All inflammatory bowel disease articles
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NewsVitamin D linked to immune response to gut microbiome in inflammatory bowel disease
Vitamin D supplementation may help shape how the immune system responds to gut bacteria in people with inflammatory bowel disease (IBD), according to a new study.
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NewsFiber in whole wheat foods protects against gut inflammation in mice, study finds
Enriching the diet with wheat fiber protects mice against intestinal inflammation, according to a study. The finding helps explain why incidence of inflammatory bowel disease (IBD) has increased, and suggests eating whole wheat foods may reduce one’s risk of developing it.
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News‘Hidden’ bugs in our gut appear key to good health, finds global study
A single group of bacteria has repeatedly shown up in high numbers in the gut microbiomes of healthy people. Scientists found the level of CAG-170 bacteria present was consistently higher in healthy people than those with diseases including inflammatory bowel disease, obesity and chronic fatigue syndrome.
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NewsHow a single gene shapes gut health and IBD risk
Two recent studies highlight the role of a gene called PTPN2 in protecting the gut from harmful bacteria linked to inflammatory bowel disease (IBD). When PTPN2 does not function properly, the gut becomes more vulnerable to infection and inflammation.
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NewsNew test could help pinpoint IBD diagnosis, study finds
A test that rapidly detects signs of inflammatory bowel disease (IBD) in stool samples could improve future diagnosis and monitoring of the condition, a study suggests. The luminescent reporter lights up when it detects a molecule linked to gut inflammation.
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NewsGut bacteria changes at the earliest stages of inflammatory bowel disease
People newly diagnosed with the most common IBD subtypes, Crohn’s disease and ulcerative colitis, lose beneficial anaerobic bacteria that help with digestion of complex carbohydrates. Patients instead experience a rise in oxygen-tolerant bacteria from the mouth that travel in the gut.
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NewsHarmless Klebsiella strain shows powerful protection against gut infections in Inflammatory Bowel Disease (IBD) model
A new study demonstrates that a harmless strain of Klebsiella can eliminate infections and reduce gut inflammation in mouse models of inflammatory bowel disease (IBD).
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NewsEverolimus alleviates ulcerative colitis via inflammation suppression and microbiota remodeling
A new study reveals how targeting the CLEC4E receptor and reshaping the gut metabolite axis offers a promising therapeutic avenue for inflammatory bowel disease.
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NewsThe power of gut enzymes: why healthy eating affects everyone differently
Researchers have uncovered a mechanism that determines how our gut microbiome processes healthful plant compounds. The chemical cookbook of gut bacteria varies from person to person—and is often disrupted in chronic diseases.
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NewsBacteria ‘pills’ could detect gut diseases — without the endoscope
Researchers report that they’ve developed a sensor made of tiny microspheres packed with blood-sensing bacteria that detect markers of gastrointestinal disease. Taken orally, the miniature “pills” also contain magnetic particles that make them easy to collect from stool. Excreted from mouse models with colitis, the bacterial sensor detected gastrointestinal bleeding within minutes.
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NewsDangerous E. coli strain blocks gut’s defense mechanism to spread infection
When harmful bacteria invade through the digestive tract, gut cells usually fight back by pushing infected cells out of the body to stop the infection from spreading. Scientists have discovered that a dangerous strain of E. coli can block gut this defense, allowing the bacteria to spread more easily.
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NewsScientists develop a way to track donor bacteria after fecal microbiota transplants
Researchers have developed a new technology to track beneficial bacteria for up to 5 years after fecal microbiota transplants (FMT). The method allows scientists to distinguish even closely related bacterial strains and identify each one’s unique genetic “fingerprint.”
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NewsMicrobiome and nanoparticle discoveries hold promise for treating gut pain
In an effort to develop targeted treatments for gut pain, scientists have discovered a new enzyme in gut bacteria and are using nanoparticles to deliver drugs inside cells. PAR2, a receptor involved in pain signaling, is activated by certain enzymes called proteases.
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NewsNew antibiotic targets IBD — and AI predicted how it would work before scientists could prove it
The new antibiotic, enterololin, attacks and kills only a specific group of disease-causing bugs, which includes the type of E. coli that drives Crohn’s disease. It is a promising new treatment option for people affected by Crohn’s and other IBD-related conditions.
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NewsUnderstanding inflammatory bowel disease: An integrative framework of microbiome, metabolome, and immunological biomarkers
A new review underscores the interconnected roles of microbial, metabolic, and immune biomarkers in IBD. While current biomarkers lack universal specificity, integrative approaches and AI-driven analyses offer transformative potential for precision medicine in IBD care.
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NewsImmune tolerance to gut microbes is initiated by a key bacterial sensor
A study has found that the body’s immune “tolerance” to gut microbes depends on an ancient bacterial-sensing protein called STING—normally considered a trigger for inflammation.
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NewsGut bacteria may hold key to unlocking better cancer treatment
Scientists have discovered a range of microbial ‘biomarkers’ that could help to improve detection and treatment of gastrointestinal diseases (GIDs) such as gastric cancer (GC), colorectal cancer (CRC), and inflammatory bowel disease (IBD).
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NewsMicrobial proteins reveal chemical signatures of body sites and inflammation
A new study shows that protein sequences associated with microbial communities in the human gut have uniquely low stoichiometric water content and undergo counterintuitive chemical shifts toward chemically reduced states during inflammation.
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NewsA digestive ‘treasure chest’ shows promise for targeted drug treatment in the gut
A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments.
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NewsPartnering diet and intestinal microbes to protect against GI disease
New research suggests that we could get more out of our diets by harnessing intestinal microbes to break down plant compounds collectively known as phenolic glycosides. These compounds pair sugar molecules with a host of small molecules beneficial to human health.