All Infectious Disease articles – Page 3
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Hep E virus can live out entire life cycle in kidney cells
Scientists have succeeded in proving in cell culture that hepatitis E viruses can infect kidney cells and can multiply with their help. The entire replication cycle of the virus takes place in kidney cells in the same way as in liver cells, their study shows.
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Vaccination support program reduces pneumonia-related mortality by 25 per cent among the elderly
Findings based on efforts in Sera Town, Japan showed the pneumococcal vaccination support program reversed the previously increasing trend in pneumonia mortality rate in the community.
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Research opens up new avenue for tuberculosis drug discovery
Researchers studied an enzyme from the TB bacterium called alpha-methylacyl-CoA racemase (MCR) which helps the bacterium use cholesterol as an energy source. Blocking this enzyme would therefore starve the bacterium of a major food source, helping to treat TB infections.
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Study yields new insights into infection strategy of Pseudomonas aeruginosa
Scientists have uncovered a previously unknown trick used by Pseudomonas aeruginosa - the bacterium can functionally organize itself in diverse ways within a population of identical clones, as if it were not just one germ, but many at once. A mechanism of epigenetic memory preserves the activity of certain genes across generations.
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New collaboration harnesses COVID methods to combat multi-billion threat to UK forests
Harnessing methods used to successfully predict and understand the spread of COVID-19 during the pandemic, a new project aims to combat the impact of forest diseases that can cost the UK economy billions.
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Novel flu vaccine adjuvant improves protection against influenza viruses, study finds
Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus challenges when combined with a mucosal adjuvant that enhances the body’s immune response, according to a study.
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New ECDC weekly reports and guidance to tackle mosquito-borne diseases across Europe
As Europe enters this year’s mosquito season, ECDC has launched a new series of weekly epidemiological surveillance updates and public health guidance on mosquito-borne diseases.
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Antibiotics are failing in many countries in Africa, new study reveals
The largest retrospective study on resistance to antibiotics in Africa highlights the need for major investments to enhance laboratory capabilities and healthcare access.
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Airborne fungal spores may help predict COVID-19 & flu surges
Monitoring fungal spores in the outdoor air can predict surges in flu and COVID-19 infections, especially during the fall, according to a new study
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With AI, researchers find increasing immune evasion in H5N1
A new analysis suggests that the H5N1 avian influenza virus is evolving clever strategies. Using artificial intelligence tools, researchers analyzed thousands of viral proteins and found that their bonds to protective antibodies have weakened over time.
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Study links influenza A viral infection to microbiome, brain gene expression changes
Infection with influenza A is found to be associated with disruptions in newborn piglets’ nasal and gut microbiomes and with potentially detrimental changes in gene activity in the hippocampus, a brain structure that plays a central role in learning and memory.
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New test could save lives from deadly fungal infection that spiked during pandemic
A new lateral-flow test could one day save lives across the world through early detection of a deadly fungal disease which dramatically spiked during the COVID-19 pandemic.
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Supercharged HIV vaccine could offer strong protection with just one dose
Researchers have shown that they can generate a strong immune response to HIV with just one vaccine dose, by adding two powerful adjuvants — materials that help stimulate the immune system.
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How a common brain parasite disrupts neural communication
Scientists reveal how the Toxoplasma parasite can significantly disrupt brain function, even when it infects only a small number of neurons. The team found the parasite interferes with essential communication between brain cells.
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Vaccine disguised as a virus tricks the body into stronger immunity
A simple addition to mRNA vaccines can significantly enhance their effectiveness. Scientists have shown that mice develop a stronger and longer-lasting immune response when the mRNA vaccine is disguised as virus-like particles.
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New RNA test for African trypanosomiasis in livestock aids control efforts
A new state-of-the-art diagnostic test for animal African trypanosomiasis could detect sentinels of infection in domestic animals and aid control efforts.
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Herpes virus plays interior designer with human DNA
Researchers have discovered the cold sore virus reshapes the human genome’s architecture, rearranging its shape in three-dimensional space so that HSV-1 can access host genes most useful for its ability to reproduce.
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New vaccine works against multiple fungal infections
A vaccine developed by University of Georgia researchers successfully protects against and treats vaginal yeast infections in mice, according to a study.
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Scientists discover key protein that enables ‘shock & kill’ strategy for HIV latent virus clearance
Researchers have identified a specific gene transcription factor, BRD9, as a potential key to unlocking the mechanisms behind HIV-1 latency.
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Paper-based devices diagnose malaria in asymptomatic people
Devices made with cheap strips of paper have outperformed two other testing methods in detecting malaria infection in asymptomatic people in Ghana – a diagnostic advance that could accelerate efforts to eliminate the disease, researchers say.