All Research News articles – Page 39
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Newer hepatitis B vaccine shows promise as booster for health care workers
A new study compares the effectiveness of Heplisav-B, a new hepatitis vaccine, vs. standard hepatitis B vaccines as a booster in previously vaccinated individuals.
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Evaluating DNA impurities in recombinant adeno-associated virus
A new study indicates that DNA impurities derived from plasmid and host cell DNA are encapsulated into recombinant adeno-associated virus (rAAV) capsids as single-stranded DNA.
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Biogenic construction: The new era of civil engineering
Inspired by the concept of harmonious coexistence between humans and nature, a new concept, biogenic construction, for civil engineering is proposed in a new paper.
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New study reveals a safer alternative for long-term hepatitis B treatment
Researchers have studied the effects of switching from long-term tenofovir disoproxil fumarate to the antiviral besifovir dipivoxil maleatein (BSV) in patients with chronic hepatitis B. Switching to BSV may improve patient kidney and bone health.
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Rapid and accurate diagnosis of urinary tract infections using targeted next-generation sequencing
A study shows that tNGS demonstrates advantages in rapid and accurate UTI diagnosis, particularly in detecting polymicrobial infections and analyzing antibiotic resistance genes. It shows promise as an effective complementary tool for UTI diagnostics.
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Breaking antibiotic-resistant bacteria’s protective shields opens door for immune system response
Researchers have made progress in uncovering how Streptococcus pneumoniae constructs its capsule, which serves as a protective shield. This capsule is a primary target for vaccine development.
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Study evaluates airborne transmission risk of mpox compared to COVID-19 and smallpox
Scientists have found that the inhaled infectious dose of mpox is at least 100 times lower than that of SARS-CoV-2 and smallpox, making efficient respiratory aerosol transmission highly unlikely in its current form - but future viral evolution could alter this dynamic.
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Scientists ID natural products targeting SARS-CoV-2 - including caffeine
Researchers used computational methods to identify potential inhibitors of SARS-CoV-2 spike proteins, revealing promising natural compounds for guiding antiviral drug development, including caffeine.
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New study sheds light on how bacteria ‘vaccinate’ themselves with genetic material from dormant viruses
Scientists have gained understanding on how bacteria defend themselves from phages, through gaining “memories” from predecessor dormant phages. The study will inform new phage therapies for bacterial infections that confer resistance to antibiotics.
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Movie reveals DNA unzipping mechanism with implications for viral and cancer treatments
A detailed unwinding mechanism of the double-stranded DNA has been uncovered for the first time using cutting-edge technology, revealing how cells begin the crucial process of copying their genetic material.
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Green recipe: Engineered yeast boosts D-lactic acid production
An optimal combination of genetic “recipe” in a yeast strain achieves high yields of D-lactic acid production from methanol, advancing eco-friendly and sustainable biomanufacturing.
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Bartonella and babesia found in brain tissue of child with seizures
In a new case study, researchers have found Bartonella henselae, Babesia odocoilei and Babesia divergens-like MO-1 DNA in brain tissue samples from a young child with seizures and suspected Rasmussen’s encephalitis.
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Origin of life: How microbes laid the foundation for complex cells
Researchers examining links between Asgard archaea and eukaryotes have shown that Asgard tubulins form similar microtubules, albeit smaller than those in their eukaryotic relatives. Unlike actin, these tubulin proteins appear in very few species of Asgard archaea.
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Antibody-based therapy is several steps closer to treat lethal mucormycosis
A new paper discusses the use of monoclonal antibodies to target a key fungal cell surface protein, CotH, which enables the Mucorales fungus to invade human cells and cause mucormycosis, which has high mortality rates in people with weakened immune systems.
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A high-fat diet may impair response to infection
A new study in The Journal of Immunology reveals how a high-fat diet may impair the immune system’s ability to respond to infection by impacting the function of neutrophils, one of the first immune cells to respond to bacteria or viruses. The study demonstrated that male mice fed a high-fat ...
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New model predicts how bacteria navigate obstacles to spread
A scientist has developed the first analytical model for predicting how bacteria spread in environments filled with obstacles. This model will help inform strategies for curbing bacterial infections or for designing better drug delivery.
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Researchers test new, more reliable method to detect chagas disease
Researchers have successfully tested a faster, more sensitive and reliable way to diagnose Chagas disease, a debilitating parasitic illness that affects approximately 6 million people worldwide.
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From pollution to polymer: Methane-munching microbe brews biodegradable plastic at high speed
Scientists have tapped into a methane-consuming bacterium, Methylocystis suflitae, to produce biodegradable plastics called polyhydroxyalkanoates (PHAs), offering a dual win for climate and sustainability.
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Nature’s warriors: How rice plants detect and defend against viral invaders
A groundbreaking study uncovers a molecular mechanism by which rice cells perceive viral infections and initiate antiviral response, which significantly contributes to understanding of virus-host interactions for further disease resistance breeding.
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Gatekeeping barriers manage communications between plants and bacteria
For over a century, the Casparian strip has been known as the root’s doorman, controlling what enters the plant. But a new study reveals it has a second job: regulating the delicate metabolic trade between plants and bacteria.