All SARS-CoV-2 articles – Page 6
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Antibody-based therapy is several steps closer to treat lethal mucormycosis
A new paper discusses the use of monoclonal antibodies to target a key fungal cell surface protein, CotH, which enables the Mucorales fungus to invade human cells and cause mucormycosis, which has high mortality rates in people with weakened immune systems.
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McMaster leads Canada’s first-ever guidelines for Post COVID-19 Condition
A team of experts from McMaster University has led the creation of Canada’s first-ever comprehensive guidelines for diagnosing, managing, preventing, and treating post COVID-19 condition (PCC), more commonly known as long COVID.
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COVID-19 pandemic worsened mother and infant birth outcomes
Mothers who became pregnant after the start of the pandemic, those who experienced moderate-to-severe infections during pregnancy, and those who had infections during the third trimester were more likely to have adverse outcomes.
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CeSPIACE: A broad-spectrum peptide inhibitor against variable SARS-CoV-2 spikes
CeSPIACE, a small remodified peptide, is able to block the binding of ACE2 receptor and the spike protein on SARS-CoV-2 and its variants. Hence, the cheap and simple peptide could treat COVID-19 infection and prevent reinfection after exposure of the virus.
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Symptoms of long-COVID can last up to two years after infection with COVID-19
According to a study of the COVICAT cohort, almost one in four people infected with SARS-CoV-2 suffered from long-COVID. In more than half of them the symptoms persisted for two years.
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Cause of post-COVID inflammatory shock in children identified
MIS-C is a serious inflammatory shock that affects children and can occur several weeks after a COVID infection. Researchers have found that reactivation of a pre-existing, dormant infection with the Epstein-Barr virus triggers an excessive inflammatory response.
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Multi-dose vaccines administered in the same site boost immune response
New research suggests that receiving multiple doses of a vaccine in the same limb leads to faster antibody development, an important strategy for providing immunity as quickly as possible during a pandemic or disease outbreak.
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Inhaled COVID vaccine study begins recruitment for phase-2 human trials
Researchers have started a phase-2 clinical trial on a next-generation, inhaled COVID-19 vaccine. Findings from the phase-1 trial indicate that the vaccine is more effective at inducing immune responses than traditional injected vaccines are.
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BAADesign enables the immune escaped etesevimab fully-armed against SARS-CoV-2 Omicron subvariants
BAADesign offers a powerful tool for reengineering monoclonal antibodies to combat emerging SARS-CoV-2 variants, providing a scalable solution for future pandemic preparedness, according to a new study.
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Scientist who deployed glowing stars to detect disease named fellow of the Royal Society of Chemistry
The man who turned the science of glow-in-the-dark stars into ways to detect disease, Professor Richard Willson, has been elected as a fellow of the Royal Society of Chemistry.
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New COVID-flu vaccine platform could provide broad, lasting protection
Researchers have developed a new vaccine platform that could provide more robust, longer-lasting protection from both COVID-19 and influenza, and broader immunity to different flu strains.
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Lung abnormalities seen in children and teens with long COVID
An advanced type of MRI uncovers significant lung abnormalities in children and adolescents with long COVID, according to a new study. PREFUL MRI doesn’t require the use of radiation or intravenous contrast agents and can be done while the patient breathes freely.
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Paxlovid’s impact on hospitalization and death in COVID-vaccinated older adults far weaker than previously thought
A new study overturns the assumption that Paxlovid’s effectiveness in reducing COVID-19 hospitalizations and deaths in unvaccinated adults also applies to vaccinated adults.
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Machine learning framework can decipher immune system’s record of past infections
A novel machine learning framework can decipher an individual’s immune system’s record of past infections and diseases, providing a powerful tool with the potential for diagnosing autoimmune disorders, viral infections, and vaccine responses with precision.
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New modeling approach could help design antivirals for shape-shifting viruses
New research utilizes an innovative computational modeling approach to capture the complex and diverse shapes that viral proteins can adopt.
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Bat genome signposts new potential pathway to fight viruses with genomic characterization
A promising discovery has been made from a study that deciphers how bats are more resistant to viral infections than human using genome annotations of transposable elements in bats to pave a way for adapting the bats’ immunity against future viral outbreaks.
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Nasal COVID-19 vaccine to enter US clinical trials
A nasal vaccine for COVID-19 is poised to enter a phase 1 clinical trial in the U.S. after an investigational new drug application from Ocugen, Inc. was approved by the Food and Drug Administration (FDA).
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Virus that causes COVID-19 increases risk of cardiac events
A new study found severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was associated with the rapid growth of plaque in the coronary arteries and an increased risk of cardiovascular events.
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New method offers faster response to new virus variants
Researchers present a promising approach for swift identification of mutations that are crucial for the immune escape that enables the rapid adaptation of vaccines to new virus variants. It is based on a previously established method called mutational scanning.
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Study investigates ozonated water’s effectiveness against SARS-CoV-2 in saliva
A research group examined the human salivary organic components, amylase, mucin, and urea, and ozonated water’s effect on SARS-CoV-2 in the presence of these components.