All claudin-4 articles
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NewsScientists discover how gut bacteria toxin invades colon cells to trigger cancer
A common gut bacterium, Bacteroides fragilis, drives colon tumor formation, potentially leading to colorectal cancer, by secreting a toxin that damages the lining of the colon. Researchers have now shown that the B. fragilis toxin BFT must first bind host receptor claudin-4 before it can cause damage.