All Phage Therapy articles – Page 4
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NewsStudy details a common bacterial defense against viral infection
One of the many secrets to bacteria’s success is their ability to defend themselves from viruses, called phages, that infect bacteria and use their cellular machinery to make copies of themselves. Source: Mogana Das Murtey and Patchamuthu Ramasamy Bacillus cereus, SEM image Technological advances have enabled recent ...
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NewsExperts developing way to harness Nobel Prize winning CRISPR technology to deal with antimicrobial resistance (AMR)
Scientists show how the latest CRISPR-Cas gene editing technology can be used to help modify and attack AMR bacteria.
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NewsWastewater plant yields giant viruses that infect deadly parasite
Researchers have discovered giant viruses that infect the single-celled organism Naegleria fowleri which ranks among the deadliest human parasites.
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NewsOdor-causing bacteria in armpits targeted using bacteriophage-derived lysin
Researchers analyzed bacterial metabolism and the DNA of skin microflora in armpit fluid samples and found odor-causing precursors along with a proliferation of Staphylococcus hominis bacteria.
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NewsGut bacteria can change their ‘software’ in reaction to inflammation
New research reveals an ingenious adaptation strategy used by gut microbes, allowing them to dynamically reprogram gene expression based on local conditions like inflammation or viral attacks.
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NewsResearchers resolve old mystery of how phages disarm pathogenic bacteria
Scientists observed how a phage called PP7 infects Pseudomonas aeruginosa by attaching to the pilus, which then retracts and pulls the phage to the cell surface.
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NewsUC San Diego donates blood samples to accelerate Actiphage TB diagnostic study
Sharing samples from a previous study will help to accelerate the development of a blood-based phage diagnostic for tuberculosis. PBD Biotech has asked if more researchers would be prepared to contribute samples they no longer require to help end TB.
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NewsScientists discover new phage resistance mechanism in phage-bacterial arms race
Sscientists exploring the complex interactions of microbes in the oral microbiome discovered a new player influencing the phage-bacterial arms race – ultrasmall bacterial parasites, called Saccharibacteria or TM7.
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NewsResearchers uncover how viruses choose whether to become nasty or not
Researchers have deciphered a novel complex decision-making process that helps viruses choose to turn nasty or stay friendly to their bacterial host.
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NewsPhage enzyme deployed against drug-resistant bacteria
Given the worldwide prevalence of drug-resistance bacteria, the research fraternity is on the lookout for alternative bactericidal treatment approaches. In a recent study, Japanese researchers have now compared bacteriophage-derived enzymes for combating drug-resistant bacteria. Source: National Institute of Allergy and Infectious Diseases (NIAID) Digitally-colorized scanning electron micrograph (SEM) ...
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NewsFirst atom-level structure of packaged viral genome reveals new properties, dynamics
A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and drug targets, researchers report.
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News‘Dynamic duo’ defences in bacteria ward off viral threats
Scientists have discovered that bacteria can pair up their defence systems to create a formidable force, greater than the sum of its parts, to fight off attack from phage viruses.
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NewsPhage therapy eradicates pan-resistant priority pathogen in vivo, study shows
A new study describes the use of phage therapy to eradicate multi-drug resistant Pseudomonas aeruginosa infections in a living organism (in vivo) with important new implications to antibiotic resistance.
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NewsEnvironmental monitoring offers low-cost phage tool for typhoid fever surveillance
Researchers can accurately track where typhoid fever cases are highest by monitoring environmental samples for bacteriophages that specifically infect the bacterium that causes typhoid fever.
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NewsDrug-resistant bacterium responds to phage-antibiotic combo therapy
A case study, which required emergency investigational new drug approval from the U.S. FDA, is one of only a handful that have used bacteriophage therapy to treat Enterococcus faecium infection.
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NewsModified phage DNA can kill deadly pathogens
DNA modified from a bacteriophage and put inside Pseudomonas aeruginosa was found to bypass the pathogen’s defense mechanisms to assemble into virions, which sliced through the bacterium’s cell to kill it.
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NewsPhages help to identify people at risk of developing TB
A novel approach to studying the progression of tuberculosis (TB) from infection to disease has identified and treated people at increased risk of developing the disease that current methods of testing would not.
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NewsPhages found that bring slumbering bacteria out of deep sleep and then kill them
Researchers questioning whether evolution might have produced bacteriophages that specialise in dormant bacteria and could be used to target them have now shown that such phages, though rare, do indeed exist.
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NewsPhages pay heavy price for environmental intel - but it’s worth it
Phages, the viruses that infect bacteria, will pay a high growth-rate cost to access environmental information that can help them choose which lifecycle to pursue, according to a study. Source: L. F. Lee; J. A. Boezi Bacteriophage gh-1 for Pseudomonas putida. Yigal Meir and colleagues at Ben-Gurion ...
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NewsGut bacteria combinations protect stem cell transplantation patients from dangerous immune reactions
Researchers have shown that graft versus host disease (GvHD) is less common when certain microbes are present in the gut. In the future, it may be possible to deliberately bring about this protective composition of the microbiome.