All blood-brain barrier articles
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NewsStreptococcus suis serotype 2 collagenase-like protease promotes meningitis by increasing blood-brain barrier permeability
Streptococcus suis serotype 2 (SS2) is an emerging zoonotic pathogen that causes meningitis in humans and pigs. Researchers have investigated the role and mechanism of the SS2 Clp in promoting the passage of the bacterium across the blood-brain barrier (BBB).
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NewsResearchers use ‘brain-on-a-chip’ to revolutionize fight against deadly encephalitis viruses
A transparent chip no larger than a stick of gum is helping scientists transform the way researchers study the human brain and develop treatments for some of the world’s deadliest viruses.
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NewsIn pregnant mice with severe flu, harmful molecules can breach fetal barriers
A new study shows, for the first time, that severe flu infection in pregnant mice leads to a breakdown in placental and brain barriers, leading to the accumulation of potentially harmful molecules in the fetal brain. Fibrinogen can pass into developing fetal brains.
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NewsHeadspace invaders: How mosquito-borne viruses breach the brain’s defenses
Using a stem cell-based model of the human blood-brain barrier, researchers compared two closely related Sindbis virus strains — one brain-invading and one not — and found that small changes in viral surface proteins called glycoproteins dictate whether the virus can cross.
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NewsPrebiotics might be a factor in preventing or treating issues caused by low brain GABA
Dietary prebiotics may induce an increase in brain GABA levels through the regulation of gut microbiota, which can be a major point for reducing or even treating these occurrences of certain neurological diseases in individuals.
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NewsBartonella and babesia found in brain tissue of child with seizures
In a new case study, researchers have found Bartonella henselae, Babesia odocoilei and Babesia divergens-like MO-1 DNA in brain tissue samples from a young child with seizures and suspected Rasmussen’s encephalitis.
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NewsBacteria invade brain after implanting medical devices
Researchers have discovered that bacteria can invade the brain after a medical device is implanted, contributing to inflammation and reducing the device’s long-term effectiveness.
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NewsGround-breaking technique deploys bacterium to deliver drugs directly to the brain
A landmark study using the nasal bacteria technique promises new treatments for neurological disorders by bypassing the blood-brain barrier.
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NewsFungus ‘hacks’ natural immune system causing neurodegeneration in fruit flies
A fungus, called Beauveria bassiana, is found to manipulate the innate immunity of the fruit flies to attack their own brain cells, causing the penetration into the blood-brain barriers and eventually neurodegeneration.
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NewsRoute of entry for Semliki Forest virus into the brain revealed, yielding brain cancer treatment hope
Researchers have shown that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and binding to a specific cell type before penetrating deeper into the brain, potentially tagging the virus as an agent for treating brain cancer.
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NewsStudy says new drug shows promise in clearing HIV from brain
An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study.
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NewsStudy reveals how the chikungunya virus deploys multiple organ attack and leads to death
An international team including virologists, physicians, epidemiologists, clinicians, physicists and statisticians has discovered new mechanisms related to central nervous system infection in fatal cases of the infection
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NewsPuppeteer fungus directs ‘summiting’ of zombie flies
Scientists have uncovered the molecular and cellular underpinnings behind the ability of the parasitic fungus Entomophthora muscae’s ability to manipulate the behaviour of fruit flies.