All Microbiological Methods articles
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NewsDirect rescue of segmented negative-sense RNA viruses from complementary DNA in monkey kidney Vero cells
This technology enables the direct rescue of segmented negative-sense RNA viruses from complementary DNA in monkey kidney Vero cells, facilitating safer and more efficient live-attenuated vaccine production.
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NewsScientists reveal tissue culture-free (“ex vitro”) transformation method for trees
This technology introduces a novel “ex vitro” transformation method that utilizes Agrobacterium rhizogenes to genetically modify the roots of woody plants without the necessity for tissue culture.
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NewsNabsys announces first publication showcasing CRISPR/Cas9 mediated approach to expand the capabilities of electronic genome mapping
This study is the first to demonstrate the potential of combining Electronic Genome Mapping (EGM) with CRISPR/Cas9 to both characterize CRISPR/Cas9 activity and enhance the capabilities of genome mapping.
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NewsNew standardised, contemporary strain panels address a long-standing barrier in AMR research
PACE and the UK Health Security Agency have released five new contemporary antimicrobial resistance (AMR) strain panels, giving innovators worldwide a resource to test novel therapeutics and diagnostics against today’s resistance patterns.
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NewsNovel database reveals hidden diversity and potential of deep-sea microbes
Scientists have spearheaded Global Ocean Reference Genomes Dark (GORG-Dark), the first global atlas of single-cell microbes living in the aphotic ocean. It contains more than 9,600 genomes from individual microbial cells collected across a broad range of depths and locations, including the Mariana Trench and the Antarctic.
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NewsAn IBEC device simulates natural conditions to grow biofilms and test their antibiotic susceptibility more accurately
Researchers have developed XpertBiofilm, a simple and accessible device that allows biofilms to be grown under continuous, controlled liquid flow, similar to what bacteria encounter in the human body — for example, in lung mucus, blood or urine.
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NewsBreakthrough optimization of chlamydospore fermentation for Cladophialophora guangxiense HX2
The dark septate endophyte Cladophialophora guangxiense HX2 exhibits excellent control efficacy against tomato bacterial wilt but industrial production of its chlamydospores has been challenging. Researchers have optimized the liquid fermentation process using chlamydospore yield of strain HX2 as the key response indicator.
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NewsMosquito waste reveals viruses hiding in plain sight
When public health researchers want to know whether diseases such as COVID-19 or polio are circulating in a community, they can look for genetic evidence in wastewater. Source: Dana Price/Rutgers University Dana Price of the Rutgers Center for Vector Biology sets a mosquito-waste collection trap in the field ...
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NewsMajor investment to unlock the potential of protist research
A new collaboration will tackle major technical challenges currently limiting protist genomics, helping to unlock the potential of protist research for biomanufacturing, sustainable agriculture and environmental applications.
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NewsNew research offers avenue to explore relationship between Alzheimer’s and HIV
Researchers have created an animal model that helps resolve questions about the relationship between HIV and Alzheimer’s disease (AD). The virus that drives the root cause of AD initiates a complex chain that, with other disease partners, drives nerve cell injury and cognitive impairments for AD pathology.
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NewsSuper-resolution imaging reveals details inside living cells
A new fluorescence microscopy technique that generates super-resolution images from a single camera exposure could help researchers study rapid movements within cells that are difficult to capture with existing methods.
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NewsMicro-bladder model offers clues to stopping recurrent UTIs
A new study shows that phage therapy – the use of tiny viruses to kill bacteria without harming people – could help to reduce recurrent infections, which happen when the bacteria responsible for UTIs ‘hide’ in the tissue of the bladder.
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NewsAncient Dujiangyan water wisdom inspires AI microfluidic chip to spot hidden sub-resistant bacteria
To pinpoint hidden populations of bacteria, researchers have developed a deep learning-based microfluidic rapid phenotypic AST system, named DP-AST, inspired by the “six-four water diversion” principle of the ancient Dujiangyan irrigation system in China.
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NewsNew water freeze-drying sample preparation method allows for the capture of a near-native ultrastructure of bacteria
A collaborative research team has successfully applied Water Freeze-Drying method to bacterial specimens, allowing them to capture the ultrastructure of bacteria in near-native form via scanning electron microscopy.
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NewsBeyond COVID-19: Fundamental principles that shape pandemics
Researchers have compiled 10 fundamental mechanisms that can be used to describe the development of pandemics, bringing together insights from epidemiology, sociology, mathematics, physics, political science, psychology, and public health.
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NewsMachine learning turns routine water quality data into early warnings for pathogen health risks
Researchers have developed a data-driven framework that uses routinely measured water quality indicators to predict pathogen concentrations and estimate their potential health risks.
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NewsWidely used early warning score may help guide the urgency of antibiotic treatment for suspected sepsis
Large cohort study suggests the National Early Warning Score (NEWS2) may provide a more comprehensive framework than current guidance for determining which patients with suspected sepsis benefit from immediate antibiotics.
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NewsDecoding the gut microbiome’s symphony in health and disease
Researchers have reported effective strategies for simultaneously measuring thousands of microbial and host proteins. They systematically compared five state-of-the-art mass spectrometry approaches using human fecal samples.
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NewsBloomNet turns lake data into early algal bloom warnings
A research team has developed BloomNet, an interpretable deep-learning framework that forecasts harmful algal blooms at hourly resolution up to 72 hours ahead while also showing how risk changes over time.
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NewsThe hepatitis E virus cannot infect mice - and here’s why
It has long been known that the hepatitis E virus cannot establish an infection in mice, but the reasons were unknown. Scientists have therefore systematically examined the replication cycle of the virus in liver cell cultures of mice.