The Microbiologist is once again celebrating Halloween with our annual collection.
Reading after dark is not advised.
Researchers exposed a library of over 500,000 genetically modified tuberculosis bacteria to two commonly used antibiotics. By analysing the survivors, they pinpointed genes whose disruption significantly reduced the number of surviving persisters.
A study to investigate the identity of a fungus found on a spider during filming of the BBC Winterwatch series in Northern Ireland has confirmed it as a novel species that manipulates its host by compelling it to migrate and die in exposed situations.
The ocean waters surrounding the German island of Helgoland provide an ideal setting to study spring algae blooms, a focus of research at the Max Planck Institute for Marine Microbiology since 2009.
Long-term use of systemic antibiotics to treat adolescent acne can perturb the gut microbiome, leading to altered profiles of circulating bile acids that reduce osteoblast function and bone mass accrual, researchers show.
Researchers have identified a previously unknown, natural, defense mechanism that protects cells from Pseudomonas aeruginosa infection, as revealed in a study published in Cell Reports.
Some of the world’s deadliest bacteria seek out and feed on human blood, a newly-discovered phenomenon researchers are calling “bacterial vampirism”.
For the first time, scientists have successfully extracted and analyzed DNA from ancient cheese samples found alongside the Tarim Basin mummies in China, dating back approximately 3,600 years, suggesting a new origin for kefir cheese.
Is there a way to objectively address the history of microorganisms?
To his great surprise, microbiologist Frank Maixner found himself turning his scientific skills to mummy research. He reveals what the latest techniques are revealing about ancient humans, the history of malaria and the Medici family.
Scientists have uncovered the molecular and cellular underpinnings behind the ability of the parasitic fungus Entomophthora muscae’s ability to manipulate the behaviour of fruit flies.
The pathogen of the deadliest form of the disease has been identified in mummified soft tissue belonging to members of the Florentine dynasty.
Plague may sound like a disease from the history books, but Yersinia pestis still circulates in wildlife around the world. Despite recent concern over a possible laboratory-linked death in Russia, experts stress that human cases remain rare and the infection is usually treatable when diagnosed quickly.
Cholera deaths increased by 30% in 2025, despite fewer cases being reported to the World Health Organization (WHO). In 2025, 47 countries reported 451 499 cholera cases and 7870 deaths to WHO, the highest number of annual cholera deaths reported to WHO since 1999.
A new study sheds fresh light on the long and complex history of the plague by analysing the DNA of the bacterium. Researchers reconstructed 26 genomes of Yersinia pestis from archaeological sites in Estonia, Russia, England, the Netherlands, and Switzerland.
Analyses of the carbonate deposits in the aqueduct featuring the famous Pont du Gard shed light on the water supply of the ancient city of Nîmes - and support the theory that the city was depopulated by the plague.
Plague outbreaks dating back to around 5,500 years ago documented in hunter-gatherer communities from southeast Siberia are described in a paper. The findings, based on an analysis of ancient DNA, may be the oldest known evidence of the plague and could shed light on its origins.
A new review shows that while most infections caused by the Yersinia plague bacterium can currently be treated with antibiotics, concerns about rising antimicrobial resistance mean that we need to come up with new ways to disarm the bacteria instead of killing them.
Researchers have found the first evidence of a Bronze Age plague infection in a non-human host. The scientists discovered Y. pestis DNA in a 4,000-year-old domesticated sheep from Arkaim, a fortified settlement located in the Southern Ural Mountains of present-day Russia.
Researchers have used a combination of climate data and documentary evidence to paint the most complete picture to date of the ‘perfect storm’ that led to the deaths of tens of millions of people, as well as profound demographic, economic, political, cultural and religious change.
Modern portrayals of the Black Death quickly moving across Asia, ravaging Silk Route communities, following the course of traders, have been incorrect because of centuries of misinterpretation of a rhyming fourteenth-century literary tale, experts have found.
For the first time, researchers have uncovered direct genomic evidence of the bacterium behind the Plague of Justinian — the world’s first recorded pandemic — in the Eastern Mediterranean, where the outbreak was first described nearly 1,500 years ago.
An ancient Yersinia pestis genome recovered from sheep sheds new light on a mysterious infectious disease that plagued prehistoric Eurasia for over 2000 years.
Researchers have used the platform developed for COVID-19 vaccines to create the world’s first mRNA-based vaccine against the deadly, antibiotic-resistant bacterium behind pneumonic plague.
A study of the genetic basis of plague immunity in prairie dogs has broad implications for conservation. By comparing whole-genome sequences, the authors identified genetic variants associated with survivorship.
Scientists have discovered that the evolution of a gene in the bacterium that causes bubonic plague, Yersinia pestis, may have prolonged the duration of two major pandemics. Modifying the copy number of a specific virulence gene increases the length of infection.
Evidence from 13th-century chroniclers and physicians indicates plague may have been involved in epidemics a century before the Black Death, a new study shows.
Researchers seeking to better understand the origins and movement of bubonic plague have completed a painstaking granular examination of hundreds of modern and ancient genome sequences, the largest analysis of its kind.
Ancient DNA from bones and teeth hints at a role of the plague in Stone Age population collapse. Contrary to previous beliefs, the plague may have diminished Europe’s populations long before the major plague outbreaks of the Middle Ages.
Researchers are studying Yersinia pestis, the bacterium that causes bubonic and pneumonic plague, to better understand its ability to evade the immune system and apply that understanding to control other pathogens.
Researchers have identified three 4,000-year-old British cases of Yersinia pestis, the bacteria causing the plague – the oldest evidence of the plague in Britain to date.
Mathematical modeling reveals how fleas with early-stage Yersinia pestis infections are insufficient to drive epizootic outbreaks but can help promote a low level of enzootic plague.
Bunhill Fields cemetery in the City Road is a quiet haven on the edge of the City of London, mainly attracting office workers seeking lunchtime tranquility or possibly a shortcut to the Artillery Arms pub in Bunhill Row.