All endocytic pathways articles
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NewsApilimod blocks hepatitis E virus entry by targeting PIKfyve
Hepatitis E virus (HEV) is a major cause of acute viral hepatitis, yet antiviral treatment remains largely limited to the off-label use of ribavirin. Seeking alternative treatments,scientists screened compounds that interfere with endocytic and endolysosomal pathways—the intracellular transport system used by HEV during cell entry.