All Infectious Disease articles – Page 5
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NewsEngineered gut bacteria therapy emerges as scalable potential alternative to fecal microbiota transplants following clinical trial
Researchers have developed a new manufacturing platform for producing targeted mixtures of beneficial gut bacteria, an approach that could help expand access to microbiome-based therapies for patients with recurrent Clostridioides difficile (C. difficile) infection.
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NewsReal-time brain monitor detects infections earlier
A research team has created a new monitoring system to save lives and significantly reduce health-care costs in brain-injury cases through the early detection of infections in intensive care units. NeuroSense connects to drainage lines to detect biomarkers of infection.
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NewsPan-European One Health Network established to bolster infectious disease response
iiCON: the Infection Innovation Consortium has successfully secured funding from COST to establish a unique pan-European COST Action network with over 70 collaborators from 21 countries and international organisations to harmonise the European response to infectious disease threats.
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NewsWhat is the link between HIV and chronic pain?
A mouse study reveals a mechanism linking HIV to chronic pain. Targeting each of the molecular players in this mechanism alleviates pain and may hold treatment promise for HIV-associated pain, though more work is needed.
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NewsBehind the diagnosis: How laboratory testing guided a complex histoplasmosis case
A diagnosis of histoplasmosis forced a teenager with juvenile arthritis onto an uncertain path, one defined by months of treatment, recovery, and a long-term course of antifungal therapy expected to last up to three years. Histoplasma capsulatum, a dimorphic fungus that causes histoplasmosis, found its way into her lungs.
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NewsPost-discharge antibiotics may offer limited benefit after pediatric appendicitis
Acute appendicitis is one of the most common surgical emergencies among children, and complicated acute appendicitis (CAA), including perforated or gangrenous disease, carries a higher risk of infection and longer hospitalization. While intravenous antibiotics during hospitalization are standard practice, the role of oral home antibiotics (OHA) after discharge remains controversial. ...
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NewsPrecigen presents new long-term durability data for PAPZIMEOS, recently granted seven-year market exclusivity
Precigen, Inc. has announced updated long-term follow-up data from the pivotal study of PAPZIMEOS™ (zopapogene imadenovec-drba) for the treatment of adults with recurrent respiratory papillomatosis (RRP).
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NewsNew analysis confirms benefits of childhood flu vaccines
Pediatric flu vaccines significantly reduce the number of childhood cases of influenza, new research confirms. The findings show that for every 100 children vaccinated, between nine and 14 fewer children catch the flu.
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NewsProtection for newborns: New treatment aims to prevent meningitis without antibiotics
One of the leading pathogens responsible for meningitis cases in newborn babies is the K1 form of the E. coli bacterium. Now, researchers have developed a triple-pronged approach that seeks to prevent transmission to newborns.
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NewsResearchers discover tick protein that may block disease transmission
Researchers have found that ticks produce an exosomal glycine-rich protein that plays a vital role in helping ticks feed and transmit viruses. When they used genetic tools to silence the gene responsible for this protein, ticks lacking the protein struggled to feed effectively and showed reduced body weight after feeding.
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NewsHealth researchers call for support to develop pandemic prevention
The Vanderbilt Center for Antibody Therapeutics has received large-scale government grants and contracts to fund the discovery of human antiviral antibodies. The problem is the next step — finding corporate partners to develop the antibodies through human testing.
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NewsRecent study reveals how bacteria capture a rare type of sugar molecule
Researchers have identified a novel transport protein that binds cyclic β-1,2-glucans, revealing unexpected diversity in bacterial sugar uptake mechanisms.
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NewsNovel therapeutic drug for tuberculosis is proposed using high-precision molecular simulation
Researchers have proposed a novel therapeutic agent for tuberculosis, using high-precision molecular simulation techniques. The proposed drug is anticipated to bind strongly to the drug-metabolizing enzyme cytochrome P450 (CYP).
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NewsNew antibiotic design could help treat drug-resistant infections
A new study has shown that antibiotics can be chemically redesigned so they are less easily removed by efflux pumps. This allows the antibiotic to remain inside the bacterial cell at higher concentrations, restoring its ability to kill bacteria even when resistance mechanisms are present.
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NewsExperts convened by WHO advise on candidate treatments and vaccines for Ebola disease caused by Bundibugyo virus
In response to the current outbreak of Ebola disease caused by Bundibugyo virus, WHO convened several of its expert and advisory groups to assess potential vaccines and therapeutics for both prevention and treatment of Bundibugyo virus disease (BVD).
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NewsResearchers identify immune ‘energy signature’ linked to tuberculosis protection
Researchers found that circulating monocytes from people with latent TB remain metabolically flexible, allowing them to mount strong antibacterial responses, whereas cells from people with active TB disease show impaired metabolism and weaker responses to infection.
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NewsExperimental HIV vaccine achieves a long-sought goal
In a first for the field, all non-human primates given a new series of vaccines generated antibodies capable of fighting multiple strains of HIV. It brings researchers closer to a vaccine effective against the vast diversity of HIV strains circulating worldwide.
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NewsSeven European countries observe drop in chlamydia notifications especially among young people in 2024
After a decade of general increases in chlamydia cases across Europe, the first signs of a decline suggest a possible common driver. Is it a true reduction and will it be a sustainable one?
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NewsScientists validate a link between autoimmunity in a subset of people with long COVID
A research team has demonstrated that autoimmunity, where the body’s immune system attacks its own tissues, is responsible for the often-debilitating and confounding symptoms of long COVID in a subset of people.
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NewsResearchers may now understand why chikungunya virus infections turn chronic
About half of people infected with chikungunya virus will progress to a chronic form of the disease. A new study finds that chikungunya virus persists in joint-associated macrophages, a specialized type of white blood cell that helps the body defend against pathogens.