All SARS-CoV-2 articles – Page 7
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Oral nucleoside antiviral is progressing toward future pandemic preparedness
Oral obeldesivir has been shown to reduce disease severity in mice infected with one of several different coronaviruses, including SARS-CoV-2 (which causes COVID-19), SARS-CoV and MERS-CoV.
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Pathway into cell influences the outcome of SARS-CoV-2 infection
The protein TMPRSS2 acts as a helper to bring the virus into the cell via the receptor ACE2. This TMPRSS2-mediated uptake significantly alters the immune response of the host cells and drives the evolution of the virus, a new study shows.
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Scientists develop new nanoscale way to see viruses in action
A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, scientists report.
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Statisticians call for rigour and transparency in the evaluation of diagnostic tests
Recommendations designed to reframe the evaluation of in vitro diagnostic tests have been published - intended to help prevent future scenarios in which IVDs are marketed widely, but later attract serious concerns about the standards applied to their evaluation.
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Knowledge is a factor in closing black-white COVID-19 vaccination gap
Early in the Covid-19 pandemic, Black Americans were more hesitant to take the Covid-19 vaccine than were White Americans. As the pandemic went on, however, the disparity in vaccination rates between Black and White adults declined. Source: Baltimore County Government People queueing to be vaccinated, 23 December 2020 ...
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New electrostatic sampler boosts indoor virus detection speed
Researchers have developed a groundbreaking electrostatic air sampler that enhances the rapid monitoring of airborne influenza and coronavirus.
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Study shows N95 masks near-perfect at blocking escape of airborne COVID-19
In a head-to-head comparison of masks worn by people with active COVID-19, the inexpensive ‘duckbill’ N95 came out on top, stopping 98% of COVID-19 particles in the breath of infected people from escaping into the air.
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Effectiveness of updated COVID-19 vaccines wanes moderately over time, is lower against currently circulating variants
New research shows boosters targeting omicron subvariants of SARS-CoV-2 are still providing reasonably durable protection against infection, hospitalization and death from COVID-19, but are less protective against the JN.1 strain.
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Researchers take step toward development of universal COVID-19 antibodies
Scientists have developed a promising new human monoclonal antibody that appears a step closer to a universal antibody cocktail that works against all strains of SARS-CoV-2.
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Risk of death from COVID-19 lessens, but infection still can cause issues 3 years later
A new study also shows that patients hospitalized within 30 days after infection face a 29% higher death risk in the third year compared with those not infected.
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Scientists probe missing microbes in infants and children in the COVID-19 pandemic
Researchers conducted a comparative analysis of the gut microbiome of 1,126 children and infants during the COVID-19 pandemic in the Beijing area, revealing the variation of their gut microbiome.
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Century-old vaccine protects type 1 diabetics from infectious diseases
Research shows that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.
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How vaccine messaging is framed makes a difference, new research reveals
A one-size-fits-all approach to communicating the benefits of vaccines isn’t effective. Message framing plays a crucial role depending on the mindset, so it requires communicating in different ways for different people, a new study says.
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Long-term protection from SARS-CoV-2 variants in mice by a Phase II clinically evaluated original mRNA vaccine booster
A new study discusses the development of an mRNA vaccine (LVRNA009) that encoded the S protein of the Wuhan-Hu-1 strain and evaluated the long-term protection potential against SARS-CoV-2 variants.
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Wearing face masks did not reduce risk of COVID infection after first Omicron wave, research shows
A study has found that wearing face masks did not lower the risk of Covid infection following the initial surge of the Omicron variant. Overseas travel was not associated with increased risk prior to February 2022, but then became a significant risk.
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Virus that causes COVID-19 can penetrate blood-retinal-barrier and could damage vision
Using a humanized mouse model, researchers have discovered the virus that causes COVID-19 can breach the protective blood-retinal barrier with potential long-term consequences in the eye.
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Biophysicist F. William Studier awarded Merkin prize in biomedical technology
F. William Studier, a senior biophysicist emeritus at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory, has won the 2024 Richard N. Merkin Prize in Biomedical Technology for his development in the 1980s of an efficient, scalable method of producing RNA and proteins in the laboratory. Source: ...
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SARS-CoV-2 and type 1 diabetes in children: new study aims to explore the relationship
A new study will investigate whether vaccination against SARS-CoV-2 in the first year of life can protect children who have an increased genetic risk for type 1 diabetes from developing the condition.
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A third Covid vaccine dose improves defence for some clinically extremely vulnerable patients
A major clinical trial has found that an additional COVID 19 vaccine dose led to the majority of clinically extremely vulnerable people mounting defensive antibodies against Covid-19.
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An adjuvant made in yeast could lower vaccine cost and boost availability
Scientists have wielded the power of synthetic biology to produce the active ingredient of soap bark, a molecule called QS-21, in yeast - a more environmentally friendly way to produce a key ingredient of vaccines.