All Research News articles – Page 44
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siRNA-AGO2 complex inhibits bacterial gene translation: a novel therapeutic strategy for superbug infection
Scientists have demonstrated that exosomes can serve as delivery vehicles to introduce AGO2-loaded siRNA into the cytoplasm of bacteria, and in turn down-regulated gene expression of the mRNA that shares sequence complementarity to the siRNA.
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Scietnists probe Rhytismataceae on twigs of Rhododendron
Following a study of fungal specimens collected from the twigs of Rhododendron species in China, three new genera were proposed and 21 species residing in 11 genera of Rhytismataceae were delimited, which include 18 new species and three new combinations.
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Effects of electroacupuncture combined with Chinese herbal medicine on gut microbiota and metabolomics in amyotrophic lateral sclerosis
Studies have highlighted a link between amyotrophic lateral sclerosis (ALS) and gut microbiota. A prospective study aimed to evaluate the effects of electroacupuncture combined with Chinese herbal medicine on gut microbiota and metabolomics in ALS patients.
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Novel insights into Candida glabrata in pregnant women’s reproductive tracts in Hainan
A study of Candida glabrata in pregnant women with vaginal discomfort at Haikou Maternal and Child Health Hospital found that 64.5% of the 594 yeast isolates (383 isolates) showed resistance (R) or intermediate (I) phenotypes to at least one of four commonly used antifungals.
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Ten new species of Leucoagaricus and Leucocoprinus from Beijing
A systematic survey of large fungi in urban green spaces in Beijing collected 88 specimens of Leucoagaricus and Leucocoprinus for morphological and multi-gene phylogenetic analysis. It found that 10 represent new species.
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Fewer than half of parents think they have accurate information about bird flu
Most parents say they don’t know if there have been cases of bird flu in their state, and less than half feel that they are able to find accurate and current information about it, according to a new national US poll.
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New study links sleep debt and night shifts to increased infection risk among nurses
A new study examining the effects of sleep patterns and shift work on the immune system has found that sleep debt and night shifts increase the risk of several common infections in nurses.
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Bacterial ‘jumping genes’ can target and control chromosome ends
Researchers have discovered a new mechanism that transposons, or “jumping genes” use to survive and propagate in bacteria with linear DNA, with applications in biotechnology and drug development.
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TB vaccine candidate provides ‘elite’ protection
A tuberculosis vaccine candidate under development shows complete protection and superior immune response in nonhuman primates compared to the existing BCG vaccine.
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A 'Trojan Horse' approach to develop new antimalarial drugs
Researchers have discovered a key process whereby malarial parasites take up a human blood cell enzyme, which could provide a new approach for antimalarial treatment.
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Method detects signs of life in ancient rocks - such as Mars samples
A new instrument was successfully developed to detect microbial lifeforms in ancient Earth rocks analogous to those found on Mars rocks, as a biohazard precaution measure when Mars rock samples are brought to Earth.
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Damaged but not defeated: Bacteria use nano-spearguns to retaliate against attacks
Scientists used state-of-the-art microscopy technology to mimic a nano-speargun, the type VII secretion system, used as a bacterial pinpoint counterattack tactic in response to cell envelope damage against rival bacteria.
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Research identifies key antibodies for development of broadly protective norovirus vaccine
A new study identifies powerful antibodies capable of neutralizing a wide range of norovirus strains. The finding could lead to the design of broadly effective norovirus vaccine, as well as the development of new therapeutic antibodies.
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Throat microbiome holds clues to older Australians’ health
A simple swab from the back of the throat, known as the oropharynx, may offer clues about health challenges faced by aged care residents.
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BAADesign enables the immune escaped etesevimab fully-armed against SARS-CoV-2 Omicron subvariants
BAADesign offers a powerful tool for reengineering monoclonal antibodies to combat emerging SARS-CoV-2 variants, providing a scalable solution for future pandemic preparedness, according to a new study.
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New antibodies show potential to defeat all SARS-CoV-2 variants
Researchers discovered that a paired combination of antibodies binding to the two domains of the SARS-CoV-2 viral particle showed promising results in elimination of all virus variants caused in the COVID-19 pandemic.
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Researchers see breakthrough in efficient biofuel production
Researchers have found ways to limit the toxicity to microbes generated by the biofuel butanol through fermentation of plant biomass, by manipulating the structure of microbe cell membrane at atomic level.
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Adaptation to extreme conditions: thermal water biofilm studies could help understand ancient ecosystems
Researchers have discovered unique bacterial communities in thermal waters that may help unravel the development of stromatolites, one of Earth’s oldest rock formations.
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Longer breastfeeding linked to blood-pressure lowering effects of certain infant gut bacteria
An observational study has found that infants who had more diverse bacteria in their gut had lower childhood blood pressure, and this protective association was stronger if they were breastfed for at least six months.
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White blood cells use brute force to dislodge bacteria
A $2.3 million grant from the National Institutes of Health (NIH).will support research into blood platelets and macrophages; how integrin tension influences cell function; and how this force affects platelet behavior.