All Research News articles – Page 43
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New immune mechanism revealed in the cellular trash
The enzyme, proteasomes known for its protein degradation and recycling system, has found to serve another useful purpose that provides promising alternatives for strengthening immune defenses against deadly diseases.
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Multi-dose vaccines administered in the same site boost immune response
New research suggests that receiving multiple doses of a vaccine in the same limb leads to faster antibody development, an important strategy for providing immunity as quickly as possible during a pandemic or disease outbreak.
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Gut bacterium IDed as key player in healing the colon
Researchers have identified Clostridium scindens, a bacterium that converts primary bile acids into 7α-dehydroxylated bile acids, as a key player in gut healing. Supplementing the gut with this bacterium could improve recovery from colonic injury.
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Intranasal herpes infection may produce neurobehavioral symptoms, study finds
A new study finds that herpes infection through the nose can lead to anxiety, motor impairment and cognitive issues. The research is the first to show that, by exploiting a cellular enzyme, the virus can produce behavioral symptoms.
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Circadian rhythms in tea plant microbiomes shed light on nutrient cycling
A groundbreaking study has uncovered a fascinating connection between the circadian rhythms of tea plants and the microbial communities in their rhizosphere, providing new insights into nutrient cycling.
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Study discovers tuberculosis genes necessary for airborne transmission
Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person’s lungs to another person’s during coughing, sneezing or talking, according to a study that offers new targets for tuberculosis therapies.
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Researchers pinpoint shared stress response network between long diverged algae and plants
A research team has compared algae and plants that span 600 million years of independent evolution and pinpointed a shared stress response network using advanced bioinformatic methods.
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Prevalence of neutralizing antibodies to AAV2 and AAV9 in individuals with Niemann-Pick disease
A new study shows that more than half of individuals with Niemann-Pick disease, type C1 (NPC1) who were tested lacked neutralizing antibodies against either adeno-associated virus (AAV) 2 or AAV9.
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Inhaled COVID vaccine study begins recruitment for phase-2 human trials
Researchers have started a phase-2 clinical trial on a next-generation, inhaled COVID-19 vaccine. Findings from the phase-1 trial indicate that the vaccine is more effective at inducing immune responses than traditional injected vaccines are.
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Genes combined with immune response to Epstein-Barr virus increase MS risk
In multiple sclerosis (MS), antibodies to the common Epstein-Barr virus can accidentally attack a protein in the brain and spinal cord. New research shows that the combination of certain viral antibodies and genetic risk factors can be linked to a greatly increased risk of MS.
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Research team publishes paradigm-challenging discovery in a Yellowstone thermophile
A graduating PhD student has made an interesting discovery about a common thermophilic bacteria dwelling in hots prings which is able to simultaneously respirate and metabolize via aerobic and anaerobic pathways.
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New discovery and grant to accelerate Strep A vaccine efforts
With a large sum of research funding and multinational contributions, the world’s only Strep A human challenge model will be used to resolve logistical issues and speed up the development of a successful Strep A vaccine.
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Novel enzyme found in gut bacteria could revolutionize prebiotic research
Researchers have discovered a new β-galactosidase enzyme in a human gut bacterium that breaks down and synthesizes previously unexplored glycans, which have prebiotic capabilities to improve gut health.
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Dermatophytes adaptation to the human host exemplified by Microsporum canis
Through comparative genomic analyses, researchers investigated the evolutionary mechanisms that underpin gene expansions to enable dermatophytes, such as Microsporum canis to transition from animal to human hosts.
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Great whale pee funnel carries nutrients thousands of miles, boosting phytoplanktons
A new study shows that whales carry huge quantities of nutrients horizontally, across whole ocean basins, from rich, cold waters where they feed to warm shores near the equator where they mate and give birth.
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Bacteria and minerals work together to detoxify arsenic in contaminated soils
New research shows that the interaction between arsenic-oxidizing bacteria and goethite, a common Fe mineral, significantly accelerates the conversion of arsenic from its highly toxic form, arsenite [As(III)], into the less harmful arsenate [As(V)].
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Early-life gut microbes may protect against diabetes, research in mice suggests
A research discovered that the colonization of a fungus called <i>Candida dubliniensis</i> in the early life gut microbiome of mice, is able to promote growth of pancreatic beta cells in the presence of macrophages to restore blood insulin level and improve metabolic functions, thus reducing risks of type 1 diabetes.
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Purified immunoglobulin F(ab′) 2 prevents lethal staphylococcal enterotoxin B intoxication in mice and rhesus monkeys
Purified F(ab′)2 fragments are an effective antidote to lethal SEB doses in mice and rhesus monkeys, and therefore might be a favorable candidate for treating patients with severe SEB intoxication, a new study suggests.
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Transcription factor PoMbp1 promotes the growth of Pleurotus ostreatus by regulating polysaccharide utilisation
A study investigating the growth and development of Pleurotus ostreatus has found that PoMbp1 contains an APSES domain and localizes to the nucleus, indicating it belongs to the fungal-specific APSES transcription factors family.
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Antimicrobial resistance in soil bacteria without the use of antibiotics
Overuse of antibiotics is currently the primary reason for the rise of antimicrobial resistance (AMR), but researchers have shown that AMR can be found in soil bacterial communities due to microbial interactions too, driven by a species of predatory bacteria.