All Infectious Disease articles – Page 31
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NewsNew tool reveals the secrets of HIV-infected cells
Scientists have developed a novel tool—named HIV-seq—for profiling the features of rare HIV-infected cells from people with HIV. Using the new tool, they’ve found key differences in people’s HIV-infected cells before versus after starting antiretroviral therapy.
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NewsEditing for timing, not overdrive: A new genetic route to fire blight resistance in apple
Fire blight remains one of the most destructive bacterial diseases threatening global apple production. A new study identifies a family of inducible lectin genes, MdAGGs, as critical components of apple immune defense and demonstrates that their precise activation timing is key to effective resistance.
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NewsNanoparticle vaccine approach takes on a new target: Hepatitis C virus
Scientists have engineered a native-like, stabilized version of Hepatitis C virus’s E1E2 complex and used it to build a nanoparticle-based vaccine candidate. It uses a technology called self-assembling protein nanoparticles, which organizes copies of the proteins into virus-like clusters that the immune system can recognize.
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NewsHuge toll: Bird flu rampant among black vultures
More than four out of every five dead black vultures examined by University of Georgia researchers tested positive for highly pathogenic avian influenza, according to a new study. Their indiscriminate scavenging appears to sustain transmission of the virus beyond the typical bird flu season.
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NewsUltrasound-activated ‘nanoagents’ kill superbugs hiding in biofilms
Scientists have designed nanoagents that act like smart drug‑delivery capsules – carrying an antibiotic deep into bacterial infection sites and releasing it only when activated by gentle ultrasound.
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NewsScientists identify therapeutic target that would curb the spread of coronaviruses
Coronaviruses not only use the machinery of the human cells they infect: they modify it to achieve optimal conditions to produce viral proteins and thus spread more quickly, according to a study identifying enzymes that modify transfer RNAs as key elements for coronavirus infection.
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NewsCell-free DNA offers early warning for bloodstream infections in kids with leukemia
Researchers show that microbial cell-free DNA sequencing can predict bloodstream infections in children with leukemia days before the symptoms appear. Plasma microbial cell-free DNA sequencing (mcfDNA-Seq) offer a potential approach to protecting vulnerable patients by allowing treatment to start before the patient gets sick.
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NewsNew study demonstrates universal newborn cCMV screening leads to earlier detection and increased identification of mild hearing loss
A new retrospective cohort study examining the impact of Minnesota’s first-in-the-nation mandated universal newborn screening for congenital cytomegalovirus (cCMV) shows that universal screening significantly decreased the age at first audiology visit and increased identification of mild hearing loss in infants.
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NewsBiomarkers indicating higher liver cancer risk in chronic hepatitis B patients identified
Researchers have identified Hepatitis B RNA serum levels as a biomarker that more accurately stratifies risk of liver cancer in individuals who have been functionally cured of chronic hepatitis B.
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NewsStudy reveals immune blueprint for next-generation malaria vaccine
New research has uncovered how the human immune system fights Plasmodium vivax, paving the way for the first effective vaccine against the most widespread form of malaria. It provides critical evidence of how protective immunity to P. vivax works, identifying specific targets on the parasite.
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NewsTackling tuberculosis systematically: How the environment shapes TB risk
Researchers introduce the concept of the “tuberculogenic environment”: the complex interplay of structures, rules, and living conditions that keep certain communities at high TB risk, even when care is available.
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NewsA highly precise target for medications against tropical diseases
Researchers have discovered a critical vulnerability shared by the pathogens that cause African sleeping sickness, Chagas disease and leishmaniasis. The PEX38 protein plays a crucial role in the formation of certain organelles of the trypanosomes that are essential for their energy supply.
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NewsFe₃O₄@mPEG-Ag nanoparticles: a new frontier in combating antibiotic resistance
A collaborative study introduces Fe₃O₄@mPEG-Ag nanoparticles (NPs) as a groundbreaking non-antibiotic strategy to combat drug-resistant bacteria, offering the antibacterial properties of silver (Ag) with the stability and biocompatibility of magnetite (Fe₃O₄) modified by methoxy poly(ethylene glycol) (mPEG).
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NewsImaging technique is step towards needed treatments for hantaviruses in new molecular ma
Researchers have produced a detailed blueprint, the highest resolution yet, for a protein complex the Andes virus uses to infect host cells. The new detailed structural information enabled the researchers to produce a vaccine candidate that caused mice to produce neutralizing antibodies against the Andes virus.
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NewsAcoziborole Winthrop receives European Medicines Agency positive opinion as three-tablet, single-dose treatment for most common form of sleeping sickness
The European Medicines Agency has granted a positive opinion to Acoziborole Winthrop (acoziborole) as a single-dose oral treatment for both early- and advanced-stage gambiense sleeping sickness in adults as well as in adolescents 12 years and older weighing at least 40 kilograms.
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NewsSource or sink? Trees with heart rot disease emit more methane, upending forest carbon models
New research suggests that upland forests harboring trees with a common and incurable fungal disease known as heart rot could actually be emitting more methane than they take in, therefore releasing more greenhouse gases than previously thought.
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NewsScientists identify key protein that stops malaria parasite growth
An international team of scientists have identified a unique protein essential for the malaria parasite’s survival and transmission. Aurora-related kinase 1 (ARK1) acts as a ‘traffic controller’ during the parasite’s unusual cell division and growth process.
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NewsDiffering immune responses in infants may explain increased severity of RSV over SARS-CoV-2
Reseachers report that the two respiratory viruses trigger different immune responses. Those differences might explain why these two diseases have different clinical outcomes and require different treatment strategies.
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NewsCOVID-19 infection predicts higher risk of kidney disease, study finds
Researchers have found that previous COVID-19 infection is a significant risk factor for kidney disease. Compared to influenza, those with a history of COVID-19 infection have a 2.3-times higher risk of acute kidney injury and a 1.4-times higher risk of chronic kidney disease, according to an analysis of over three million patients.
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NewsEmerging class of antibiotics to tackle global tuberculosis crisis
Researchers investigated how three naturally occurring antibiotic compounds – ecumicin, ilamycin and cyclomarin – act on a vital protein degradation machine inside Mycobacterium tuberculosis, the bacterium that causes TB.