More News – Page 17
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NewsResearchers discover how to turn one germ’s drug resistance into an Achilles’ heel
As Mycobacterium tuberculosis mutates to protect itself from rifampicin, it also creates new weak points that other therapies could exploit. A new study shows that the most common rifampicin-resistance mutation slows bacterial RNA polymerase, creating vulnerabilities that future combination therapies may be able to target.
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NewsThe brain, emotions, and the gut: How culture, stress, and social life shape gut health
A new study indicates that gastrointestinal health is influenced not only by genes, diet, and gut bacteria, but also by culture, social relationships, economic status, and the way individuals function within society.
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NewsThe right heat makes biochar a better helper for food waste composting
A new study finds that hardwood biochar made at 400 °C best protects nitrogen during food waste digestate composting, offering a practical route to cleaner and higher-quality compost.
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NewsGladstone launches Center for PhAIge Therapy to harness AI in the fight against drug-resistant infections
Gladstone Institutes has received funding to establish the Center for PhAIge Therapy, a research center that will develop new phage-based treatments for antibiotic-resistant bacterial infections. The five-year grant makes Gladstone one of three institutions across the country selected to lead this coordinated effort.
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NewsT cells may be key to stopping measles virus—and its deadly relatives
Scientists have discovered how T cells target paramyxoviruses, a viral family that includes measles virus and Nipah virus. Instead of vaccinating against one virus at a time, the researchers found that activating “cross-reactive” T cells may protect against the wider paramyxovirus family.
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NewsScientists recreate enterovirus infection in a new model of the human intestine
A miniaturized, biomimetic model of the human intestine successfully reproduced long-term enterovirus A71 (EV-A71) infection, report researchers. Using this innovative platform, they shed light on how this virus grows in the intestine without triggering a strong immune response.
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NewsPopular GLP-1 drug may slow down biological aging in people with HIV
A new study provides the first randomized, placebo-controlled clinical evidence that semaglutide, a widely used GLP-1 drug, slows down the accumulation of biological aging markers in the DNA of adults with HIV.
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NewsBiomaterial made from jackfruit latex is a promising treatment for periodontitis
Researchers have developed a biomaterial containing jackfruit latex, pomegranate peel extract, and simvastatin that shows promising efficacy in treating periodontitis. This chronic inflammatory disease of infectious origin leads to the progressive destruction of the tissues supporting the teeth, resulting in bone resorption and loss of attachment.
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NewsStudy identifies serious infection risks linked to targeted cancer therapies
A major real-world study has found serious blood-related side effects associated with antibody-drug conjugates, an increasingly important class of targeted cancer therapies. Some ADCs were associated with substantial rates of severe neutropenia – dangerously low levels of infection-fighting white blood cells – and related complications.
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NewsMagnetic biochar gel helps keep arsenic and antimony out of rice
A new study reports a promising strategy for mining-impacted regions: a magnetic silicon-enriched biochar gel that can immobilize both arsenic and antimony in contaminated paddy soil and reduce their accumulation in rice grains.
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NewsPhase 1 clinical trial set to begin on first leishmaniasis vaccine
A phase 1 clinical trial testing the safety of a leishmaniasis vaccine is set to begin in the coming months. The live vaccine, found to be safe in animals, is expected to be tested in humans later this year.
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NewsResearchers evaluate NASA medication storage protocols
Researchers evaluated NASA’s medication handling practices, which currently call for removing medications from their original packaging and storing them in resealable plastic bags. The investigation found that active pharmaceutical ingredients degrade at a higher rate when stored in bags.
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NewsNew study identifies key warning signs for infection after ankle fracture surgery in older patients
A new study of which patients are most at risk of a fracture-related infection post ankle surgery finds that low protein levels in the blood is the single strongest patient-related risk factor, making infection nearly 18 times more likely. Chronic alcohol abuse and failure to follow post-operative instructions each raise the risk more than fivefold.
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NewsZinc deficiency promotes fluconazole-resistant Candida auris virulence
Researchers identified key nutritional and genetic factors that drive the virulence of fluconazole-resistant Candida auris. Under zinc-deficient conditions, these drug-resistant strains gain a fitness advantage, exhibiting increased pathogenicity and resistance to macrophage-mediated killing.
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NewsHow Chinese cabbage fights downy mildew
Researchers focusing on the Brassica rapa–Hyaloperonospora parasitica pathosystem identifies DM459 as an Arg–x–Leu–Arg (RXLR) effector that interacts with BraATG8i, activates autophagy, stimulates salicylic acid (SA) signaling, and enhances resistance to downy mildew.
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NewsNew study uncovers why the Arctic’s rivers are rusting
Scientists have identified the two biggest reasons that once-pristine rivers across the Arctic are growing cloudy with toxic orange iron particles that smother insects and suffocate fish. As the climate warms, a layer of Arctic soil that had been frozen for millennia has begun to thaw.
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News‘Accidental’ discovery lays foundation for novel flu treatment strategies
Scientists investigating how influenza viruses replicate within cells “accidentally” discovered that different flu viruses use distinct strategies to infiltrate cells in the first place. They also found that it is possible to target specific molecules to prevent the viruses from entering new cells, thereby stopping their replication.
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NewsEU project aims to make climate-neutral plastics and cosmetics using bacteria
A European research team is aiming to revolutionize the chemical industry: as part of the CarboNcare project, scientists are developing bacteria that can produce important chemical base materials from sustainable methanol – thereby replacing fossil resources.
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NewsEngineered gut bacteria therapy emerges as scalable potential alternative to fecal microbiota transplants following clinical trial
Researchers have developed a new manufacturing platform for producing targeted mixtures of beneficial gut bacteria, an approach that could help expand access to microbiome-based therapies for patients with recurrent Clostridioides difficile (C. difficile) infection.
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NewsReal-time brain monitor detects infections earlier
A research team has created a new monitoring system to save lives and significantly reduce health-care costs in brain-injury cases through the early detection of infections in intensive care units. NeuroSense connects to drainage lines to detect biomarkers of infection.