All Infection Prevention & Control articles – Page 4
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Clinical trial underway for potential Long COVID treatment
A clinical trial is underway to assess the effectiveness and safety of sipavibart, AstraZeneca’s long-acting monoclonal antibody designed to provide protection against Covid-19, as a potential treatment for Long Covid.
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Topical gel relieved ear infections in animals after just one dose
Researchers report a topical antibiotic gel that, applied once, cured middle ear infection within 24 hours in chinchillas. a single dose of treatment for middle ear infections could improve patient compliance and potentially reduce pediatric antibiotic usage.
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Barriers remain to peptide-based therapies - but there are answers, reveals study
Peptide-based therapies offer the potential to transform how we treat a range of conditions - but have yet to be adopted for widespread clinical use. A new review uncovers the barriers to adoption and identifies ways to overcome these limitations.
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Monoclonal antibody nirsevimab provides strong protection against severe RSV in infants
Nirsevimab, a monoclonal antibody, is highly effective in real-world conditions at preventing severe respiratory syncytial virus (RSV) infections in infants, suggests a meta-analysis.
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Long COVID biomarkers found – associated with respiratory problems
Researchers have identified biomarkers in the blood associated with symptoms of long COVID, particularly severe respiratory disorders. The discovery can pave the way for future diagnosis and treatment.
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siRNA plus nanovaccine yields stable functional cure for chronic hepatitis B
Researchers have developed an innovative therapy for chronic hepatitis B, synergistically combining their proprietary ferritin nanoparticle-preS1 (Ferritin-NP-preS1) therapeutic vaccine with a preclinically validated HBV-specific siRNA.
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Broader antibiotic use could change the course of cholera outbreaks, research suggests
Disease modeling research suggests that, for some cholera outbreaks, prescribing antibiotics more aggressively could slow or stop the spread of the disease and even reduce the likelihood of antibiotic resistance.
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A hidden control center: How bacteria regulate their attack strategies
Researchers have discovered that a key bacterial protein, CsrA, gathers in a droplet-like structure inside cells to control when and how bacteria activate their disease-causing genes.
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Now is the time to strengthen infection prevention and control (IPC) programs in healthcare facilities
A joint position paper urges United States healthcare facilities to elevate the standards and effectiveness of their Infection Prevention and Control (IPC) programs.
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Measles may be making a comeback in the US, research finds
If immunization rates drop further over a prolonged period of time, measles and even other wiped-out diseases — such as rubella and polio — could one day make a comeback in the United States, according to a new study.
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Influenza virus hacks cell’s internal system
The influenza virus manipulates the body’s gene regulation system to accelerate its own spread, according to researchers. Their study shows that an already approved drug could help strengthen immune defenses—though its effect in humans remains to be confirmed.
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Antibiotic resistance: Towards drugs to disarm bacteria
Researchers have identified the mutation frequency decline (Mfd) protein, a virulence factor produced by all bacteria and essential for them to resist the host immune system. This protein has the additional function of promoting spontaneous and random mutations.
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European Immunization Week 2025: Inequalities in immunisation against measles could contribute to outbreaks
Research reveals inequalities in MMR vaccination that may contribute to measles outbreaks and epidemics, emphasising the importance of socioeconomic and demographic data in driving public health efforts.
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Updated recommendations to prevent infections through effective sterilization and high-level disinfection of reusable medical devices
New comprehensive guidance has been released in the US to help healthcare facilities prevent the transmission of infections through improved practices in sterilization and high-level disinfection (HLD) of reusable medical devices.
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Hospital-based outbreak detection system saves lives
An infectious diseases detection platform has proved over a two-year trial that it stops outbreaks, saves lives and cuts costs. The results make the case for adoption in hospitals nationwide and the development of a national early outbreak detection database.
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Global study finds single-dose baloxavir reduces household influenza transmission
A landmark study reveals that a single oral dose of baloxavir marboxil (baloxavir) significantly reduces the transmission of influenza within households, marking a major advancement in influenza management.
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Transatlantic collaboration to develop therapeutic for Crimean-Congo Hemorrhagic Fever
A new transatlantic collaboration will look to develop an affordable and accessible monoclonal antibody therapeutic for Crimean-Congo Hemorrhagic Fever Virus (CCHFV), which could treat and protect thousands of people globally.
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Antibiotic-resistant Escherichia albertii on the rise in Bangladeshi chicken shops
Researchers have detected alarming rates of Escherichia albertii in retail chicken meat in Bangladesh. Their findings show extensive contamination and significant antimicrobial resistance, underscoring the potential risks to public health.
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The very first structural images of a tuberculosis-fighting virus
Scientists have used advanced imaging techniques to provide a detailed look at how a tiny virus, known as a phage, invades Mycobacteria. The research could pave the way toward phage-based treatments for antibiotic-resistant mycobacteria.
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A cocktail of drugs may work against a whole family of viruses
Enteroviruses cause everything from polio to meningitis. An effective treatment could help reduce the risk of this global health problem.