All Patrick Tan articles
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News
Scientists link waning Japanese encephalitis immunity to higher dengue severity
Scientists have found that waning immunity to Japanese encephalitis virus (JEV) may increase the risk of more severe dengue disease in humans. The study highlights how fading vaccine protection from one virus can unintentionally affect the body’s response to another.
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Scientists reveal gut microbes’ hidden role in anxiety—Could probiotics be the next mental health breakthrough?
Scientists have discovered a crucial connection between gut microbes and anxiety-related behaviour, suggesting that microbial metabolites – specifically indoles – play a direct role in regulating brain activity linked to anxiety.
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T cells’ capability to fully prevent acute viral infections opens new avenues for vaccine development
Scientists have discovered that T cells—white blood cells that can destroy harmful pathogens—can completely prevent viral infection, to an extent previously thought only possible due to neutralising antibodies.
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Study reveals early immune protection in the womb
Researchers have discovered that fetuses can manage their own immune responses to combat diseases and infections like Zika.
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Immune response to dengue can predict risk of severe reinfections
Researchers have found that natural killer T (NKT) cells influence whether the immune response generates protective antibodies that neutralise dengue virus or harmful ones that could exacerbate the disease in future infections.
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Zika virus vaccine emerges as an unlikely hero in battling brain cancer
Scientists have developed a new approach using the Zika virus to destroy brain cancer cells and inhibit tumour growth, while sparing healthy cells.
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Potential nasal COVID-19 vaccine candidate offers better and longer protection
Study shows that administering a COVID-19 vaccine as a nasal spray rather than a subcutaneous injection enhances the body’s long-term immune memory, thereby increasing the vaccine’s overall effectiveness.
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Maternal dengue immunity worsens birth defects caused by Zika virus
A new study finds prior dengue antibodies substantially raise the risk of microcephaly and fetal defects with Zika infection.
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New strains of influenza A virus in pigs potentially pose pandemic risk
A new study addresses gaps in understanding of swine influenza A virus evolution and highlights need for early warning of disease emergence.
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Newly discovered antibodies can neutralize COVID-19 variants
Scientists have isolated potent neutralizing antibodies from a COVID-19 vaccinated SARS survivor that exhibited remarkable breadth against known sarbecoviruses.