All Infection Prevention & Control articles – Page 4
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Researchers announce breakthrough in next-generation polio vaccines
Researchers have taken a major step towards producing a more affordable and lower-risk polio vaccine using virus-like particles (VLPs). These particles mimic the outer protein shell of poliovirus, but are empty inside.
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Meningococcal vaccine found to be safe and effective for infants in sub-Saharan Africa
A new global health study found a vaccine that protects against five strains of meningitis prevalent in sub-Saharan Africa is safe and effective for use in young children beginning at 9 months of age.
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Multi-dose vaccines administered in the same site boost immune response
New research suggests that receiving multiple doses of a vaccine in the same limb leads to faster antibody development, an important strategy for providing immunity as quickly as possible during a pandemic or disease outbreak.
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Intranasal herpes infection may produce neurobehavioral symptoms, study finds
A new study finds that herpes infection through the nose can lead to anxiety, motor impairment and cognitive issues. The research is the first to show that, by exploiting a cellular enzyme, the virus can produce behavioral symptoms.
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Study discovers tuberculosis genes necessary for airborne transmission
Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person’s lungs to another person’s during coughing, sneezing or talking, according to a study that offers new targets for tuberculosis therapies.
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Purified immunoglobulin F(ab′) 2 prevents lethal staphylococcal enterotoxin B intoxication in mice and rhesus monkeys
Purified F(ab′)2 fragments are an effective antidote to lethal SEB doses in mice and rhesus monkeys, and therefore might be a favorable candidate for treating patients with severe SEB intoxication, a new study suggests.
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siRNA-AGO2 complex inhibits bacterial gene translation: a novel therapeutic strategy for superbug infection
Scientists have demonstrated that exosomes can serve as delivery vehicles to introduce AGO2-loaded siRNA into the cytoplasm of bacteria, and in turn down-regulated gene expression of the mRNA that shares sequence complementarity to the siRNA.
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Eradivir announces Phase 2 human challenge study of EV25 in healthy adults infected with influenza
Eradivir, a clinical-stage small molecule immunotherapy biotech company, announced it has begun a Phase 2 challenge study with its antiviral therapeutic, EV25.
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New study links sleep debt and night shifts to increased infection risk among nurses
A new study examining the effects of sleep patterns and shift work on the immune system has found that sleep debt and night shifts increase the risk of several common infections in nurses.
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BAADesign enables the immune escaped etesevimab fully-armed against SARS-CoV-2 Omicron subvariants
BAADesign offers a powerful tool for reengineering monoclonal antibodies to combat emerging SARS-CoV-2 variants, providing a scalable solution for future pandemic preparedness, according to a new study.
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Centauri Therapeutics selects first clinical candidate for immunotherapeutic treatment of Gram-negative bacterial infections
Centauri Therapeutics Limited has announced the selection of its first clinical candidate in the ABX-01 programme. The compound is designed to target serious Gram-negative bacterial infections in the lung.
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Study: Smartwatches could end the next pandemic
Everyday smartwatches are extremely accurate in detecting viral infection long before symptoms appear — new research shows how they could help stop a pandemic before it even begins.
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Montana State scientist receives $2.8 million grant to advance Lyme disease research
Funding from the National Institutes of Health will allow a Montana State University research team to deepen explorations into a disease that is posing an increasing threat in the U.S. Lyme disease is a bacterial infection transmitted by ticks.
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Study compares indoor transmission-risk metrics for infectious diseases
A recent study delves into the complex world of assessing the transmission risk of infectious diseases in indoor spaces. Understanding how to accurately evaluate the effectiveness of non-pharmaceutical interventions (NPIs) has become crucial.
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Reactive nitrogen species dominance is key in the fight against antimicrobial resistance
The balance between two types of molecules – reactive nitrogen species (RNS) and reactive oxygen species (ROS) – plays a crucial role in tackling drug-resistant bacteria, according to a new study.
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Flu vaccine offers moderate protection against strains dominant in most European countries in 2024/2025
According to interim analysis of influenza vaccine effectiveness for the 2024/2025 season in Europe, the vaccine offered moderate protection against dominant influenza A strains, and strong protection against influenza B.
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Newly launched Enodia Therapeutics is a biotech company with a new approach for targeted protein degradation
Argobio and the Institut Pasteur have announced the launch of Enodia Therapeutics, a groundbreaking French biotech company dedicated to block and degrade disease-causing proteins for treating cancer, inflammatory diseases and viral infections.
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A new test will make it possible to detect the parasite responsible for trichomoniasis more quickly and inexpensively
A sensitive, cheap and rapid test is developed to detect the parasite, Trichomonas vaginalis, which causes one of the world’s most common sexually transmitted infections, using an innovative approach that targets highly specific molecules with short nucleic acid sequences.
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The International Space Station is overly sterile - so making it ‘dirtier’ could improve astronaut health
The International Space Station (ISS) has a much lower diversity of microbes compared to human-built environments on Earth, and the microbes that are present are mostly species carried by humans onto the ISS, suggesting that the presence of more microbes from nature could help improve human health in the space station.
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New insights into how specific gut cells respond to bacterial toxins
Researchers have characterized a specific gut cell type, BEST4/CA7+ cells, with the ability to interact with immune cytokine interferon-γ (IFNγ), and its regulation in cellular electrolyte and water balance, in response to bacterial toxins.