All latency articles
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NewsScientists discover how leukemia virus stays hidden in the body
A research team has discovered how the human T-cell leukemia virus type 1 (HTLV-1) silently persists in the body. Their findings identify a previously unknown genetic “silencer” element that keeps the virus in a dormant, undetectable state.
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NewsScientists discover key protein that enables ‘shock & kill’ strategy for HIV latent virus clearance
Researchers have identified a specific gene transcription factor, BRD9, as a potential key to unlocking the mechanisms behind HIV-1 latency.
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NewsHIV discovery could open door to long-sought cure
Scientists have uncovered a key reason why HIV remains so difficult to cure: Their research shows that small changes in the virus affect how quickly or slowly it replicates, and how easily or stubbornly it can reawaken from hiding.
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NewsResearchers reveal HIV latency reversing properties in African plant
Scientists have uncovered mechanisms of a medicinal plant with anti-HIV potential. Croton oligandrus Pierre & Hutch is a species of tree used in traditional healing in Cameroon to treat a variety of diseases and conditions including cancers and diabetes.
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NewsNew HIV reporter model: Visualizing HIV viral dynamics in cells with dual fluorescence
Researchers have developed a novel viral reporter system that allows for real-time visualization of HIV dynamics post-viral infection. HIV-Tocky features dual fluorescence to illuminate the process of provirus silencing and reactivation.
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NewsReactivation compound could be latest weapon against HIV
A research team has identified a molecular compound that activates latent HIV-1 in cells, showing promise for HIV treatments.
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NewsNew research shows HIV can lie dormant in the brain
Researchers in the UNC School of Medicine extracted living brain tissue to conclude that specialized immune cells in the brain can harbour latent but replication-competent HIV.
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NewsScientists find two separate reservoirs of latent HIV in patients
Scientists have shown that, addition to HIV’s ability to lay dormant in the blood/lymphoid system, the virus may also lay dormant in the central nervous system, delineating another challenge in creating a cure.