All Antibiotics articles
-
NewsPlant phenolic acids supercharge old antibiotics against multidrug resistant E. coli
Plant derived phenolic acids can dramatically enhance the activity of existing antibiotics against multidrug resistant E. coli, offering a promising new tool in the global fight against antimicrobial resistance.
-
NewsAntibiotics could trigger immune response through gut microbiome metabolites
Researchers report how one of the most abundant gut bacteria responds to tetracyclines, a class of commonly prescribed antibiotics. Newly characterized signals released by the bacterium could aid the host’s immune response, inhibit pathogens and restructure the gut microbiome.
-
NewsResearchers rescue antibiotics from resistance using phototherapy
Researchers have used phototherapy to inhibit a protein in E. coli bacteria that makes them resistant to antibiotics. This new method, if proven safe and effective in living organisms, holds promise for rescuing the effectiveness of antibiotics that bacteria have become resistant to.
-
NewsNew study reveals how a common antibiotic disrupts nitrogen cycling and boosts greenhouse gas emissions in estuaries
Antibiotics may have far reaching impacts on wetland chemistry, according to a new study that identifies the bacteria responsible for breaking down the antibiotic sulfamethoxazole and links this process to increased emissions of nitrous oxide, a potent greenhouse gas.
-
NewsPhase 2 clinical trial results show potential to shorten TB treatment time
New clinical trial results show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as “SPaL.”
-
NewsWastewater from most countries favours non-resistant bacteria
Municipal wastewater contains a large range of excreted antibiotics and has therefore long been suspected to be a spawning ground for antibiotic-resistant bacteria. By testing the potential of untreated municipal wastewater from 47 countries to select for resistant E. coli, researchers show that while some samples indeed do so, most instead suppress them.
-
NewsEmerging pollutants threaten efficiency of wastewater treatment: New review highlights urgent research needs
A new scientific review has shed light on how emerging pollutants commonly found in wastewater are disrupting biological phosphorus removal processes, posing risks to water quality and ecological health. The study examines how pharmaceuticals, microplastics, and industrial chemicals interfere with the key microorganisms responsible for phosphorus removal in wastewater treatment plants.
-
NewsScientists find way to find the gut microbiome into a longevity factory
A team of researchers has found a way to turn the bacteria living in the digestive tracts of animals into factories that can produce compounds that promote longevity in their hosts—showing a potential new drug development strategy.
-
NewsNew editorial urges clinicians to address sex-based disparities in sepsis treatment
Standardized antibiotic dosing frequently ignores patient-level variability. A newly published editorial is calling attention to how biological sex and gender inequities contribute to suboptimal sepsis treatment, potentially compromising outcomes for women.
-
NewsNew antibiotic for drug-resistant bacteria found hiding in plain sight
Chemists have discovered a promising new antibiotic that shows activity against drug-resistant bacterial pathogens, including MRSA and VRE. Pre-methylenomycin C lactone was ‘hiding in plain sight’ — as an intermediate chemical in the natural process that produces the well-known antibiotic methylenomycin A.
-
NewsHarnessing solar energy for environmental cleanup: Iron mineral-bacterial biofilms degrade pollutants
Researchers offer a sustainable, efficient, and scalable method for addressing soil and groundwater pollution, opening new possibilities for clean-up strategies in diverse ecosystems. This process significantly enhances the degradation of antibiotics like tetracycline hydrochloride (TCH) and chloramphenicol (CPL).
-
NewsResearchers discover method to combat antibiotic treatment failure
Researchers explored ways to alter our own immune cells to help antibiotics work more effectively. They identified a small molecule that alters the body’s immune cells, forcing them to ’wake up’ dormant bacteria and make them more vulnerable to antibiotic treatment.
-
News‘Cocktails’ of common pharmaceuticals in our waterways may promote antibiotic resistance
New research has shown, for the first time, how mixtures of commonly used medications which end up in our waterways and natural environments might increase the development of antibiotic resistant bacteria.
-
NewsWHO warns of widespread resistance to common antibiotics worldwide
One in six laboratory-confirmed bacterial infections causing common infections in people worldwide in 2023 were resistant to antibiotic treatments, according to a new World Health Organization (WHO) report.
-
NewsSoil bacteria and minerals form a natural ‘battery’ that breaks down antibiotics in the dark
Researchers have unveiled a surprising new way that soil microbes can use sunlight energy. The team developed a “bio-photovoltage soil-microbe battery” that can capture, store, and release solar energy to power the breakdown of antibiotic pollutants in the dark.
-
NewsSummer studentship: Shen explores how a novel peptide can destabilise the outer membrane of E. coli
Li Shen reports back on his AMI-sponsored summer studentship which investigated a novel antibiotic adjuvant at the Centre for Bacterial Resistance Biology, Imperial College London.
-
NewsNew antibiotic targets IBD — and AI predicted how it would work before scientists could prove it
The new antibiotic, enterololin, attacks and kills only a specific group of disease-causing bugs, which includes the type of E. coli that drives Crohn’s disease. It is a promising new treatment option for people affected by Crohn’s and other IBD-related conditions.
-
NewsTwo-drug combination shows promise in helping heal chronic wounds
By adding small doses of a simple molecule called chlorate to standard antibiotics, researchers foundthe combination proved 10,000 times more effective at killing bacterial cells in the lab than single-drug antibiotics.
-
NewsStartling images show how antibiotic pierces bacteria’s armor
Researchers have shown for the first time how life-saving antibiotics called polymyxins pierce the armour of harmful bacteria. They showed how Polymyxin B rapidly caused bumps and bulges to break out on the surface of an E. coli cell, followed by the bacterium shedding its outer armour.
-
News'Know-do gap' drives inappropriate antibiotic overprescribing for child diarrhea in India
Researchers report that the persistent “know-do gap” — where clinicians know guidelines but practice differently — is the primary driver of antibiotic overprescribing for pediatric diarrhea in India’s private sector.