All inflammatory bowel disease articles
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NewsHarmless Klebsiella strain shows powerful protection against gut infections in Inflammatory Bowel Disease (IBD) model
A new study demonstrates that a harmless strain of Klebsiella can eliminate infections and reduce gut inflammation in mouse models of inflammatory bowel disease (IBD).
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NewsEverolimus alleviates ulcerative colitis via inflammation suppression and microbiota remodeling
A new study reveals how targeting the CLEC4E receptor and reshaping the gut metabolite axis offers a promising therapeutic avenue for inflammatory bowel disease.
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NewsThe power of gut enzymes: why healthy eating affects everyone differently
Researchers have uncovered a mechanism that determines how our gut microbiome processes healthful plant compounds. The chemical cookbook of gut bacteria varies from person to person—and is often disrupted in chronic diseases.
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NewsBacteria ‘pills’ could detect gut diseases — without the endoscope
Researchers report that they’ve developed a sensor made of tiny microspheres packed with blood-sensing bacteria that detect markers of gastrointestinal disease. Taken orally, the miniature “pills” also contain magnetic particles that make them easy to collect from stool. Excreted from mouse models with colitis, the bacterial sensor detected gastrointestinal bleeding within minutes.
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NewsDangerous E. coli strain blocks gut’s defense mechanism to spread infection
When harmful bacteria invade through the digestive tract, gut cells usually fight back by pushing infected cells out of the body to stop the infection from spreading. Scientists have discovered that a dangerous strain of E. coli can block gut this defense, allowing the bacteria to spread more easily.
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NewsScientists develop a way to track donor bacteria after fecal microbiota transplants
Researchers have developed a new technology to track beneficial bacteria for up to 5 years after fecal microbiota transplants (FMT). The method allows scientists to distinguish even closely related bacterial strains and identify each one’s unique genetic “fingerprint.”
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NewsMicrobiome and nanoparticle discoveries hold promise for treating gut pain
In an effort to develop targeted treatments for gut pain, scientists have discovered a new enzyme in gut bacteria and are using nanoparticles to deliver drugs inside cells. PAR2, a receptor involved in pain signaling, is activated by certain enzymes called proteases.
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NewsNew antibiotic targets IBD — and AI predicted how it would work before scientists could prove it
The new antibiotic, enterololin, attacks and kills only a specific group of disease-causing bugs, which includes the type of E. coli that drives Crohn’s disease. It is a promising new treatment option for people affected by Crohn’s and other IBD-related conditions.
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NewsUnderstanding inflammatory bowel disease: An integrative framework of microbiome, metabolome, and immunological biomarkers
A new review underscores the interconnected roles of microbial, metabolic, and immune biomarkers in IBD. While current biomarkers lack universal specificity, integrative approaches and AI-driven analyses offer transformative potential for precision medicine in IBD care.
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NewsImmune tolerance to gut microbes is initiated by a key bacterial sensor
A study has found that the body’s immune “tolerance” to gut microbes depends on an ancient bacterial-sensing protein called STING—normally considered a trigger for inflammation.
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NewsGut bacteria may hold key to unlocking better cancer treatment
Scientists have discovered a range of microbial ‘biomarkers’ that could help to improve detection and treatment of gastrointestinal diseases (GIDs) such as gastric cancer (GC), colorectal cancer (CRC), and inflammatory bowel disease (IBD).
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NewsMicrobial proteins reveal chemical signatures of body sites and inflammation
A new study shows that protein sequences associated with microbial communities in the human gut have uniquely low stoichiometric water content and undergo counterintuitive chemical shifts toward chemically reduced states during inflammation.
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NewsA digestive ‘treasure chest’ shows promise for targeted drug treatment in the gut
A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments.
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NewsPartnering diet and intestinal microbes to protect against GI disease
New research suggests that we could get more out of our diets by harnessing intestinal microbes to break down plant compounds collectively known as phenolic glycosides. These compounds pair sugar molecules with a host of small molecules beneficial to human health.
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NewsAMI member Christopher Stewart named as finalist in 2025 UK Blavatnik Awards for Young Scientists
Applied Microbiology International member Dr Christopher Stewart of Newcastle University has been named as a finalist for the eighth Blavatnik Awards for Young Scientists in the UK. He is the 2023 winner of AMI’s WH Pierce Prize for microbiology.
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NewsWe know what you ate: Detailed protein maps assess intestinal health
A new method has been designed to map the near-exact molecular details of the human and bacterial protein regulations within the host-gut microbiome interactions. These proteins could be used for medical and dietary intervention to maintain intestinal health.
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NewsWinners of Applied Microbiology International Horizon Awards 2024 announced
The winners of the Applied Microbiology International Horizon Awards 2024 have been announced.
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NewsLandmark study reveals how antibiotics contribute to inflammatory bowel disease risk
Researchers have uncovered crucial insights into how antibiotic use increases the risk of inflammatory bowel disease (IBD), demonstrating that antibiotics interfere with the protective mucus layer in the intestine.
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CareersA conversation at the forefront of human microbiome research
Yang Yue and Professor Alan Walker discuss everything from precision medicine and the omics approach, to challenges in the road ahead and the future of microbiome research.
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NewsMicrorobot-packed pill shows promise for treating inflammatory bowel disease in mice
Engineers at the University of California San Diego have developed a pill that releases microscopic robots, or microrobots, into the colon to treat inflammatory bowel disease (IBD). The experimental treatment, given orally, has shown success in mice.