All Helmholtz Institute for RNA-based Infection Research articles
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News
Novel compound inhibits the growth of tumor-associated Fusobacteria
Researchers seeking ways to eliminate fusobacteria in carcinomas have made an unexpected discovery: their control compound, FUS79, which did not target a specific transcript, exhibited strong activity against five fusobacterial strains without affecting other tested bacterial species.
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Scientists unveil novel anti-CRISPR protein mechanism
Apart from their counter-defensive function, anti-CRISPR proteins hold great promise for enabling more precise control over CRISPR technologies. Researchers have now further elucidated the function of an important yet so far uncharacterized anti-CRISPR protein.
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Decoding HIV genomic tactics in viral replication
Research on HIV-1 unravels the viral and host translational regulations during viral replications through the identification of RNA structures and previously unrecognized genetic elements - this could bring potential therapeutic interventions to counter the viral manipulations.
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Researchers uncover control mechanisms of polysaccharide utilization in gut bacterium
Polysaccharide utilization loci (PULs) complexes enable bacteria to bind, break down, and import specific polysaccharides, contributing to successful gut colonization. A new study explores how PULs are regulated post-transcriptionally to adapt to environmental changes.
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Researchers unlock gateway to open up more bacterial species for research
Researchers have introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.
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Missing puzzle piece discovered that influences sensitivity of gut bacterium to antibiotics
Scientists identify the small RNA that influences the sensitivity of the intestinal pathogen Bacteroides thetaiotaomicron to certain antibiotics.
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Scientists shine a new light on the tug-of-war between virus and host
Researchers have recently developed a new method that, for the first time, enables the discovery of interactions for specific regions within a target RNA molecule.