All Infectious Disease articles – Page 5
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Current antivirals likely less effective against severe infection caused by bird flu virus in cows’ milk
Scientists found that in a preclinical model, two FDA–approved flu antivirals generally did not successfully treat severe H5N1 infections. Meanwhile, the route of infection, whether through the eye, the nose or the mouth, significantly impacts effectiveness.
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Metagenomic analysis of tick-borne viruses in Inner Mongolia
A new study maps the landscape of TBVs in Inner Mongolia, but also highlights the potential spillover risk of TBVs. These findings underscore the urgent need for One Health strategies for monitoring emerging TBVs at the tick-human-livestock interface in northern China.
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Ultra-low dose CT aids pneumonia diagnosis in immunocompromised patients
Denoised ultra-low dose CT can effectively diagnose pneumonia in immunocompromised patients using only 2% of the radiation dose of standard CT, according to a study.
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‘Overlooked’ scrub typhus may affect 1 in 10 in rural India
A study of over 32,000 people living in Tamil Nadu, India, suggests scrub typhus infection may affect up to 10% of rural populations annually and is a leading yet under-recognised cause of hospitalisations for fever across India.
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Measles on the rise again in Europe: Time to check your vaccination status
Eight out of ten people who were diagnosed with measles in the EU/EEA in the last year were not vaccinated, according to a new measles and rubella update.
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Researchers announce breakthrough in next-generation polio vaccines
Researchers have taken a major step towards producing a more affordable and lower-risk polio vaccine using virus-like particles (VLPs). These particles mimic the outer protein shell of poliovirus, but are empty inside.
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Meningococcal vaccine found to be safe and effective for infants in sub-Saharan Africa
A new global health study found a vaccine that protects against five strains of meningitis prevalent in sub-Saharan Africa is safe and effective for use in young children beginning at 9 months of age.
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Multi-dose vaccines administered in the same site boost immune response
New research suggests that receiving multiple doses of a vaccine in the same limb leads to faster antibody development, an important strategy for providing immunity as quickly as possible during a pandemic or disease outbreak.
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Intranasal herpes infection may produce neurobehavioral symptoms, study finds
A new study finds that herpes infection through the nose can lead to anxiety, motor impairment and cognitive issues. The research is the first to show that, by exploiting a cellular enzyme, the virus can produce behavioral symptoms.
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Study discovers tuberculosis genes necessary for airborne transmission
Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person’s lungs to another person’s during coughing, sneezing or talking, according to a study that offers new targets for tuberculosis therapies.
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Inhaled COVID vaccine study begins recruitment for phase-2 human trials
Researchers have started a phase-2 clinical trial on a next-generation, inhaled COVID-19 vaccine. Findings from the phase-1 trial indicate that the vaccine is more effective at inducing immune responses than traditional injected vaccines are.
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Purified immunoglobulin F(ab′) 2 prevents lethal staphylococcal enterotoxin B intoxication in mice and rhesus monkeys
Purified F(ab′)2 fragments are an effective antidote to lethal SEB doses in mice and rhesus monkeys, and therefore might be a favorable candidate for treating patients with severe SEB intoxication, a new study suggests.
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Scientists develop low-cost handheld sensor test for airborne bird flu
Researchers have developed a prototype sensor that detects a virus that causes bird flu (H5N1) in air samples. The low-cost handheld sensor detects the virus at levels below an infectious dose and could lead to rapid aerosol testing for airborne avian influenza.
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Novel insights into Candida glabrata in pregnant women’s reproductive tracts in Hainan
A study of Candida glabrata in pregnant women with vaginal discomfort at Haikou Maternal and Child Health Hospital found that 64.5% of the 594 yeast isolates (383 isolates) showed resistance (R) or intermediate (I) phenotypes to at least one of four commonly used antifungals.
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Eradivir announces Phase 2 human challenge study of EV25 in healthy adults infected with influenza
Eradivir, a clinical-stage small molecule immunotherapy biotech company, announced it has begun a Phase 2 challenge study with its antiviral therapeutic, EV25.
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Fewer than half of parents think they have accurate information about bird flu
Most parents say they don’t know if there have been cases of bird flu in their state, and less than half feel that they are able to find accurate and current information about it, according to a new national US poll.
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BAADesign enables the immune escaped etesevimab fully-armed against SARS-CoV-2 Omicron subvariants
BAADesign offers a powerful tool for reengineering monoclonal antibodies to combat emerging SARS-CoV-2 variants, providing a scalable solution for future pandemic preparedness, according to a new study.
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New biosensor can detect airborne bird flu in under 5 minutes
A new biosensor for monitoring aerosol particles of H5N1 works within five minutes, preserving the sample of the microbes for further analysis and providing a range of the pathogen concentration levels detected on a farm.
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Study: Smartwatches could end the next pandemic
Everyday smartwatches are extremely accurate in detecting viral infection long before symptoms appear — new research shows how they could help stop a pandemic before it even begins.
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The math behind social distancing: the rules that influence epidemic behavior
Researchers have worked out how to understand social distancing behavior. The team identified simple rules that govern how individuals adapt their behavior during an epidemic in order to balance the costs of infection and social distancing.