All articles by Linda Stewart – Page 4
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Study validates DenovAI’s platform for programmable de novo-designed protein therapeutics
Researchers introduce a new class of experimentally validated AI-driven protein design tools that have the potential to accelerate drug development.
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Paper-based devices diagnose malaria in asymptomatic people
Devices made with cheap strips of paper have outperformed two other testing methods in detecting malaria infection in asymptomatic people in Ghana – a diagnostic advance that could accelerate efforts to eliminate the disease, researchers say.
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Scientists team up to identify infectious diseases using AI and hyperspectral imaging
A collaboration will expand patented technology to detect viral signatures in animals. ESS Protect – Animal will offer rapid, non-invasive, and contactless screening for bovine respiratory disease (BRD) using hyperspectral imaging and advanced machine learning.
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Illuminated changes: Enhancing D-lactic acid output with UV irradiation
Researchers have developed a Komagataella phaffii (K. phaffii) yeast strain that can efficiently produce D-lactic acid, a raw material for pharmaceuticals and bioplastics, from methanol.
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Immune tolerance to gut microbes is initiated by a key bacterial sensor
A study has found that the body’s immune “tolerance” to gut microbes depends on an ancient bacterial-sensing protein called STING—normally considered a trigger for inflammation.
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AI could accelerate protein engineering – key for developing new medicines
An AI approach developed by researchers from the University of Sheffield and AstraZeneca could make it easier to design proteins needed for new treatments.
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Scientists decipher HIV-1 transcription initiation and elongation from single-molecule imaging data
Scientists have developed a dual-driven framework based on single-molecule imaging data and stochastic dynamic modeling to infer HIV-1 transcription dynamics.
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Launch of first-in-human clinical trial of next-generation rotavirus vaccine delivered via dissolvable microarray technology
Scientists have announced the first clinical trial of a novel rotavirus vaccine, CC24, delivered via dissolvable microarray technology, is now enrolling participants.
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Excessive use of disinfectants in intensive care patients may increase the risk of antibiotic-resistant infections
An international study has, for the first time, revealed a strong and direct link between the rise of antibiotic-resistant bacteria and universal disinfection procedures applied to patients in intensive care units.
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AFYREN begins new phase of industrial strategy as first plant AFYREN NEOXY achieves continuous production
Greentech company AFYREN offering industrial customers bio-based, low-carbon products through fermentation technology based on a circular model, announced its first plant has achieved continuous production, enabling acceleration of commercialization.
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Gut microbes may help in recognizing and treating pancreatic cancer
A new international cooperation study indicates that in the future pancreatic cancer may be detected at an early stage with the help of gut microbes. Gut microbes may also offer solutions for therapy development.
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Study highlights role of jaundice-associated pigment in protecting against malaria
New research suggests that a pigment that causes yellowing of the skin, or jaundice, may help protect people from the most severe consequences of malaria.
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Broad-spectrum coronavirus drug developed through AI-enabled dynamic modeling
Multidisciplinary AI- and physics-driven modeling of the viral fusion process enables discovery of an orally available drug inhibiting infection with multiple coronaviruses.
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Scientists discover the ‘ticking’ mechanism driving nature’s simplest circadian clock
Researchers have uncovered the molecular mechanism that drives the ’ticking’ of the circadian clock in cyanobacteria. A clock protein called KaiC controls chemical reactions with precision, acting like the hand of a clock that waits, then moves at just the right moment.
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Researchers discover protein necessary for SARS-CoV-2 to evade the body’s defenses
Researchers have identified a protein that plays a key role in helping SARS-CoV-2 hide from the body’s defenses by suppressing the production of viral double-stranded (dsRNA), leading to increased viral replication while limiting the body’s immune response.
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Northward jet stream shift hits phytoplankton in the Mediterranean Sea
In just over 20 years, the northward shift of the subtropical jet stream — a high-altitude airflow — caused by climate change has reduced primary production in the northwestern Mediterranean by about 40%, affecting the base of the marine food web.
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Evolutionary model for antibiotic resistance reveals dose timing critical to care
The study that uses a “fitness seascape” to incorporate a patient’s dosage schedule into models that predict whether an infection will develop antibiotic resistance has found that inconsistent timing and missing early doses can lead to treatment failure.
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Microbiome stability shapes how corals withstand extreme heat
A new study reveals why some corals resist bleaching while others don’t: the answer lies in a complex partnership between corals and their microbial allies, shaped by the history of the waters they inhabit.
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Oxymatrine, a quinoline alkaloid derived from Sophora flavescens, inhibits the Malassezia biofilm
Oxymatrine not only controls Malassezia overgrowth but also manages psoriasis symptoms, offering a dual-action mechanism for safer and more effective therapy, a new study shows.
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Scientists develop a treatment platform to disable the ‘biofilm’ shield of superbugs
Researchers have developed a platform that utilizes microbubbles to deliver gene-targeted nanoparticles capable of breaking down MRSA biofilms, offering an innovative solution for treating infections resistant to conventional antibiotics.