All broadly neutralizing antibodies articles
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News
Simulation model shows potential affordability of preventative HIV therapy for infants
A type of cost-effective HIV neutralizing antibodies was evaluated to prevent the viral infection in infants during breastfeeding in high HIV prevalance countries. This treatment option is comparatively cheaper and has high clinical impacts in high HIV burden settings to achieve global elimination.
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Research identifies key antibodies for development of broadly protective norovirus vaccine
A new study identifies powerful antibodies capable of neutralizing a wide range of norovirus strains. The finding could lead to the design of broadly effective norovirus vaccine, as well as the development of new therapeutic antibodies.
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Antibody treatment prevents severe bird flu in monkeys
A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, a new study reports.
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How protective antibodies get in malaria’s way
Researcher’s structural insights help reveal weak spot in parasite’s plan of attack which could help guide vaccine design.
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Triple antibody therapy shows promise for long-lasting HIV control
A cocktail of three broadly neutralizing antibodies (bNAb) successfully suppressed virus in people living with HIV, a new study shows. Some participants showed long-term control of the virus months after antibody levels declined to low or undetectable.
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Novel vaccine concept generates immune responses that could produce multiple types of HIV broadly neutralizing antibodies
Using a combination of cutting-edge immunologic technologies, researchers have successfully stimulated animals’ immune systems to induce rare precursor B cells of a class of HIV broadly neutralizing antibodies (bNAbs). The findings, published in Nature Immunology, are an encouraging, incremental step in developing a preventive HIV vaccine. ...
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Researchers deliver boost for HIV vaccine research
Scientists have developed a comprehensive platform for HIV vaccine research capable of both preclinically validating next-step boost immunogens and providing new insights into the basic biology of the antibody response.
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Insights from patient who cleared hepatitis C could lead to vaccine
By studying individuals who spontaneously clear hepatitis C infections, a team of researchers has identified viable vaccine targets for a disease that infects 70 million worldwide with case numbers increasing every year.