All Phage Therapy articles – Page 3
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NewsHuman clinical study launched using phage lysin to eliminate staph in the nasal microbiome
A “first-in-human” study with the novel drug candidate HY-133 began on 10 July with the recruitment of clinically healthy volunteers who tested positive for Staphylococcus aureus colonisation of the nose.
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NewsResearchers unveil secrets behind phages’ flawless timing
New research is shedding light on how viruses ensure their survival by precisely timing the release of new viruses. The discovery offers a new theoretical framework for understanding these dynamic biological phenomena.
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NewsHarnessing big data helps scientists hone in on new antimicrobials
Scientists have detailed a new method of identifying antimicrobial enzymes from large datasets of bacterial proteins, which could provide a solution to antibiotic resistance.
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NewsResearchers develop a way to make lifesaving phages accessible, transportable and much easier to use
Researchers have developed a simple new way to store, identify, and share phages, making them more accessible to patients who need them.
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NewsPhage-derived enzyme targets biofilms to mitigate acute graft-versus-host disease
Scientists investigating acute graft-versus-host disease probe gut microbiome to detect presence of a bacteriophage-derived enzyme known as endolysin, exhibiting potent antibacterial activity specifically targeting E. faecalis.
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News‘Sacrifice’ of virus data clears the path to open a disease discovery pipeline
Researchers are analysing viruses in human populations – and on coral reefs – to build a robust method of identifying viruses in all animals, plants and environments, and to show the flexibility of the pipeline for future research.
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NewsPhage‐display tech boosts targeting ability of antimicrobial peptides against Staphylococcus aureus
Antibiotics are widely used in clinical treatment and animal production as an effective means to combat microbial infections. Antimicrobial peptides, as potential alternatives to antibiotics, have shown promising applications. Source: CDC/ Matthew J. Arduino/ Janice Haney Carr Under a very high magnification of 20,000x, this scanning electron micrograph ...
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CareersA day in the life of a phage expert
Nicolás Cifuentes is Head of Research Projects and Phages at PhageLab, Chile, which offers tailor-made solutions to control bacterial outbreaks in the livestock and poultry industries.
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NewsPlant bacteria deploy phage elements to wipe out the competition
A new study has found that plant bacterial pathogens are able to repurpose elements of their own phages to wipe out competing microbes, suggesting such elements could someday be harnessed as an alternative to antibiotics.
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NewsMalta hosts groundbreaking 7th World Conference on Targeting Phage Therapy 2024
The historic Corinthia Palace in Malta is set to host the 7th World Conference on Targeting Phage Therapy on June 20-21, 2024. This event will bring together the world’s foremost leaders and researchers in bacteriophage therapy, highlighting the growing importance and global interest in this innovative field. ...
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NewsInnovative phage lysin HY-133 enters phase I clinical study
HYpharm’s innovative preventive agent HY-133 has reached the first clinical trial phase. HY-133 is specifically effective against Staphylococcus aureus including multi-resistant strains and is intended to combat its colonisation in the nose.
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NewsSqueaks the cat makes full recovery after personalized phage therapy heals resistant wounds
A new study highlights the potential of phage therapy as an effective solution for antibiotic-resistant infections in veterinary practice, resulting in the complete healing of a persistent surgical wound after fourteen weeks.
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NewsVirocells: How the ‘home’ environment influences microbial interactions
Research into ocean virocells - bacteria infected by viruses, thus forming a new organism - has yielded fascinating new insights about how this merger of microbes affects, and is affected by, real-world surroundings.
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NewsSea zombies: Viruses keep the most common marine bacteria in check
The ocean waters surrounding the German island of Helgoland provide an ideal setting to study spring algae blooms, a focus of research at the Max Planck Institute for Marine Microbiology since 2009. Source: Jan Brüwer/Max Planck Institute for Marine Microbiology Sunset over the island of Helgoland in ...
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NewsStudy provides new insights into phage therapy design
Results from a new study are providing new insights into the therapeutic potential of bacteriophage (phage) therapy for treating diseases like cystic fibrosis (CF).
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NewsBiophysicist F. William Studier awarded Merkin prize in biomedical technology
F. William Studier, a senior biophysicist emeritus at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory, has won the 2024 Richard N. Merkin Prize in Biomedical Technology for his development in the 1980s of an efficient, scalable method of producing RNA and proteins in the laboratory. Source: ...
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NewsA new acquired defense strategy different from CRISPR activates anti-mycobacteriophage immunity
A new study suggests endogenous insertion sequences (ISs) in mycobacteria can activate the defensive gene islands, thereby helping bacteria quickly acquire a broad-spectrum anti-phage ability.
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NewsResearchers discover key functions of therapeutically promising jumbo viruses
Identifying core replication processes has moved scientists closer to tapping phage as a treatment in the growing antibiotic resistance crisis.
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NewsA virus could help save billions of gallons of wastewater produced by fracking
A new study details how bacteriophages, viruses that are often highly specific and lethal to a single species of bacteria, can be used as a rapid and cost-effective method to treat produced water on an industrial scale.
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NewsScientists reveal interaction mechanism between intestinal microbial environment and tumor immune microenvironment
Scientists have unveiled the mechanism of tumor immune evasion mediated by the microorganism C. scindens in colorectal cancer. Additionally, they developed a phage-based intervention method.