All hepatitis B virus articles
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NewsLong non-coding RNAs offer new hope for earlier detection and improved treatment of liver cancer linked to hepatitis B
Long non-coding RNAs may play a pivotal role in shaping the future of diagnosis, prognosis, and treatment in HBV-associated liver disease.
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NewsROS–Jak2/Stat3 signaling drives HBV-induced liver inflammation
Scientists investigated the mechanisms underlying HBV-induced liver inflammation and identified a reactive oxygen species (ROS)-dependent signaling cascade that activates the Jak2/Stat3 pathway, thereby triggering hepatic inflammatory responses.
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NewsLong-term dynamic virological response patterns and clinical outcomes in hepatitis B virus-related cirrhosis
The long-term clinical outcomes of patients with hepatitis B virus (HBV)-related cirrhosis receiving nucleos(t)ide analog (NA) therapy according to virological response patterns remain inadequately defined. A new study aimed to investigate the association between virological response patterns and clinical outcomes.
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NewsHow the immune system battles lifelong viral infections acquired at birth
Millions of people worldwide carry viral infections they acquired at birth, often for life. For a long time it was assumed that the immune system hardly fights these pathogens. Researchers show that the body’s defenses do indeed act against the virus.
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NewsCat viruses offer window into human oncogenesis
Cats are not just beloved companions; they are emerging as key “research partners” in unravelling viral cancer mechanisms. A new review explores how feline tumour viruses offer vital insights into human oncology and viral carcinogenesis from a comparative oncology perspective.
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NewsBiomarkers indicating higher liver cancer risk in chronic hepatitis B patients identified
Researchers have identified Hepatitis B RNA serum levels as a biomarker that more accurately stratifies risk of liver cancer in individuals who have been functionally cured of chronic hepatitis B.
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NewsSome acute and chronic viral infections may increase the risk of cardiovascular disease
In the weeks following a bout of influenza or COVID, the risk of heart attack or stroke may rise dramatically, and chronic infections such as HIV may increase the long-term risk of serious cardiovascular disease events, according to new, independent research.
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NewsEmerging serum biomarkers for chronic hepatitis B: Focus on serum HBV RNA and HBcrAg
There is a pressing need for non-invasive biomarkers that can accurately reflect the activity of the hepatitis B viral reservoir and predict clinical outcomes. This review synthesizes the evidence for two such promising biomarkers: serum HBV RNA and hepatitis B core-related antigen (HBcrAg).
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NewsNext-generation ‘molecular scissors’ may offer hope for chronic hepatitis B sufferers
Researchers have developed engineered precision ’molecular scissors’ that can permanently disable the genetic blueprint of the hepatitis B virus (HBV). The approach directly targets covalently closed circular DNA (cccDNA), the stubborn viral reservoir.
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NewsEpidemiology, achievements, and challenges in the elimination of hepatitis B in China
A new review outlines China’s progress towards meeting the World Health Organization (WHO) hepatitis B virus 2030 elimination targets, identifies persistent gaps, and highlights strategies for achieving HBV elimination.
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NewsHepatitis B: new rapid diagnostic test to halt mother-to-child transmission
Scientists have assessed a new rapid diagnostic test to identify pregnant women at elevated risk of transmitting hepatitis B to their babies. This diagnostic tool could help eliminate hepatitis B by preventing mother-to-child transmission during childbirth.
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NewsInterventions could eliminate transmission of hepatitis B from mothers to babies in Africa
Researchers at the University of Liverpool have conducted a large-scale analysis that sheds light on the critical steps needed to combat the vertical transmission of chronic hepatitis B virus (HBV) in Africa. Source: Solasly A baby in the womb of its mother being held by its mother and ...
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NewsHepatitis B is a problem for a growing number of patients on immunosuppressive medications
The American Gastroenterological Association (AGA) has unveiled an updated clinical practice guideline addressing the prevention and management of hepatitis B virus reactivation (HBVr) in patients on immunosuppressive drugs.
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NewsStudy reveals how dopamine inhibits the expression of hepatitis B virus surface and e antigens
A new study finds that dopamine inhibits the expression of hepatitis B virus surface and e antigens - HBsAg and HBeAg - by activating the JAK/STAT pathway and upregulating ISG15 expression.
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NewsResearchers may have found an Achilles heel for Hepatitis B
Researchers have revealed never-before-seen mechanisms that may lead to new therapeutic approaches for HBV.
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NewsResilience approach proposed for accurate diagnosis of HBV-related diseases
Chronic hepatitis B virus (HBV) infection poses a significant threat to global public health, contributing to liver-related morbidity and mortality. The current diagnostic methods for HBV-related diseases, such as laboratory tests, ultrasounds, computed tomography (CT), and liver biopsies, often overlap and consume valuable medical resources. In response to this challenge, ...