All Infectious Disease articles – Page 10
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Insights from patient who cleared hepatitis C could lead to vaccine
By studying individuals who spontaneously clear hepatitis C infections, a team of researchers has identified viable vaccine targets for a disease that infects 70 million worldwide with case numbers increasing every year.
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Breakthrough antibiotic shows promise against obstinate mycobacterial infections
Researchers assemble a new antibiotic candidate, COE-PNH2, offering a more effective therapeutic option against hard-to-treat mycobacterial lung diseases.
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Researchers uncover key biomolecule involved in whooping cough infection
Researchers have identified a new complex-carbohydrate biomolecule, or glycan, that plays a key role in the nasal colonization of the Bordetella bacteria responsible for whooping cough.
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Cancer therapies show promise in combating tuberculosis
A study has identified a combination of medications that may improve blood flow within granulomas, tight clusters of white blood cells formed by the body’s immune system in response to tuberculosis infection, benefiting drug delivery.
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Candida albicans toxin plays a special role in the colonization of the digestive tract
Comparative studies on mice with a complete microbiome and a microbiome reduced by antibiotics now show that the previous assumption that the yeast form of Candida albicans is better suited for colonization needs to be revised.
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New vaccine against a highly fatal tropical disease – and potential bioterror weapon – demonstrates efficacy in animal studies
In a mouse study, researchers tested a vaccine against the bacterium that causes melioidosis and found it was highly protective against the disease, which is endemic in many tropical areas.
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Scientists close in on TB blood test which could detect millions of silent spreaders
Scientists have taken a major step towards developing a blood test that could identify millions of people who spread tuberculosis unknowingly.
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New classification of tuberculosis supports efforts to eliminate the disease
A new way to classify tuberculosis (TB) that aims to improve focus on the early stages of the disease has been presented by an international team.
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Researchers ask if active screening for tuberculosis among vulnerable populations is cost-effective
Scientists present the findings of their systematic review on active pulmonary TB screening programmes run between 2008 and 2023 in so-called high-risk groups living in low TB incidence countries.
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For each 10% increase of certain bacteria type in the gut microbiome, the risk of hospitalisation for infections falls by up to a quarter
A study of two large European patient cohorts has found that for every 10% increase in butyrate-producing bacteria in a patient’s gut, the risk of hospitalisation for any infection falls by between 14 and 25% across two large national cohorts. The
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Researchers invent artificial intelligence model to design new superbug-fighting antibiotics
Researchers have invented a new generative artificial intelligence model which can design billions of new antibiotic molecules that are inexpensive and easy to build in the laboratory.
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New blood test cuts infection diagnosis time from months to hours
Researchers have designed a platform to perform blood-based diagnoses of nontuberculosis mycobacteria, simplifying and shortening a long-complicated procedure from 6 months to 2 hours.
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Study maps main genes involved in immune response to infection by dengue virus
Researchers compared data for the immune response induced by natural infection and vaccines. They identified the key factors in the development of long-lasting immunity.
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Experts warn climate change will fuel spread of infectious diseases
A team of infectious diseases experts called for more awareness and preparedness in the medical field to deal with the impact of climate change on the spread of diseases. Their article, published in JAMA, raises the alarm about the emergence and spread of harmful pathogens. The authors ...
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Rapid specific detection of oral pathogens using CRISPR-based diagnostics
A study aiming to develop a low-cost, rapid detection technique for the widescale detection and screening of oral microorganisms suitable for point-of-care settings was presented at the 102nd General Session of the IADR.
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IVI starts technology transfer to Biological E. Limited to manufacture oral cholera vaccine for India and global markets
The International Vaccine Institute (IVI) has announced that it has commenced a technology transfer of simplified Oral Cholera Vaccine (OCV-S) to Biological E. Limited (BE), a leading India-based vaccines and pharmaceutical company.
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Insights into release of fungal toxin promise progress in treating infections
The toxin Candidalysin of the yeast Candida albicans is incorporated into an unusual protein structure during an infection, and researchers have now succeeded in deciphering the function of this unusual arrangement.
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Newly identified yeast could prevent fungal infections by outcompeting rivals, study suggests
Researchers have identified a yeast that could be used to prevent invasive candidiasis, a major cause of death in hospitalized and immunocompromised patients.
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Researchers uncover how viruses choose whether to become nasty or not
Researchers have deciphered a novel complex decision-making process that helps viruses choose to turn nasty or stay friendly to their bacterial host.
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The SNF Institute for Global Infectious Disease Research announces new advisory board
The Stavros Niarchos Foundation Institute for Global Infectious Disease Research at Rockefeller University (SNFiRU) has capped a successful first year with the establishment of a new advisory board.