All Infectious Disease articles – Page 2
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Researchers discover all-new antifungal drug candidate in university greenhouse
A research team at McMaster University has discovered a new drug class that could someday lead to breakthrough treatments for dangerous fungal infections. The new molecules, dubbed coniotins, were isolated from a plant-dwelling fungus called Coniochaeta hoffmannii — the samples of which were collected from the McMaster ...
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Researchers identify a potential biomarker for long COVID
Researchers have identified a potential biomarker for long COVID. The study results detail the detection of SARS-CoV-2 protein fragments within extracellular vesicles (EVs) — tiny, naturally occurring packages that help cells share proteins, metabolites, and other materials.
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Global Virus Network reaffirms support for mRNA vaccines and collaborative vaccine research
The Global Virus Network (GVN) has announced that it is unequivocally committed to the continued development and deployment of mRNA vaccines and the global scientific collaboration that makes such innovation possible.
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Malaria vaccine mimics natural immunity with high precision
A detailed analysis reveals one of the reasons why the R21/Matrix-M malaria vaccine works so well: the antibodies generated following vaccination are indistinguishable from those found in people who have been infected by the parasites.
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Lab-made sugar-coated particle blocks Covid-19 infection — Possible new treatment on the horizon
Groundbreaking research has revealed a synthetic glycosystem — a sugar-coated polymer nanoparticle — that can block Covid-19 from infecting human cells, reducing infection rates by nearly 99%.
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Chemical trick could turn losing malaria drug into a winner
A new generation of malaria drugs failed clinical trials, in part because they were hard to swallow. Chemists have remodeled their structures to make them more soluble, while maintaining their effectiveness against drug-resistant parasites.
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4,000-year-old sheep reveals that livestock played a role in prehistoric plague infections
An ancient Yersinia pestis genome recovered from sheep sheds new light on a mysterious infectious disease that plagued prehistoric Eurasia for over 2000 years.
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Fighting infections with the power of the microbiome
Scientists have discovered that bacteria of the species Klebsiella oxytoca can displace pathogenic bacteria from the gut and want to develop a living biotherapeutic based on this finding. The DZIF is now providing 2.2 million euros in funding for product development.
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Early challenges to the immune system disrupt oral health
Researchers identified changes over time in the oral microbiome of children living with HIV, offering insights into how early immune challenges shape not only oral health but also systemic health.
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Kenya achieves elimination of human African trypanosomiasis as a public health problem
The World Health Organization (WHO) has validated Kenya as having eliminated human African trypanosomiasis (HAT) or sleeping sickness as a public health problem, making it the tenth country to reach this important milestone.
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New network to address malaria among school-aged children in sub-Saharan Africa
A new network aims to improve malaria prevention among school-aged children in sub-Saharan Africa. The new partnership will unite researchers, policymakers, healthcare practitioners and other stakeholders across multiple countries to better understand and address the burden of malaria in children.
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Novel immunologic surveillance study provides new insights into post-pandemic return of respiratory viruses
Non-pharmaceutical interventions such as masking and distancing targeted towards SARS-CoV-2 during the pandemic also decreased circulation rates of and population immunity to common respiratory pathogens in children, a new study shows.
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National study urges expanded vaccine screening in emergency departments
About 49% of people are unaware of one or more vaccines recommended for them. Further, 86% have not received one or more of these vaccines, according to the first national comprehensive vaccine surveillance study conducted in emergency departments.
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Revealed: New vaccine target to block malaria transmission
Researchers have visualised a key protein complex in malaria parasites for the first time, uncovering a new target for next-generation vaccines that could help stop the disease from spreading.
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Scientists home in for a close look at lung infections
A new study has meticulously sampled different lung regions in people with cystic fibrosis to understand why infections persist after new treatments.
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Disarming a hidden killer: Predicting – and preventing – C. diff before it strikes
Researchers have developed a powerful, personalized modeling framework to predict whether Clostridioides difficile is likely to colonize an individual’s gut, and to test whether specific probiotic therapies might prevent and/or reverse that colonization.
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M42 announces breakthrough results for its AI-powered tuberculosis screening
A new study is among the largest real-world clinical validations of an AI-driven healthcare solution to date, analyzing over one million chest X-rays (CXRs) to evaluate the efficacy and scalability of AI in TB screening.
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New drug combo outperforms Tamiflu in fighting flu (and chocolate is the key)
Scientists have unveiled a new drug pairing - including a compound found in chocolate - that outperforms Tamiflu, the most widely used anti-influenza medication, against even the deadliest flu strains, including avian and swine flu.
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Study finds gaps in evidence for air cleaning technologies designed to prevent respiratory infections
A new study finds that although many technologies claim to clean indoor air and prevent the spread of viruses like COVID-19 and the flu, most have not been tested on people and their potential risks are not yet fully understood.
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Researchers debunk long-standing concern about flu treatment in children
Researchers have debunked a long-standing theory about oseltamivir, known as Tamiflu. Oseltamivir treatment during flu episodes was associated with a reduced risk of serious neuropsychiatric events, such as seizures, altered mental status and hallucination.