All Pseudomonas aeruginosa articles
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NewsA high-fat diet may impair response to infection
A new study in The Journal of Immunology reveals how a high-fat diet may impair the immune system’s ability to respond to infection by impacting the function of neutrophils, one of the first immune cells to respond to bacteria or viruses. The study demonstrated that male mice fed a high-fat ...
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NewsDamaged but not defeated: Bacteria use nano-spearguns to retaliate against attacks
Scientists used state-of-the-art microscopy technology to mimic a nano-speargun, the type VII secretion system, used as a bacterial pinpoint counterattack tactic in response to cell envelope damage against rival bacteria.
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NewsStudy uncovers the core principles of low-resistance antibiotics
Researchers have demonstrated that a dual-target approach, combining membrane disruption with an additional critical cellular pathway, significantly prevents the development of resistance in bacteria.
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NewsSuperbugs in our food: a new hope for tackling drug resistance
Researchers highlight the potential of quorum sensing inhibitors (QSIs) as a novel approach to tackle Pseudomonas aeruginosa. The study explores the mechanisms of action of various QSIs and potential applications in food safety and healthcare.
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NewsDangerous bacteria lurk in hospital sink drains, despite rigorous cleaning
Even in modern hospitals, drains can serve as reservoirs for known and novel pathogens, according to a new study.
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NewsDelicate nanoflower is deadly to bacteria
A carnation-like nanostructure could someday be used in bandages to promote wound healing. Researchers report that laboratory tests of their nanoflower-coated dressings demonstrate antibiotic, anti-inflammatory and biocompatible properties.
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NewsPapers outline 4 advances for inactivating infectious viruses and bacteria
Four papers provide insights into novel antiviral compounds and methods to inactivate infectious viral particles and bacteria.
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NewsResearchers identify genetic ‘fingerprint’ to predict drug resistance in bacteria
To avoid antibiotic overuse and allow precise bacterial infection treatment, particularly against bacteria with multidrug resistance, a diagnostic tool was developed that identifies the pattern of DNA repair deficiencies acting as the bacterial antibiotic resistance ‘fingerprint’.
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NewsCARB-X funds Rhode Island Hospital to assess feasibility of direct from blood detection of bacterial pneumonia
Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) will award Rhode Island Hospital at Brown University Health US$1M to demonstrate proof-of-concept of a polymerase chain reaction (PCR) approach informed by RNA sequencing to detect bacterial pneumonia directly from whole blood.
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NewsSophisticated early warning system: How bacteria respond to threats
Recent research has found that exogenous petidoglycan fragments of Vibrio cholerae and other multidrug-resistant pathogens are able to trigger 3D biofilm formation as an universial danger response.
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NewsOvercoming resistance: McMaster researchers find new utility for old antibiotics
In a recent study, researchers found that zinc plays a vital role in how some of the world’s most dangerous bacteria resist antibiotics.
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NewsDiverse phage populations coexist on single strains of gut bacteria
A new study shows that a single bacterial species, the host of a phage, can maintain a diverse community of competing phage species. Several phage species coexist stably on a population of a genetically uniform strain of E. coli.
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NewsHistones show promise against bacterial infections
Scientists have outlined that human histones have antimicrobial activity against different bacteria, including biofilms of Pseudomonas aeruginosa, one of the six most resistant bacteria in the world.
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NewsA lung pathogen’s dilemma: infect or resist antibiotics?
Research has uncovered how Pseudomonas aeruginosa manages the trade-off between colonizing and surviving during infection by switching between biofilm formation for antibiotic protection and a more mobile, “planktonic” state to spread and access nutrients.
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NewsStructural biology analysis of a Pseudomonas bacterial virus reveals a genome ejection motor
Bacterial viruses, known as phages, are the most abundant biological entities on the planet and are increasingly used as biomedicines to eradicate antibiotic-resistant pathogenic bacteria.
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NewsChemists pioneer metallodrug-antibiotic combination strategy to combat superbugs
A combination of different types of antibiotics with bismuth-based drugs, such as Pepto-Bismol, disrupts bacterial iron homeostasis, effectively restoring the bactericidal function of multiple antibiotics.
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News$7 Million grant to tackle lung infections through innovative probiotic treatment
The PROTECT project seeks to combat lung infections by assembling a community of beneficial lung microbes that can outcompete harmful pathogens.
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NewsNew discovery of how bacteria navigate their environment could change how we treat infection
Scientists have found that bacteria can directly measure differences in chemical concentration across the length of their cell bodies, contrary to decades of established scientific belief.
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NewsHydrometeorology and location affect hospitalizations for waterborne infectious diseases in the US
An analysis of 12 years of data collected from over 500 hospitals in 25 different states shows that weather, geographic location, and urban or rural location all appear to influence hospitalizations for waterborne infectious diseases.
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NewsPeptide cocktails could be key to fighting antibiotic resistance
A new study highlights the potential of random antimicrobial peptide mixtures to significantly reduce the risk of resistance evolution compared to single peptides, emphasizing the need for innovative solutions to outpace bacterial resistance and safeguard health.