All Infectious Disease articles – Page 8
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NewsAgricultural azoles drive clinical azole resistance in Candida tropicalis via inducing aneuploidy
To define the causal role of agricultural azole fungicides in driving clinical azole resistance in the major human opportunistic fungal pathogen Candida tropicalis, researchers conducted a systematic study integrating experimental evolution, genomic characterization, and transcriptomic profiling.
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NewsMpox study reveals hidden infections may fuel spread
A study shows that in mid- to late 2024, mpox was far more common among men who have sex with men than previously thought. Individuals without symptoms accounted for most infections and likely played a prominent role in transmission, contrary to prior assumptions that people had to be symptomatic to spread the disease.
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NewsTargeted therapeutics show promise in fighting off drug-resistant bacteria
A new study shows that when under attack, the body’s immune cells activate a cellular process called ‘mitochondrial fission’ to kill invading bacteria. Researchers found an experimental treatment called an HDAC6 inhibitor can re-activate the mitochondrial fission process in immune cells to fight invading bacteria.
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NewsImmune system overreaction linked to deadly flu in pregnancy
Researchers have discovered why influenza can lead to life-threatening complications during pregnancy. In most people, influenza stays in the upper respiratory tract and clears without spreading further. But during pregnancy, the virus can extend into the cardiovascular system, increasing the risk of severe complications for mothers and babies.
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NewsResearchers link human molecular, microbial diversity with geography, ethnicity
Researchers at the Stanford School of Medicine have found that ethnicity and geography may influence human molecular makeup — from metabolism and immunity to gut microbiota and biological aging. The findings, which published in Cell on May 14, illuminate the complex interplay between genetics and the environment, ...
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NewsReview highlights antimicrobial peptides as cross-seeding modulators at the neurodegenerative–infectious interface
In a comprehensive review, researchers synthesize emerging evidence that antimicrobial peptides and disease-related amyloids can influence one another through heterotypic cross-seeding interactions.
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NewsAI and supercomputer simulations reveal how a bacterial energy-converting enzyme pumps sodium ions
The Na+-NQR enzyme is vital for energy production in pathogenic bacteria, making it a highly promising target for new antibiotics. Researchers combined modified artificial intelligence techniques with extensive supercomputer simulations to visualize the hidden, dynamic movements of this enzyme during sodium transport.
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NewsUnderstanding and exploiting tuberculosis superspreading
A new perspective piece introduces the idea of “superspreading niches”, specific parts of community contact networks where highly infectious individuals intersect with highly susceptible contacts, as a key framework for understanding TB superspreading and designing new TB control interventions.
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NewsImplantable living materials autonomously deliver therapeutics using contained engineered bacteria
Researchers have introduced an implantable “living material” that contains bacteria that sense infections. It can release these therapeutic molecules on demand, while keeping them physically separated from the surrounding tissue.
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NewsResearchers develop experimentally validated AI model to predict the virulence of tomato yellow leaf curl virus
A research team has developed DeepTYLCV, an accurate and interpretable artificial intelligence model for predicting the virulence of Tomato Yellow Leaf Curl Virus (TYLCV). DeepTYLCV uses viral genome-derived sequence information, enabling the model to identify mild and severe strains before symptom-based confirmation.
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NewsNew report charts path for climate-disease preparedness
Changing patterns of temperature and precipitation, along with sea level rise and more extreme weather events, are impacting the ecology, evolution, distribution and prevalence of infectious disease reservoirs, hosts, vectors and pathogens. As a result, new diseases are emerging, and others are reappearing in regions where they were once uncommon.
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NewsWhy babies are dying and how we can stop it
A study has identified that the vast majority of neonatal deaths caused by infections in South Africa and other low-and-middle-income countries could be prevented through improved clinical care and targeted medical interventions.
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NewsMeasuring SARS-CoV-2 diversity in wastewater improves disease surveillance
Tracking the genetic diversity of SARS-CoV-2 in wastewater, rather than just viral abundance, dramatically improves the ability to monitor and predict COVID-19 outbreaks, researchers report.
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NewsInfluenza virus platforms: New hope for vaccines and cancer immunotherapy
Influenza virus is now being engineered to carry foreign genes and reduce virulence, serving not only for next-generation influenza vaccines but also as delivery vectors for heterologous antigens against other infections and cancers, supported by its ability to trigger robust mucosal and systemic immune responses.
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NewsIgG fucosylation linked to severe COVID-19 progression and traditional Chinese medicine therapy
A new study has uncovered that immunoglobulin G (IgG) fucosylation, a critical type of protein glycosylation, is closely associated with the progression of severe COVID-19, offering new insights into disease pathogenesis and potential therapeutic strategies.
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NewsTraditional dengue alerts are missing the mark as Vietnam’s climate shifts—researchers propose a one health solution
For decades, Vietnam’s dengue surveillance relied on a straightforward logic: when cases exceed the five-year average by a sufficient margin, sound the alarm. That logic is now breaking down.
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NewsStudy quantifies the staggering economic toll of TB
Researchers have found that TB wipes out an estimated 0.8 per cent of the world’s total economic potential every year. Losses are concentrated overwhelmingly in low- and middle-income countries, especially in South Asia and sub-Saharan Africa.
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NewsResearchers find increased bacteria infection in patients with chronic lung disease
A new study has found that people with bronchiectasis and chronic sinus disease were more likely to have mucus samples that tested positive for Pseudomonas aeruginosa. It suggests that doctors caring for patients with bronchiectasis may need to pay closer attention to sinus disease and bacterial testing.
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NewsDiseases can spread between apartments via shared ventilation, study shows
Airborne diseases like measles, influenza and COVID-19 can easily spread between units in multi-family buildings via a type of bathroom ventilation system commonly used around the world, new research suggests.