All articles by Linda Stewart – Page 5
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Review explores critical role of microbiome in cancer development and treatment
The human microbiome plays a pivotal role in cancer initiation, progression, and treatment response, according to a major review article published in the open-access journal iMeta. The study, led by an international team of researchers, details how bacteria, viruses, and fungi interact with tumors and the immune system to either promote or inhibit cancer growth.
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One dose of antibiotic treats early syphilis as well as three doses
Researchers have found that a single injection of the antibiotic benzathine penicillin G (BPG) successfully treated early syphilis just as well as the three-injection regimen used by many clinicians. These findings from a late-stage clinical trial suggest the second and third doses of conventional BPG therapy do not provide a health benefit.
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The cling of doom: How staph bacteria latch onto human skin
Scientists have discovered the strongest natural protein bond ever recorded, explaining how Staphylococcus aureus clings so tightly to human skin and pointing to new ways to fight antibiotic resistance.
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CARB-X to support lower respiratory tract infection diagnostic by Zeteo
CARB-X has awarded Zeteo Tech, Inc. US$1M to execute a workplan for its noninvasive diagnostic platform that aims to evaluate whether exhaled breath can diagnose lower respiratory tract infections (LRTIs) in high-risk populations within critical care environments.
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Bacteria that ‘shine a light’ on microplastic pollution
Researchers have developed a living sensor that attaches to plastic and produces green fluorescence. In an initial test on real-world water samples, the biosensor could easily detect environmentally relevant levels of microplastics.
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Research team on quest to engineer computing systems from living cells
A research team has received a $1.99 million grant to lead research on engineered bacterial consortia that could form the basis of biological computing systems. They aim to integrate microbial sensing and communication with electronic networks, paving the way for computing systems constructed from living cells instead of traditional silicon-based hardware.
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Bacteria rewire digestive systems to turn plant waste into power
A new study shows that Pseudomonas putida, a common soil bacterium, completely reorganizes its metabolism to thrive on complex carbons from lignin. By slowing down some metabolic pathways while accelerating others, the bacterium manages to extract energy from lignin without exhausting itself.
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Clinical study shows that nasal spray containing azelastine reduces risk of coronavirus infection by two-thirds
In addition to showing a marked reduction in coronavirus infections, the azelastine group also displayed fewer symptomatic SARS-CoV-2 infections, a lower overall number of confirmed respiratory infections, and, unexpectedly, a reduced incidence of rhinovirus infections, another major cause of respiratory illness.
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Study suggests link between hepatitis B immunity and lower risk of developing diabetes
A research study shows that overall HBV immunity is linked with a 15% lower risk of diabetes, with higher protection in younger people and those with higher immunity shown by higher antibody levels.
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Zoo poo might hold the secrets to new medical treatments
Scientists are hoping the collection of poo from tigers, elephants, giraffes and other exotic animals, could contain the secret to finding new medical treatments. Although a waste product to the animals, hidden amongst it are thousands of phages which are potentially capable of fighting bacterial infections.
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Unlocking how bacteria bounce back after antibiotics
A groundbreaking study has uncovered how Escherichia coli (E. coli) persister bacteria survive antibiotics by protecting their genetic instructions. The work offers new hope for tackling chronic, recurring infections.
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Less is more: Gene loss drives adaptive evolution of a pandemic bacterium
A study reveals a surprising evolutionary insight: sometimes, losing genes rather than gaining them can help bacterial pathogens survive and thrive. The research focused on Vibrio parahaemolyticus, a bacterium behind many of the seafood-related infections worldwide.
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‘Migrion’ – a chimeric structure of virus and migrasome, a novel unit for intercellular viral transmission
Researchers found that in infected cells, nucleic acids and proteins of vesicular stomatitis virus (VSV) are actively transported into migrasomes, newly characterized cellular structures generated specifically during cell migration.
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Therapeutic vaccination against HPV-related tumors: Nanoparticles make the difference
Researchers have developed a therapeutic vaccination concept that can mobilize the immune system to target cancer cells. Virus peptides coupled to silica nanoparticles can elicit effective T-cell responses against HPV-related tumors. In a mouse model, the nanoparticle-based vaccine was able to partially or completely suppress HPV-related tumors.
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Researchers uncover relationship between gut fungi, human genetic variation and disease risk
A study uncovers evidence of the first ternary relationships between human genetic variation, variation in gut mycobiome, and risk of developing chronic disease.
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Ancient mammoth remains yield the world’s oldest host-associated bacterial DNA
An international team has uncovered microbial DNA preserved in woolly and steppe mammoth remains dating back more than one million years. The analyses reveal some of the world’s oldest microbial DNA ever recovered, as well as the identification of bacteria that possibly caused disease in mammoths.
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Study detects multidrug-resistant KPC-producing bacteria in Chilean wastewater for the first time
A team of Chilean researchers has identified, for the first time in the country, the presence of KPC-type carbapenemase-producing bacteria in wastewater samples from the Greater Concepción Metropolitan Area.
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Microalgae are more significant for carbon dioxide absorption in the Southern Ocean than previously thought
14,000 years ago, algal blooms in the Southern Ocean helped to massively reduce the global carbon dioxide content of the atmosphere – as has now been revealed by new analyses of ancient DNA. Declines in sea ice pose a serious threat to these algae.
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New pimple patches deliver a powerful remedy to unwanted zits
Researchers have designed a two-stage pimple patch set with an array of tiny spikes that grabs onto the pimple and delivers antibacterial or anti-inflammatory compounds. Human clinical trials confirmed that the pimples disappeared after seven days of treatment.
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Tiny ocean partnership between algae and bacteria reveals secrets of evolution
The microscopic alliance between algae and bacteria offers rare, step-by-step snapshots of how bacteria lose genes and adapt to increasing host dependence, a new study shows.