All Children’s Hospital of Philadelphia articles
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A 'Trojan Horse' approach to develop new antimalarial drugs
Researchers have discovered a key process whereby malarial parasites take up a human blood cell enzyme, which could provide a new approach for antimalarial treatment.
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Most Americans favor school vaccination requirements, but support is rising for opt-out options
A new survey finds that nearly three-quarters of U.S. adults support requiring that children be vaccinated against preventable diseases such as measles, mumps, and rubella.
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Researchers launch a pioneering project to study the human virome puzzle
The research, which will explore the universe of viruses living in the human body, is fueled by a $20-million grant from the National Institutes of Health.
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Researchers find rotavirus vaccine is safe for use in NICU babies
Transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences, suggesting that giving the rotavirus vaccine to eligible infants during their hospitalization provides immune benefits that outweigh any risks.
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Study untangles how COVID-19 wreaks widespread damage in the body
A new study sheds light on the pathways that drive organ damage and death in severe COVID-19 and helps explain why survivors of the disease can experience long-term complications.
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mRNA vaccine created to prevent and treat C. difficile
The vaccine is the first mRNA vaccine against C. difficile and would be the first vaccine in general to successfully ward off the bacterial infection.
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Rotavirus vaccinations in NICU pose minimal risk, study reveals
Rotavirus vaccines do not cause significant outbreaks of the disease in neonatal intensive care units (NICUs), according to a new study.
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Researchers find no link between COVID-19 virus and development of asthma in children
Researchers have found that a SARS-COV-2 infection likely does not increase the risk of asthma development in pediatric patients.
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COVID-19 vaccine reduces long COVID in children
Researchers have found that vaccination of children provides moderate protection against long COVID. Vaccination also has a stronger effect in adolescents, who have a higher risk of developing long COVID than young children.
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COVID-19 vaccine strongly effective for children and adolescents during delta and omicron
Children and adolescents who received one of the main COVID-19 vaccines were significantly protected and showed no increased signs of cardiac complications compared to young people who were not vaccinated.
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Antibiotic resistant microbes in gut make C difficile more infectious
Scientists have found that Enterococcus – an antibiotic-resistant, opportunistic pathogen – works together with Clostridioides difficile in the human gut, reshaping and enhancing the metabolic environment in the gut so that C. difficile can thrive.