All mandimycin M16 articles
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NewsNew architecture for antifungal drug precisely combats fungal infections in mice without the usual toxicity
By applying a unique molecular “scaffold,” researchers have created a broad-spectrum antifungal drug that homes in on a key fungal compound without disrupting the host’s cholesterol – a frequent side effect of current therapies. The compound’s selectivity could help avoid the toxic side effects that have plagued antifungal therapy regimens for decades.