All Infection Prevention & Control articles – Page 4
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NewsMajor clinical trial provides definitive evidence of impacts of steroid treatment on severe brain infection
A major UK clinical trial has shown that adding the corticosteroid dexamethasone to standard antiviral treatment for encephalitis, caused by herpes simplex virus (HSV) does not improve long-term outcomes overall, although early use may lead to better recovery.
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NewsScientists discover novel immune ‘traffic controller’ hijacked by virus
Researchers have discovered a tissue protein that acts as a central ‘traffic controller’ for immune cells and can be hijacked by a virus to weaken immune responses. Cytomegalovirus (CMV) can hijack this system by producing a protein that blocks CD44 function on stromal cells.
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NewsMost would recommend RSV immunizations for older and pregnant people
A US survey found an increase in awareness of immunizations that are available for RSV. The survey of 1,637 U.S. adults also found that about 6 in 10 respondents would recommend the vaccine or antibody injections to the groups recommended by the CDC, an increase from past years.
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CareersThe National Collection of Pathogenic Viruses (NCPV): a critical resource for virology and public health
It’s now 25 years since the National Collection of Pathogenic Viruses (NCPV) was founded as a dedicated, secure, and relevant national virus repository for the UK. Jane Burton, Teresa Ramalho and Tilly Maybery explore how the collection has evolved - and is tackling future global health concerns.
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NewsEarly translational study supports the role of high-dose inhaled nitric oxide as a potential antimicrobial therapy
Researchers report that high-dose inhaled nitric oxide (iNO) demonstrates potential antimicrobial activity in preclinical models and is safe and feasible in early human studies, supporting further clinical investigation.
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NewsEngineered nanobodies improved respiratory defenses in preclinical study
Engineered nanobodies improved protection against multiple viruses by bolstering respiratory mucus. The bispecific design of the nanobodies works against viruses, like influenza, which can normally evade mucosal defenses.
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NewsNew study shows how light suppresses virulence in antibiotic-resistant pathogen
Researchers uncover a light-sensitive signaling cascade in Pseudomonas aeruginosa that suppresses biofilm formation and virulence, offering a potential new strategy to combat antibiotic-resistant infections.
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NewsGlobal Virus Network warns of measles resurgence
The Global Virus Network (GVN) has expressed deep concern regarding the ongoing resurgence of measles in the United States and around the globe. Measles is one of the most contagious viral diseases known and can be lethal, particularly in unvaccinated children.
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NewsHuman nasal passages defend against the common cold and help determine how sick we get
Researchers demonstrate how the cells in our noses work together to defend us from the common cold and suggest that our body’s defense to rhinovirus—not the virus itself—typically predicts whether or not we catch a cold, as well as how bad our symptoms will be.
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NewsValneva provides update on Chikungunya vaccine IXCHIQ®
Valneva SE has announced that the company has decided to voluntarily withdraw the biologics license application (BLA) and Investigational New Drug (IND) application for its chikungunya vaccine, IXCHIQ® , in the United States, following suspension of the license by the FDA.
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NewsShingles vaccine linked to slower biological aging in older adults
Shingles vaccination not only protects against the disease but may also contribute to slower biological aging in older adults, according to a new study.
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NewsResearchers discover how a respiratory bacterium obtains essential lipids from the human body and targets fat-rich tissues
A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae—responsible for atypical pneumonia and other respiratory infections—to obtain cholesterol and other essential lipids directly from the human body.
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NewsLiquorice root could be effective against upper respiratory tract infections - while protecting ‘good’ microbes
Lozenges supplemented with liquorice root extract could be an effective remedy against upper respiratory tract infections while protecting microbes that are beneficial to the body, reveals a study presented at MLS Future Forum, which is supported by Applied Microbiology International.
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NewsCommercial water dispenser machines may contain more contamination than tap water
Water dispenser machines in commercial spaces may contain higher levels of microbial contamination if they aren’t cleaned regularly compared to the tap water sources supplying them that contain residual chlorine, according to a new study.
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NewsA CRISPR fingerprint of pathogenic Candida auris fungi
Precision diagnostic platform integrating CRISPR and single molecule technology with AI enables rapid and accurate detection of drug-resistant Candida auris pathogens.
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NewsShould younger and older people receive different treatments for the same infection?
Scientists find the mechanisms young mice use to fight sepsis become disadvantageous in older age, suggesting age-specific treatments may be necessary in ongoing antibiotic resistance crisis.
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NewsA new study reveals how cholera virulence is activated
A new study provides a long-sought structural explanation of the regulatory cascade that allows Vibrio cholerae to colonize the human gut and produce the cholera toxin that causes life-threatening diarrhea.
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NewsTB and HIV treatments are not enough for a full recovery
Existing treatments control TB and HIV, but the immune system does not revert to normal, helping explain why people living with HIV remain susceptible to infections and underscoring the need for immunotherapies.
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NewsWhy don’t antibiotic-making bacteria self-destruct?
Scientists discovered a promising new antibiotic in a soil sample. The molecule, lariocidin, is produced by the microbe Paenibacillus and shows broad activity against pathogenic bacteria. Now, the researchers report how Paenibacillus avoids harm by its own antibiotic.
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NewsResearch reveals hidden diversity of E. coli driving diabetic foot infections
New research has shed light on the diversity and characteristics of E. coli strains that drive diabetic foot infections, providing the first comprehensive genomic characterisation of E. coli strains isolated directly from diabetic foot ulcers across multiple continents.