All Infectious Disease articles – Page 8
-
NewsStrategic advancement of second-generation fungal vaccine VXV-01 through Phase 1 trials
The Lundquist Institute (TLI) and its start-up company Vitalex Biosciences (Vitalex) have announced that the second-generation fungal vaccine candidate known as VXV‑01 is poised to move forward in development up to and including Phase 1 clinical evaluation.
-
NewsA testing paradox for sexually transmitted infections
Surveillance evidence shows an increase in people infected with other STIs after initiating PrEP. A new study provides a counterintuitive explanation revealing a testing paradox: even when the observed cases increase, the true numbers of STIs can decrease.
-
NewsModulating key interaction prevents virus from entering cells
Researchers have found a way to modulate a common virus protein to prevent viruses from entering cells where it can cause illness. They were able to find and block an important interaction at the molecular level that allows the herpes virus to enter cells.
-
NewsImmune system keeps mucosal fungi in check
Researchers investigating the mechanisms that keep the fungus under control on our mucosa shed light on how homeostasis is maintained through the fine-tuned interplay between Candida albicans and the epithelial barrier on the one hand, and the immune system on the other hand.
-
NewsStreptococcus suis serotype 2 collagenase-like protease promotes meningitis by increasing blood-brain barrier permeability
Streptococcus suis serotype 2 (SS2) is an emerging zoonotic pathogen that causes meningitis in humans and pigs. Researchers have investigated the role and mechanism of the SS2 Clp in promoting the passage of the bacterium across the blood-brain barrier (BBB).
-
NewsStudy links gut bacteria to bloodstream infections in newborns within sub-Saharan Africa for the first time
New research has shown gut and bloodstream infections are caused by the same bacteria giving hope of better prevention and diagnosis of deadly neonatal sepsis.
-
NewsCould hidden infections be fueling long COVID?
For millions suffering from long COVID, their persistent breathlessness, brain fog and fatigue remain a maddening mystery, but microbiologists think they may have cracked the case. The review argues that co-infections acquired before or during COVID could cause symptoms to persist indefinitely for many people.
-
NewsApplications of AI in antimicrobial resistance prevention and control
Researchers have published a review shedding light on how AI is revolutionizing the prevention and control of AMR. The article illustrates how machine learning and deep learning are transforming surveillance, diagnosis, treatment optimization, and drug discovery.
-
NewsPersistent antibiotic resistance of cholera-causing bacteria in Africa revealed
In 2024, representatives from 14 African countries came together for a five-day intensive workshop on a whole-genome sequencing method called Oxford Nanopore Technology (ONT) aimed at strengthening cholera surveillance capabilities across the continent.
-
NewsGlobal Virus Network announces appointment of new board members
The Global Virus Network (GVN), a worldwide coalition of leading human and animal virologists, has announced the appointment of eight distinguished leaders to its Board of Directors.
-
NewsUnique bond identified as key to viral infection speed
Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, but new research reveals a deliberate imbalance in their shape that helps them infect their hosts.
-
NewsResearchers discover how Ebola and Marburg disrupt the gastrointestinal tract
A new study sheds light on the mechanisms behind the damage caused by Ebola (EBOV) and Marburg virus (MARV) to the gastrointenstinal tract. TIt found that both viruses are capable of infecting and replicating within human gut epithelial cells and that the viruses interfere with the cells’ ability to regulate fluid secretion, mirroring the severe symptoms observed in patients.
-
NewsPandemic ‘beneath the surface’ has been quietly wiping out sea urchins around the world
Over the last four years, an unrecognized pandemic that has been wiping out sea urchins around the world has hit the Canary Islands. The consequences on marine ecosystems aren’t yet fully known, but likely profound.
-
NewsStudy shows why mRNA-based COVID-19 vaccines can cause myocarditis
Investigators have unearthed the biological process by which mRNA-based vaccines for COVID-19 can cause heart damage in some young men and adolescents — and they’ve shown a possible route to reducing its likelihood.
-
NewsOlder age, chronic kidney disease and cerebrovascular disease linked with increased risk for paralysis and death after West Nile virus infection
Older people with a history of chronic kidney disease or conditions affecting blood flow to the brain such as stroke face about double the risk for developing neuroinvasive disease that can lead to paralysis and death following infection with West Nile virus, new research finds.
-
NewsIn pneumonia’s tug-of-war, lung microbiome could tip the balance
Scientists have found the lungs’ own microbial community, or microbiome, appears to influence how pneumonia evolves, who responds well to treatment and whether a patient will recover successfully or continue to deteriorate.
-
NewsNew 15-minute hepatitis C test paves the way for same-day treatment
Scientists have developed the fastest test yet for diagnosing hepatitis C virus (HCV). The highly accurate diagnostic delivers results to patients in just 15 minutes - crucial for kickstarting patients’ treatment before they leave their appointment.
-
NewsOpioid use linked to higher risk of C. difficile infection
New research from the University of Georgia suggests that opioid use could make patients more vulnerable to infections. The meta-analysis examined four studies of almost 120,000 patients. The researchers found that about 31% of patients who were prescribed and taking opioids caught C. diff, compared to 17% of patients who weren’t using them.
-
NewsStudy reveals promising gut-targeted therapy for C. difficile infections
Researchers have uncovered how the body’s bile acids bind to block C. diff’s most dangerous toxin. The research has informed the development of a new compound that can protect against C. diff in preclinical models, offering hope for safer, more effective treatments.
-
NewsHuman ‘mini-noses’ help understand why RSV infections are more severe in children than in adults
Why does RSV affect babies more severely? To better understand the cellular reasons behind this age-related difference, researchers compared infant and adult human nose organoids, also called mini-noses, regarding their susceptibility and response to infection.