All articles by Linda Stewart – Page 8
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NewsReconstructing nature’s oxindole factory: yeast-based biosynthesis of medicinal indole alkaloids
By identifying four key enzymes from a North American plant and reconstituting them in yeast, scientists have achieved complete de novo biosynthesis of complex oxindole molecules that are difficult to obtain from plants or chemical synthesis.
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NewsValneva provides update on Chikungunya vaccine IXCHIQ®
Valneva SE has announced that the company has decided to voluntarily withdraw the biologics license application (BLA) and Investigational New Drug (IND) application for its chikungunya vaccine, IXCHIQ® , in the United States, following suspension of the license by the FDA.
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NewsEngineered yeast delivers record levels of animal-free chondroitin sulfate
A new study establishes a robust yeast-based platform that overcomes the long-standing trade-off between yield and sulfation, enabling sustainable, high-level production of high-quality chondroitin sulfate without reliance on animal sources.
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NewsShingles vaccine linked to slower biological aging in older adults
Shingles vaccination not only protects against the disease but may also contribute to slower biological aging in older adults, according to a new study.
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NewsEngineering yeast to make rare anticancer saponins: reconstructing the complete biosynthesis of polyphyllin II
By combining plant transcriptomics, enzyme engineering, and synthetic biology, a new study demonstrates, for the first time, the full heterologous production of polyphyllin II in Saccharomyces cerevisiae.
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News58% of patients affected by 2022 mpox outbreak report lasting physical symptoms
A cohort study found that more than half of those diagnosed with mpox during the 2022 outbreak still had lingering physical effects 11 to 18 months later.
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NewsScientists develop new biosynthetic route to optically pure S-2-Hydroxyisovalerate
By uncovering an unexpected enzyme activity and combining it with precise metabolic engineering, scientists has transformed Escherichia coli into a microbial factory capable of producing gram-per-liter levels of optically pure S-HIV from renewable carbon sources.
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NewsAltered microbiome: Oral bacteria play a role in chronic liver disease
A new study shows that identical bacterial strains occur in both the mouth and gut of patients with advanced chronic liver disease and also reveals a mechanism by which oral bacteria affect gut health. The researchers also found that this process coincides with worsening liver health.
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NewsScientists find new way to disarm antibiotic-resistant bacteria and restore healing in chronic wounds
Scientists have discovered a new way that could speed up the healing of chronic wounds infected by antibiotic-resistant bacteria. The study shows how a common bacterium, Enterococcus faecalis (E. faecalis), actively prevents wound healing.
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NewsPregnant women hospitalized for COVID-19, and their newborns, have higher complication risk
When hospitalized for COVID-19, pregnant women — and their eventual newborn children — have a higher risk of complications. Research revealed that pregnant women were nearly 3.5 times more likely than non-pregnant women to require respiratory support when hospitalized for COVID-19.
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NewsDeadly to amphibians, a fungal strain emerged in Brazil and spread around the world
The fungal infection Batrachochytrium dendrobatidis is responsible for the decline of toad and frog populations across the globe. A new study has pinpointed the origin of the fungal strain.
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NewsResearchers discover how a respiratory bacterium obtains essential lipids from the human body and targets fat-rich tissues
A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae—responsible for atypical pneumonia and other respiratory infections—to obtain cholesterol and other essential lipids directly from the human body.
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NewsBat virome evolution reveals cross-species origins of porcine epidemic diarrhea virus and regional surveillance gaps
A study has unveiled the Indochina Peninsula’s bat virome diversity, offering key insights into the origins of porcine epidemic diarrhea virus (PEDV) and critical surveillance priorities.
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NewsExploring metabolic noise opens new paths to better biomanufacturing
Engineers investigating fluctuating metabolic activity in microorganisms have developed tools to keep every microbial cell at peak productivity during biomanufacturing.
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NewsBacterial energy model reveals how antimicrobial resistance (AMR) spreads in environment
Researchers analyzed how bacteria in aquatic environments distribute energy across diverse functions such as growth, biofilm formation, conjugative transfer of antimicrobial resistance genes and heavy‑metal tolerance, to clarify bacterial energy investment strategies.
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NewsProject to combat childhood diarrhea receives over 5 million euros
A new project will use probiotics, improved education in hygiene and advanced mathematical models to prevent children from dying of diarrhea in low and middle-income countries.
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NewsEarly intervention of cyanobacterial risks starting from the genome?
A new study proposes using “~3 Mbp” as a threshold to establish a genome size-oriented proxy indicator for cyanobacterial risk early warning.
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NewsLiquorice root could be effective against upper respiratory tract infections - while protecting ‘good’ microbes
Lozenges supplemented with liquorice root extract could be an effective remedy against upper respiratory tract infections while protecting microbes that are beneficial to the body, reveals a study presented at MLS Future Forum, which is supported by Applied Microbiology International.
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NewsScientists explore how gut bacteria alter the flavor of Black Ivory coffee beans
Coffee beans that pass through the digestive tracts of animals get their unique flavors from the activity of gut microbes, report researchers. Bacterial activity that reduces the pectin content of Black Ivory coffee could be the source of its smoother, chocolaty, and less bitter flavor.
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NewsCommercial water dispenser machines may contain more contamination than tap water
Water dispenser machines in commercial spaces may contain higher levels of microbial contamination if they aren’t cleaned regularly compared to the tap water sources supplying them that contain residual chlorine, according to a new study.