All Microbiological Methods articles – Page 3
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Viruses under the super microscope: How influenza viruses communicate with cells
Scientists have characterized a new model of influenza A infection: binding to MHC class II complexes as an alternative receptor and the associated dynamic reorganization of the cell surface.
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High-density screening technique reveals key genes for biotechnology improvements
Scientists used a gene-silencing tool and molecular guides to probe how photosynthetic bacteria adapt to light and temperature changes, finding even partial suppression of certain genes yielded big benefits in modifying the stress response of wild microbes.
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AI plays detective to help scientists find hidden microbes
A team of researchers has created a novel machine learning tool that’s cracking open one of biology’s trickiest puzzles: finding the rarest microbes on Earth. Ulrb not only identifies rare microorganisms but also works with non-microbial data.
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Placebo-testing vaccines is unethical, ‘a waste of time and money,’ expert says
The proposal to require that all new vaccines undergo safety testing in placebo-controlled trials is ethically problematic and will slow testing down for no good reason, warn scientists.
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Bacteria deployed as living test tubes to study human gene mutations
Bioengineers have developed a new simple approach to rapidly check on human gene changes and also screen chemicals as potential drugs by turning everyday bacteria into living test tubes.
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New AI technique can uncover antiviral compounds using limited data
Artificial intelligence algorithms have been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease.
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Scientists repurpose gene editing tool to help uncover hidden microbial diversity
Pioneering research has repurposed a gene editing tool to help shed light on the true biodiversity present in natural environments. The study could help pave the way for more productive soils and improved health.
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No more copy-pasting: DNA base editing for better Lactobacillus strains
Scientists were able to edit the DNA of Lactobacillus strains directly without a template from other organisms. This technique is indistinguishable from natural variation and enabled them to create a strain that doesn’t produce diabetes-aggravating chemicals.
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Open benchmarking of CycloneSeq™ for complete bacterial genomes
Benchmark data and analysis of new CycloneSEQ using novel nanopore sequencing technology demonstrates the ability to sequence complete bacterial genomes.
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Infectious disease surveillance platform BEACON launches as a new open-source global resource
The Biothreats Emergence, Analysis and Communications Network (BEACON), an open-source infectious diseases monitoring tool powered by AI and human experts, has been launched.
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The very first structural images of a tuberculosis-fighting virus
Scientists have used advanced imaging techniques to provide a detailed look at how a tiny virus, known as a phage, invades Mycobacteria. The research could pave the way toward phage-based treatments for antibiotic-resistant mycobacteria.
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Researchers develop UV and machine learning-aided method to detect microbial contamination in cell cultures
This is the first novel technology that utilises machine learning to analyse unique ultraviolet light “fingerprints” on cell cultures to quickly identify the presence of contamination.
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New tool for cutting DNA offers promising prospects for biotechnology
Researchers have developed a new genetic tool based on a family of specific enzymes called Ssn that allows targeted cuts to be induced exclusively in single-stranded DNA. They focused on one of these enzymes in the bacterium Neisseria meningitidis.
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New platform leverages AI and quantum computing to predict salmonella antimicrobial resistance
A recent study presents a novel approach to predict Salmonella antimicrobial resistance, a growing concern for public health. The research combines large language models (LLMs) and quantum computing to develop a predictive platform.
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Scientists develop special agar for isolation of Escherichia albertii and its evaluation with food samples
Scientists have developed a novel E. albertii selective differential medium, XRM-MacConkey medium containing cefixime, tellurite, phosphate, and soy peptone, which differentiates E. albertii (colorless) from E. coli (red) by colony color.
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Microscopy reveals signs of life in earth’s extremes, boosting search for alien life
Researchers used advanced microscopy to detect microbial biosignatures that help to identify the signs of life in extreme environments on Earth, thus also applicable in the search of life in extraterrestial environments.
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Singapore launches national standard to validate antimicrobial disinfectant products
SS 705 provides a first-of-its-kind Singapore-developed assessment to test the effectiveness of antibacterial, antifungal and antiviral potency, as well as durability of surface disinfectants and coatings.
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Hidden signals in water reveal disease early in tomato plants
Researchers have developed an innovative method for the early detection of Fusarium wilt in tomato plants by monitoring subtle changes in the plants’ water use.
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Rice research team creates universal RNA barcoding system for tracking gene transfer in bacteria
An interdisciplinary group of researchers at Rice University has developed an innovative RNA “barcoding” method to track gene transfer in microbial communities, providing new insights into how genes move across species.
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New method uncovers dynamic microbial community in coastal sediments
Scientists utilises single celll genomics and cell staining approaches to investigate the respiratory rates and metabolic activities of the diverse microbial communities in low biomass aqautic environments, such as Maine’s coastal sediments.