All Research News articles – Page 39
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Scientists uncover new mechanism in bacterial DNA enzyme opening pathways for antibiotic development
Researchers have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent in humans, plays a crucial role in supercoiling DNA, a necessary process for bacterial survival.
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Natural saclipins in cyanobacteria offer hope of combating skin aging
A new study reveals that saclipins, derived from edible cyanobacterium, enhance collagen and support skin whitening and anti-aging.
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Probiotic may counteract fire-retardant chemical damage
A mouse study reports that probiotic supplementation can reduce the negative impacts of polybrominated diphenyl ethers, or PBDEs - fire-retardant chemicals - on neurodevelopment, behavior, and metabolism.
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Parkinson’s drug changes the gut microbiome for the worse due to iron deficiency
Scientists have revealed that the widely prescribed Parkinson’s disease drug entacapone significantly disrupts the human gut microbiome by inducing iron deficiency.
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Finding a preventative solution to a billion-dollar poultry problem
A poultry science researcher is evaluating a new possible solution to losses due to necrotic enteritis, using a novel vaccine combined with a bile acid regimen.
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Scientists implicate a novel cellular protein in hepatitis A infection
Viruses have thrived in humans for tens of thousands of years, evolving to take advantage of the machinery of cells to replicate and survive inside us. Some can slip past our defenses and invade without even causing symptoms. Source: Shirasaki et al. (2024) (Left) Liver cells infected with ...
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Soil ecosystem more resilient when land managed sustainably
Compared to intensive land use, sustainable land use allows better control of underground herbivores and soil microbes, a new study shows. The soil ecosystem is thus more resilient and better protected from disturbance under sustainable management.
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Artificial intelligence can be used to treat infections more accurately
New research has shown that using artificial intelligence (AI) can improve how we treat urinary tract infections (UTIs), and help to address antimicrobial resistance (AMR).
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Genomic surveillance studies reveal circulation of multidrug-resistant Enterobacterales in Europe
Two studies indicate warning signs about spread of bacteria resistant to the same group of antibiotics (carbapenems) in both healthcare and community settings across Europe.
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Study probes effects of livestock-keeping on transmission of mosquito-borne diseases
A new study examines the effects of livestock husbandry on mosquito population density and the spread of mosquito-borne diseases (MBDs), to raise public awareness of how to protect against MBDs.
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Scientists develop breakthrough culture system to unlock secrets of skin microbiome
The co-culture system for skin microbiome can help understand interactions between bacterial species, aiding the development of specialized skin treatments.
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How protective antibodies get in malaria’s way
Researcher’s structural insights help reveal weak spot in parasite’s plan of attack which could help guide vaccine design.
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Gut feelings: Social connections change our microbiomes
Friends tend to share common interests, tastes, lifestyles, and other traits, but a new Yale-led study demonstrates that similarities among buddies can also include the makeup of the microbes lining their guts. The study, published Nov. 20 in the journal Nature, examined the relationship between the structure ...
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The mystery of the secretly sexual lichens
Researchers were shocked to find that a type of lichen called Lepraria, long assumed to be asexual, still has the genes that govern sexual reproduction.
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Study uncovers key heart responses to viral infection
Researchers at the University of Virginia have made a significant discovery that could change how doctors treat viral infections of the heart. Source: UVA Engineering Kevin Janes, University of Virginia John Marshall Money Professor, Department of Biomedical Engineering and Department of Biochemistry & Molecular Genetics. The ...
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Researchers catalog the microbiome of US rivers
River microbes found near wastewater treatment plants expressed high levels of antibiotic resistance genes, reveals a study of the presence and function of microbes in rivers covering 90% of the watersheds in the continental U.S.
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Human antibodies could prevent the malaria parasite from causing life-threatening infections
Malaria, particularly in its severe forms, remains a global health and economic burden. It causes the deaths of more than 600,000 people every year – most of them African children under five. In a new study, published in the journal Nature, researchers from EMBL Barcelona, the University of Texas, the ...
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Enzyme produced by pathogenic fungus helps evade immune system and facilitates infection
Researchers found 62 proteins specific to spores of Aspergillus fumigatus, a fungal species that causes lung disease. The study showed that at least one of these proteins inhibits human human defense mechanisms.
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Cigarette smoke alters microbiota and aggravates flu severity
New research has shown that cigarette smoke can induce disordered oropharyngeal microbiota that aggravates the severity of influenza A virus infection.
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Innovative antibiotic shows promise for drug-resistant bacteria
Researchers have demonstrated a potential antibacterial treatment from a modified darobactin, reporting proof-of-concept animal trials on infections caused by bacteria, including E. coli, that are known to develop drug resistance.