All inflammatory bowel disease articles
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NewsUnderstanding inflammatory bowel disease: An integrative framework of microbiome, metabolome, and immunological biomarkers
A new review underscores the interconnected roles of microbial, metabolic, and immune biomarkers in IBD. While current biomarkers lack universal specificity, integrative approaches and AI-driven analyses offer transformative potential for precision medicine in IBD care.
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NewsImmune tolerance to gut microbes is initiated by a key bacterial sensor
A study has found that the body’s immune “tolerance” to gut microbes depends on an ancient bacterial-sensing protein called STING—normally considered a trigger for inflammation.
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NewsGut bacteria may hold key to unlocking better cancer treatment
Scientists have discovered a range of microbial ‘biomarkers’ that could help to improve detection and treatment of gastrointestinal diseases (GIDs) such as gastric cancer (GC), colorectal cancer (CRC), and inflammatory bowel disease (IBD).
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NewsMicrobial proteins reveal chemical signatures of body sites and inflammation
A new study shows that protein sequences associated with microbial communities in the human gut have uniquely low stoichiometric water content and undergo counterintuitive chemical shifts toward chemically reduced states during inflammation.
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NewsA digestive ‘treasure chest’ shows promise for targeted drug treatment in the gut
A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments.
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NewsPartnering diet and intestinal microbes to protect against GI disease
New research suggests that we could get more out of our diets by harnessing intestinal microbes to break down plant compounds collectively known as phenolic glycosides. These compounds pair sugar molecules with a host of small molecules beneficial to human health.
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NewsAMI member Christopher Stewart named as finalist in 2025 UK Blavatnik Awards for Young Scientists
Applied Microbiology International member Dr Christopher Stewart of Newcastle University has been named as a finalist for the eighth Blavatnik Awards for Young Scientists in the UK. He is the 2023 winner of AMI’s WH Pierce Prize for microbiology.
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NewsWe know what you ate: Detailed protein maps assess intestinal health
A new method has been designed to map the near-exact molecular details of the human and bacterial protein regulations within the host-gut microbiome interactions. These proteins could be used for medical and dietary intervention to maintain intestinal health.
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NewsWinners of Applied Microbiology International Horizon Awards 2024 announced
The winners of the Applied Microbiology International Horizon Awards 2024 have been announced.
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NewsLandmark study reveals how antibiotics contribute to inflammatory bowel disease risk
Researchers have uncovered crucial insights into how antibiotic use increases the risk of inflammatory bowel disease (IBD), demonstrating that antibiotics interfere with the protective mucus layer in the intestine.
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CareersA conversation at the forefront of human microbiome research
Yang Yue and Professor Alan Walker discuss everything from precision medicine and the omics approach, to challenges in the road ahead and the future of microbiome research.
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NewsMicrorobot-packed pill shows promise for treating inflammatory bowel disease in mice
Engineers at the University of California San Diego have developed a pill that releases microscopic robots, or microrobots, into the colon to treat inflammatory bowel disease (IBD). The experimental treatment, given orally, has shown success in mice.
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News5S-Heudelotinone alleviates experimental colitis by shaping the immune system and enhancing the intestinal barrier
A new study discusses how 5S-Heudelotinone alleviates experimental colitis by shaping the immune system and enhancing the intestinal barrier in a gut microbiota-dependent manner.
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NewsGut bacteria and inflammatory bowel disease: a new frontier in treatment
A new review highlights the therapeutic potential of various prebiotics derived from different food sources for manipulating gut bacteria.
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NewsCryptic genetic element in the human gut could double as sensitive biomarker
A study shows that a mysterious plasmid that is highly prevalent in the human gastrointestinal tract could be used to identify faecal contamination and offer insights into the severity of intestinal diseases.
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NewsStudy reveals possible triggers for inflammatory bowel disease
A new study finds a complex interplay between diet, genes, and the gut microbiota that could explain why IBD develops.
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NewsResearchers call for regulation of direct-to-consumer microbiome tests
Scientists argue that direct-to-consumer (DTC) microbiome tests lack analytical and clinical validity and require more federal regulation to prevent consumer harm.
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NewsReverse metabolomics method finds biomarker for inflammatory bowel disease
Scientists develop a groundbreaking approach to microbiome research, improving its ability to explain and treat disease.
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NewsEarly life exposure to broccoli sprouts protects against colitis in IBD
High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD), according to a study conducted in mice.
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NewsGut microbiota-derived 7-DHC tackles circadian rhythm disorders and IBD
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract categorized into ulcerative colitis and Crohn’s disease. Currently, aminosalicylates, glucocorticoids, immunomodulating drugs, and biological agents are common strategies for the treatment of IBD. The efficacy of these therapies is limited, however, and they are ...