All Infectious Disease articles – Page 3
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Clinical study shows that nasal spray containing azelastine reduces risk of coronavirus infection by two-thirds
In addition to showing a marked reduction in coronavirus infections, the azelastine group also displayed fewer symptomatic SARS-CoV-2 infections, a lower overall number of confirmed respiratory infections, and, unexpectedly, a reduced incidence of rhinovirus infections, another major cause of respiratory illness.
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Less is more: Gene loss drives adaptive evolution of a pandemic bacterium
A study reveals a surprising evolutionary insight: sometimes, losing genes rather than gaining them can help bacterial pathogens survive and thrive. The research focused on Vibrio parahaemolyticus, a bacterium behind many of the seafood-related infections worldwide.
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Therapeutic vaccination against HPV-related tumors: Nanoparticles make the difference
Researchers have developed a therapeutic vaccination concept that can mobilize the immune system to target cancer cells. Virus peptides coupled to silica nanoparticles can elicit effective T-cell responses against HPV-related tumors. In a mouse model, the nanoparticle-based vaccine was able to partially or completely suppress HPV-related tumors.
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One shot of RSV vaccine effective against hospitalization in older adults for two seasons
One shot of an RSV vaccine protects adults ages 60 or older from RSV-associated hospitalization and critical illness during two consecutive RSV seasons, according to a new study.
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CARB-X backs neonatal sepsis diagnostic platform by Quantamatrix
CARB-X has awarded QuantaMatrix Inc. US$2.85M to execute a workplan to develop its rapid diagnostic platform to detect sepsis, especially in vulnerable neonates. The test aims to deliver results within just 6 hours from very small blood samples of 1 to 2 milliliters.
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New sepsis diagnostic could reduce critical time to save patients
A new diagnostic method would confirm sepsis infections earlier, cutting critical hours in the “race against time” to save patients’ lives. The process uses a centrifuge to separate bacteria from blood cells, and automatic microscopy for detection.
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New ‘cough simulator’ mimics TB transmission with unprecedented accuracy
Researchers have developed a new experimental system called Transmission Simulation System (TSS) that replicates the airborne transmission of TB – by simulating the human cough – with unparalleled realism and never-before-seen precision.
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Guideline on respiratory infections in leukemia revised
People with leukemia have a weakened immune system due to the disease itself and treatment, which leads to an increased susceptibility to infections. In a revised guideline, experts summarize the findings of the past ten years on all viruses that cause respiratory infections.
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MERIT grant awarded to study cure for HIV
A scientific team has received an NIH MERIT Award to provide long-term grant support to study a handful of people who have managed to clear HIV after a stem cell transplant and those who did not.
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Pertussis resurgence in Tuscany outlines importance of timely vaccination in Italy
Research analysing 2016-2024 data from all pertussis-related hospitalisations in Tuscany, Italy, finds a ninefold increase in pertussis cases in 2024 among children and adolescents.
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Deadly infectious bone disease wiped out long-necked dinosaurs in Brazil
Researchers found sauropod bones with signs of osteomyelitis, an infectious disease that can be caused by viruses, bacteria, fungi, or protozoa and that killed the animals quickly. The discovery suggests that favorable conditions for the disease existed.
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New bacterium discovered in the Amazon is closely related to Andean species that causes human bartonellosis
A new species of bacteria of the genus Bartonella has been found in the Amazon National Park in the state of Pará, Brazil, in phlebotomine insects, also known as sand flies. Its DNA is similar to that of two other Andean species of bacteria.
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New research rewrites origins of world’s first recorded pandemic - the Plague of Justinian
For the first time, researchers have uncovered direct genomic evidence of the bacterium behind the Plague of Justinian — the world’s first recorded pandemic — in the Eastern Mediterranean, where the outbreak was first described nearly 1,500 years ago.
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Next-generation ‘molecular scissors’ may offer hope for chronic hepatitis B sufferers
Researchers have developed engineered precision ’molecular scissors’ that can permanently disable the genetic blueprint of the hepatitis B virus (HBV). The approach directly targets covalently closed circular DNA (cccDNA), the stubborn viral reservoir.
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Myocardial infarction may be an infectious disease
A pioneering study has demonstrated for the first time that myocardial infarction may be an infectious disease. This discovery challenges the conventional understanding of the pathogenesis of myocardial infarction and opens new avenues for treatment.
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New research makes first broad-spectrum antiviral
A new study offers a promising path toward the development of the world’s first broad-spectrum antiviral (BSA), which could be deployed against a wide range of deadly viruses, including future pandemic threats.
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Global Virus Network announces 2025 Rising Star Mentorship Program Awardees
The Global Virus Network (GVN) has announced the five distinguished recipients of its 2025 Rising Star Mentorship Program. The program is designed to support early-career virologists poised to become the next generation of global leaders in pandemic preparedness and infectious disease research.
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Kiss goodbye to deadly disease – new research finds ‘Pac-Man’ antibodies for killer parasite
Researchers have successfully produced antibodies that kill the parasite carried by the ‘kissing bug’ that causes the potentially deadly Chagas disease. The research is a vital step towards the development of the first effective vaccine.
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Researchers create faster way to trace how diseases spread indoors
Researchers have developed a new method of monitoring and tracking how disease-causing particles, or pathogens, spread from one place to another. The tool could help contain future outbreaks of diseases like COVID-19.
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Global analysis reveals overlooked hotspots at risk for long COVID due to early disability burdens
An international team of researchers has conducted the most comprehensive global-to-local analysis to date on long COVID risk, using disability data from the height of the pandemic to identify vulnerable populations.