the start. The studies focused on five critical bacterial species and examined 18 new antibiotics.
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NewsResearchers identify genetic ‘fingerprint’ to predict drug resistance in bacteria
To avoid antibiotic overuse and allow precise bacterial infection treatment, particularly against bacteria with multidrug resistance, a diagnostic tool was developed that identifies the pattern of DNA repair deficiencies acting as the bacterial antibiotic resistance ‘fingerprint’.
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NewsShorter, smarter, safer: Short-course antibiotics can revolutionize healthcare
Researchers suggest that short-course antibiotic treatment could be the next game-changing strategy to treat ventilator-associated pneumonia (VAP) in various economic settings. It provides a cost-effective and practical approach that benefits both patients and the healthcare systems.
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NewsAntibiotic treatment for drug-resistant tuberculosis found to be safe and effective in clinical trial
Two clinical trials were conducted to successfully test an oral antibiotic levofloxacin for the preventive treatment of multidrug-resistant tuberculosis (MDR-TB).
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NewsNew computer models open door to far more targeted antibiotics
A powerful computer-modelling approach has been developed to give the antibiotics a laser-like precision for targeting specific types of bacteria among specific parts of the human body.
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NewsManure management in China cuts river antibiotic pollution but raises groundwater contamination risks
A study of antibiotic pollution patterns in China’s water systems over the past decade found a 59% decrease in antibiotic pollution in rivers, primarily due to reduced direct manure discharge, but antibiotic leaching into groundwater has increased by 15%.
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NewsNew research reveals reasons for antibiotic usage in Indian chicken farming
New research exploring antibiotic use in chicken farming in eastern India reveals how poultry companies play a significant role in influencing the way antibiotics are used during food production compared to chicken farmers.
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OpinionAntimicrobials for an Antimicrobial Resistant World
The fight against AMR will require innovation, collaboration, and a fundamental shift in perspective – but it’s a fight we can win.
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NewsTuberculosis strains resistant to new drugs are transmitted between patients
Researchers have identified 514 Mycobacterium tuberculosis strains that are resistant to TB drugs, including both old and new treatment regimens, in 27 countries across four continents. 28% of these strains were transmitted directly from one patient to another.
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NewsOvercoming resistance: McMaster researchers find new utility for old antibiotics
In a recent study, researchers found that zinc plays a vital role in how some of the world’s most dangerous bacteria resist antibiotics.
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NewsExploring the impact of probiotics on gut microbiota disruption caused by antibiotics
In a new review, eight scientists comprehensively examined the evidence on using probiotics to restore the gut bacterial community during and after antibiotic treatment.
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NewsFirst full characterization of kidney microbiome unlocks potential to prevent kidney stones
Low levels of bacteria like E. coli and Lactobacillus in our urine come from communities in our kidneys, where they promote or prevent kidney stone formation.
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CareersVan Hung Vuong Le: my year as a Junior Editor with Letters in Applied Microbiology
One year into our Junior Editor training programme with Letters in Applied Microbiology, Van Hung Vuong Le from the University of Exeter reflects on the experience.
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NewsAntibiotics from bacteria could counter biotic stress in crops, replacing synthetic chemicals
Actinomycetes-derived antibiotics and other metabolites could be deployed to mitigate biotic stress in crops, potentially replacing synthetic chemicals as chemo-control agents against phytopathogens, a new review suggests.
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NewsUsing antibiotics alone to treat children with appendicitis is a cost-effective and safe alternative to surgery
An analysis of data from more than 1,000 children with uncomplicated acute appendicitis found an antibiotics-only approach resulted in less pain and fewer days off from school during the first year after the initial hospital visit.