All SARS-CoV-2 articles – Page 2
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News
Researchers uncover the antiviral potential of defensins
Scientists have discovered that certain defensins - tiny proteins with powerful antimicrobial potential - could block the virus that causes COVID-19 (SARS-CoV-2) from entering human cells.
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Beyond health: The political effects of infectious disease outbreaks
A new study gives empirical evidence that individuals who experienced an infectious disease outbreak show significantly less trust in the political establishment.
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Long Covid lessons: New cell therapy boosts immune recovery in cats with severe coronavirus
Feline infectious peritonitis is a serious and historically fatal disease in cats caused by a coronavirus. Scientists have found that mesenchymal stromal cells, or MSC therapy, in combination with antiviral drugs, helped cats’ immune systems recover and reduced systemic inflammation.
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Novel open-source diagnostic tool offers affordable, reliable pathogen detection for resource-limited settings
Researchers have developed an open-source reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay that is lyophilized for heat stability and uses non-proprietary components, making it an affordable tool for pathogen detection in diverse settings.
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Tiny chip speeds up antibody mapping for faster vaccine design
By analyzing just a drop of blood, this microchip gives researchers quicker-than-ever insight into how a person’s antibodies are interacting with a virus or other pathogen.
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From COVID to cancer, new at-home ‘coffee-ring’ test spots disease with startling accuracy
A new, low-cost biosensing technology could make rapid at-home tests up to 100 times more sensitive to viruses like COVID-19. The diagnostic could expand rapid screening to other life-threatening conditions like prostate cancer and sepsis as well.
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Comprehensive review sheds light on rare blood clotting syndrome linked to COVID-19 vaccines
A new analysis has provided critical insights into the rare but serious condition known as vaccine-induced immune thrombotic thrombocytopenia (VITT). The findings confirm a higher risk of arterial and venous thrombosis after COVID-19 infection compared to vaccination.
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Low dose of hydroxychloroquine is associated with reduced COVID-19 mortality: study
A new study provides observational evidence that low-dose hydroxychloroquine is associated with reduced COVID-19 mortality in hospitalized patients, particularly those with severe illness, when administered within the first week of symptoms.
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Scientists find flawed data in recent study relevant to coronavirus antiviral development
A new study shows why scientists still don’t know how the NiRAN domain works. The findings could have sweeping implications for drug developers already working to design antivirals based on flawed assumptions, and underscore the importance of rigorous validation.
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Adults who have survived childhood cancer are at increased risk of severe COVID-19
People who have survived cancer as children are at higher risk of developing severe COVID-19, even decades after their diagnosis. This is shown by a new study from Karolinska Institutet published in the journal The Lancet Regional Health – Europe.
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Research suppresses coronavirus by targeting Mac1
A new study details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the “macrodomain,” found in all coronaviruses such as SARS-CoV-2 and MERS-CoV.
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Airborne fungal spores may help predict COVID-19 & flu surges
Monitoring fungal spores in the outdoor air can predict surges in flu and COVID-19 infections, especially during the fall, according to a new study
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Immune ‘dysregulation’ present prior to infection predicts severe responses
A study shows that a common gene signature of immune health or dysfunction predicts severe outcomes from infection, and is present in people with known risk factors such as being a smoker or having a high body mass index, even before they encounter a pathogen.
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Features
Genome sleuths: using DNA to trace the evolution of animal-to-human pathogens
Zoonotic spillovers have become a significant focus of global health, with outbreaks like SARS and COVID-19 underscoring how quickly these events can escalate into worldwide crises. Genomics is crucial in tracing the origins and predicting the emergence of zoonotic threats.
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Broad-spectrum coronavirus drug developed through AI-enabled dynamic modeling
Multidisciplinary AI- and physics-driven modeling of the viral fusion process enables discovery of an orally available drug inhibiting infection with multiple coronaviruses.
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Researchers discover protein necessary for SARS-CoV-2 to evade the body’s defenses
Researchers have identified a protein that plays a key role in helping SARS-CoV-2 hide from the body’s defenses by suppressing the production of viral double-stranded (dsRNA), leading to increased viral replication while limiting the body’s immune response.
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Researchers identify new llama-derived antibodies against current and future coronaviruses
Scientists have discovered a unique class of small antibodies that are strongly protective against a wide range of SARS coronaviruses, including SARS-CoV-1 and numerous early and recent SARS-CoV-2 variants.
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Vaccinated patients hospitalized with COVID-linked acute kidney injury less likely to need dialysis after discharge
Vaccinated patients hospitalized with COVID-19 who developed acute kidney injury had better outcomes than unvaccinated patients with the same condition, new research suggests. The study found vaccinated patients were less likely to stay on dialysis after discharge, and more likely to survive, than unvaccinated patients.
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Geographic bias in virus naming: Lessons from coronavirus show it’s better to act early
A new study highlights the need to avoid geographically-based naming right from the outset of a pandemic. It analyzes the impact of the WHO’s introduction of the Covid nomenclature based on Greek letters - Alpha, Beta, Delta, etc.
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Study indicates that severe forms of COVID-19 infection in children may increase cardiovascular disease risks
Scientists analysed blood samples from 147 children across different COVID-19 conditions and identified significant metabolic disruptions beyond the acute viral infection phase. These alterations affect how the body processes fats (triglycerides and cholesterol) critical to healthy heart structure.