All Microbiological Methods articles – Page 3
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NewsSeawater microbes offer new, non-invasive way to detect coral disease, study finds
Researchers have discovered that microorganisms in seawater surrounding corals provide a powerful indicator of coral disease, potentially transforming how reef health is monitored worldwide.
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NewsHuman nasal passages defend against the common cold and help determine how sick we get
Researchers demonstrate how the cells in our noses work together to defend us from the common cold and suggest that our body’s defense to rhinovirus—not the virus itself—typically predicts whether or not we catch a cold, as well as how bad our symptoms will be.
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NewsGolden Gate method enables rapid, fully-synthetic engineering of therapeutically relevant bacteriophages
Researchers have described the first fully synthetic bacteriophage engineering system for Pseudomonas aeruginosa. In this method, researchers engineer bacteriophages synthetically using sequence data rather than bacteriophage isolates.
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NewsExploring metabolic noise opens new paths to better biomanufacturing
Engineers investigating fluctuating metabolic activity in microorganisms have developed tools to keep every microbial cell at peak productivity during biomanufacturing.
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NewsEarly intervention of cyanobacterial risks starting from the genome?
A new study proposes using “~3 Mbp” as a threshold to establish a genome size-oriented proxy indicator for cyanobacterial risk early warning.
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NewsNew study explores therapeutic potential of CRISPRCas3 genome-editing system
Scientists working on the genetic disease transthyretin amyloidosis evaluated the efficacy of the CRISPR–Cas3 system in safely achieving a permanent reduction of transthyretin (TTR) production through genome editing of the TTR gene.
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NewsBirding enthusiasts can help songbirds avoid salmonella epidemics
Biologists are developing a tool to predict when deadly salmonella outbreaks are likely to happen in wild songbird populations so that people can protect their feathered friends by taking down bird feeders at the right time.
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NewsA gentler way to model deadly lung infections in old age
Researchers report a refined mouse model that successfully mimics chronic Pseudomonas aeruginosa lung infection in old age. The study introduces an agar bead-based delivery strategy that allows bacteria to persist in the lungs of aged mice without causing rapid death.
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NewsFrom palm oil to designer enzymes: researchers reprogram yeast cells
Many everyday products contain fatty acids from palm oil or coconut oil, but the extraction of these raw materials is associated with massive environmental issues. Researchers have now developed a biotechnological approach that could enable a more environmentally friendly production method.
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NewsChanges in genetic structure of yeast lead to disease-causing genomic instabilities
Researchers studying a yeast model have discovered that the loss of heterochromatin can kickstart genetic changes, potentially resulting in the development of diseases like cancer.
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NewsNew test shows which antibiotics actually work
Drugs that act against bacteria are mainly assessed based on how well they inhibit bacterial growth under laboratory conditions. A critical factor is whether the active substances actually kill the pathogens in the body. Researchers have presented a new method for measuring how effectively antibiotics kill bacteria.
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NewsNew biosensor technology could transform how viruses are detected
A new review highlights major advances in a promising class of diagnostic tools known as aptamer-based biosensors, which could help deliver faster, cheaper, and more portable virus testing in clinics, communities, and the field.
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NewsFrom sediment to surface: How invisible plumes trigger harmful algal blooms
A new study shows that algal blooms can begin days earlier than previously recognized, originating from chlorophyll-rich plumes rising from lake sediments before any surface discoloration appears.
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NewsA practical guide for characterization of novel CRISPR-Cas systems with Pro-CRISPR factors
In this protocol, the authors provide a method encompassing protein purification, biochemical characterization, validation of protein-protein interactions, and preliminary in vivo functional assays in bacteria for Cas nuclease and its associated Pro-CRISPR factor.
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NewsFiltering the invisible: New evidence points to more efficient indoor air microbe sampling
Using fluorescence-based detection, a new study provides clear, quantitative evidence that sampling principle, collection medium, and airflow rate strongly shape how well indoor microbial aerosols can be measured.
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NewsHarnessing the positive health benefits of microbes
A new article introduces the ‘Database of Salutogenic Potential’, a world-first prototype open-access repository that catalogues microbes and natural compounds linked to positive health outcomes.
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NewsA ‘one-pot’ assay of or rapid portable identification of genotypes I and II African swine fever viruses
Researchers in search of an African swine fever virus genotyping method developed an isothermal ‘one-pot’ CRISPR-Cas12i3/Cas13d-based assay, designated OBServe.v2, to detect two amplified targets from multiplex recombinase polymerase amplification (RPA) in a single tube.
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NewsBreakthrough AI speeds up discovery of life-supporting microbes
Scientists have developed a powerful new artificial intelligence tool called LA⁴SR that can rapidly identify previously overlooked proteins in microalgae - tiny organisms that produce much of the Earth’s oxygen and support entire aquatic ecosystems.
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NewsSmarter tools for peering into the microscopic world
In a pair of new studies, researchers introduce powerful tools that make it easier, more accurate and more scalable to figure out how microbes are related. One tool improves how scientists build microbial family trees. The other provides a software foundation used worldwide to analyze biological data.
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NewsFecal tests reveal active termite attacks
Termite pellets can linger long after the insects that dropped them have disappeared. By testing for microbes in the excrement, researchers can distinguish old droppings from fresh, and whether a colony is actively chewing its way through a home.