All Infectious Disease articles – Page 4
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Mucosal vaccine shows transient action against Covid-19 variant
Mucosal adenovirus vaccine Ad5-XBB.1.5 boosting elicits nasal IgA and transiently prevents JN.1 wave infection for less than 6 months in real-world settings, a new study reveals.
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Risk of deadly diarrheal diseases in children set to worsen as climate changes
Diarrhoea remains one of the most serious health threats to young children in the Global South, and new research shows that climate change is set to worsen the risk substantially.
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Antiviral treatment fails to slow early-stage Alzheimer’s
A clinical trial has found that a common antiviral for herpes simplex infections, valacyclovir, does not change the course of the disease for patients in the early stages of Alzheimer’s.
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A non-invasive test enables accurate detection of infant meningitis
A high-resolution ultrasound device has shown great accuracy in detecting suspected meningitis in newborns and infants, potentially offering a non-invasive alternative to lumbar puncture, the traditional diagnostic method.
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New genomic study reveals key drivers of strangles transmission in UK horses
A novel study has revealed new insights into how the highly contagious disease strangles spreads amongst horses in the UK. It marks a significant step forward in understanding how to more effectively manage and prevent outbreaks of this devastating equine disease.
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Pioneering research reveals worldwide scale of Hepatitis C among babies and children
A new study has estimated for the first time the number of children born globally with hepatitis C virus. Each year around 74,000 children globally are born with hepatitis C virus (HCV), with around 23,000 of these estimated to still have HCV infection at age five.
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Kākāpō decline reveals threat of parasite coextinction
Researchers have discovered that more than 80 per cent of parasites detected in kākāpō poo prior to the 1990s are no longer present in contemporary populations. They used ancient DNA and microscopic techniques to sample faeces dating back more than 1500 years.
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AI poised to revolutionize Lyme disease testing and treatment
Researchers unveiled a blood test developed with the help of artificial intelligence (AI) that identifies Lyme disease sooner and more accurately than the current standard — and that could translate to vastly improved patient outcomes.
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New study unlocks molecular defense against devastating potato pathogen
A team of plant scientists has made a significant breakthrough in understanding how potato plants defend themselves against a soilborne pathogen that causes powdery scab, an emerging and economically damaging disease affecting potato crops worldwide.
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Repurposing an abandoned drug may help treat a neglected parasitic infection
Researchers have mapped the human metabolic pathways that Cryptosporidium, an intestinal parasite, requires to survive. Shutting down these pathways may offer a new way to treat patients while avoiding the development of drug resistance.
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Bird-to-human jump by trichomonas parasites illuminated in new study
A new study reveals how genetic changes in the parasite responsible for one of the world’s most common sexually transmitted infections may have helped it adapt to human hosts.
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Scientists uncover critical role of membrane protein topology in beta-coronaviruses assembly
Beta-coronaviruses, including SARS-CoV-2, have caused global health problems. How the virus infects host cells and triggers immunological responses has been investigated extensively. However, how the virus replicates and assembles in the cell is largely unknown. Researchers at the Institute of Biophysics, Chinese Academy of Sciences, have uncovered a conserved mechanism ...
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Therapeutic vaccine for chronic hepatitis B enters first clinical trial in patients
TherVacB, a novel therapeutic vaccine for chronic hepatitis B, has entered its first clinical trial in patients. A successful phase 1a trial in healthy volunteers saw the vaccine demonstrate a favorable safety profile and trigger the desired immune responses.
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High-efficacy adjuvanted subunit vaccine against variant infectious bursal disease virus in chicks
Infectious bursal disease (IBD) is an acute, highly contagious disease caused by the infectious bursal disease virus (IBDV), primarily affecting chicks. Notably, the emergence of new mutant strains that exacerbate the disease can cause serious economic losses to the global poultry industry. To date, there is no commercial vaccine against ...
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Study of water bodies frequented by wild birds reveals presence of antimicrobial resistance genes in nine in 10 samples
The first UK study to monitor antimicrobial resistance and influenza viruses in water bodies has revealed that 92% of samples contained genes for resistance to colistin, an antibiotic of last resort.
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New study in Ukraine indicates significant lifetime exposure and ongoing transmission of hepatitis B and C viruses among the general population
A nationwide study in Ukraine has found evidence of significant exposure to hepatitis B and C viruses and substantial ongoing circulation among the population, highlighting need for immunisation and regular screening.
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Immunity to seasonal flu protects against severe illness from bird flu in ferrets
A study in ferrets — which have remarkably similar respiratory systems to humans — suggests that widespread immunity to H1N1 seasonal influenza virus may explain why exposure to H5N1 bird flu causes only mild symptoms in humans.
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Stealth genetic switch in mosquitoes halts malaria spread
Biologists have created a CRISPR-based gene-editing system that changes a single molecule within mosquitoes, stopping the malaria-parasite transmission process. Genetically altered mosquitoes are still able to bite those with malaria, but the parasites can no longer be spread to other people.
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New study brings vaccine hopes for deadly Nipah virus
Researchers have tested experimental Nipah vaccines in pigs, aiming to cut off the virus at one of its key transmission routes. The study describes the development of three vaccine candidates using different viral surface proteins.
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Research reveals STIs during pregnancy linked to adverse birth complications
Common sexually transmitted infections during pregnancy have been linked to a higher risk of significant birth complications including preterm birth, stillbirth and babies born smaller than expected.