All Antibiotics articles
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Researchers discover method to combat antibiotic treatment failure
Researchers explored ways to alter our own immune cells to help antibiotics work more effectively. They identified a small molecule that alters the body’s immune cells, forcing them to ’wake up’ dormant bacteria and make them more vulnerable to antibiotic treatment.
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‘Cocktails’ of common pharmaceuticals in our waterways may promote antibiotic resistance
New research has shown, for the first time, how mixtures of commonly used medications which end up in our waterways and natural environments might increase the development of antibiotic resistant bacteria.
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WHO warns of widespread resistance to common antibiotics worldwide
One in six laboratory-confirmed bacterial infections causing common infections in people worldwide in 2023 were resistant to antibiotic treatments, according to a new World Health Organization (WHO) report.
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Soil bacteria and minerals form a natural ‘battery’ that breaks down antibiotics in the dark
Researchers have unveiled a surprising new way that soil microbes can use sunlight energy. The team developed a “bio-photovoltage soil-microbe battery” that can capture, store, and release solar energy to power the breakdown of antibiotic pollutants in the dark.
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Summer studentship: Shen explores how a novel peptide can destabilise the outer membrane of E. coli
Li Shen reports back on his AMI-sponsored summer studentship which investigated a novel antibiotic adjuvant at the Centre for Bacterial Resistance Biology, Imperial College London.
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New antibiotic targets IBD — and AI predicted how it would work before scientists could prove it
The new antibiotic, enterololin, attacks and kills only a specific group of disease-causing bugs, which includes the type of E. coli that drives Crohn’s disease. It is a promising new treatment option for people affected by Crohn’s and other IBD-related conditions.
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Two-drug combination shows promise in helping heal chronic wounds
By adding small doses of a simple molecule called chlorate to standard antibiotics, researchers foundthe combination proved 10,000 times more effective at killing bacterial cells in the lab than single-drug antibiotics.
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Startling images show how antibiotic pierces bacteria’s armor
Researchers have shown for the first time how life-saving antibiotics called polymyxins pierce the armour of harmful bacteria. They showed how Polymyxin B rapidly caused bumps and bulges to break out on the surface of an E. coli cell, followed by the bacterium shedding its outer armour.
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'Know-do gap' drives inappropriate antibiotic overprescribing for child diarrhea in India
Researchers report that the persistent “know-do gap” — where clinicians know guidelines but practice differently — is the primary driver of antibiotic overprescribing for pediatric diarrhea in India’s private sector.
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Yeast in gut microbiome can worsen salmonella infection
Researchers have discovered that a yeast commonly found in our gut can make infection with salmonella worse. Salmonella binds to Candida albicans and triggers a chain reaction that allows the bacteria to better invade cells lining the intestines.
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Steel sludge transformed into powerful water cleaner for antibiotic pollution
Researchers have developed an innovative way to turn steel industry waste into a low-cost material that can clean antibiotics out of water, offering a promising solution to one of today’s growing environmental challenges.
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Scientists discover powerful new antibiotic class to tackle deadly superbugs
Scientists have discovered Novltex, a new class of antibiotics with potent activity against some of the world’s most dangerous multidrug-resistant (MDR) bacteria. It targets lipid II — an essential building block of bacterial cell walls that does not mutate.
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Plant-derived compound has antimicrobial and anti-inflammatory effects against periodontal disease
Morin-based powder, extracted from guava leaves, apple peel, and figs, can be slowly released with the help of polymers and serve as an alternative to antibiotics.
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Medications leave lasting mark on the gut microbiome, even years after use
Analysing stool samples and prescription records from over 2,500 Estonian Biobank participants, researchers found that the majority of drugs studied were linked to microbiome changes, with a substantial number of them also showing long-term effects detectable years after patients stopped taking them.
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Method probing dark matter uncovers hundreds of new bacteria, and two potential antibiotics
A new approach to exploring untapped soil resources circumvents the need to grow bacteria in the lab by extracting very large DNA fragments directly from soil to piece together the genomes of previously hidden microbes, and then mines resulting genomes for bioactive molecules.
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A ‘universal’ therapy against the seasonal flu? Antibody cocktail targets virus weak spot
Researchers report that a cocktail of antibodies protected mice—including those with weakened immune systems—from nearly every strain of influenza tested, including avian and swine variants that pose pandemic threats.
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New antibiotic to fight superbug C. diff proves effective in clinical trial
As the effectiveness of antibiotics meant to fight the deadly superbug Clostridioides difficile wanes, a research team is seeing positive results of a new antibiotic on the scene – ibezapolstat – which is proving successful in fighting these infectious bacteria in clinical trials.
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One dose of antibiotic treats early syphilis as well as three doses
Researchers have found that a single injection of the antibiotic benzathine penicillin G (BPG) successfully treated early syphilis just as well as the three-injection regimen used by many clinicians. These findings from a late-stage clinical trial suggest the second and third doses of conventional BPG therapy do not provide a health benefit.
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Unlocking how bacteria bounce back after antibiotics
A groundbreaking study has uncovered how Escherichia coli (E. coli) persister bacteria survive antibiotics by protecting their genetic instructions. The work offers new hope for tackling chronic, recurring infections.
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Researchers use generative AI to design compounds that can kill drug-resistant bacteria
With help from artificial intelligence, researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).