All viral reservoirs articles
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NewsNext-generation ‘molecular scissors’ may offer hope for chronic hepatitis B sufferers
Researchers have developed engineered precision ’molecular scissors’ that can permanently disable the genetic blueprint of the hepatitis B virus (HBV). The approach directly targets covalently closed circular DNA (cccDNA), the stubborn viral reservoir.
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NewsHIV discovery could open door to long-sought cure
Scientists have uncovered a key reason why HIV remains so difficult to cure: Their research shows that small changes in the virus affect how quickly or slowly it replicates, and how easily or stubbornly it can reawaken from hiding.
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NewsScientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
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NewsCovid persistence in lungs linked to failure of innate immunity
A new study shows that SARS-CoV-2 is found in the lungs of certain individuals for up to 18 months after infection, and that its persistence appears to be linked to a failure of innate immunity (the first line of defense against pathogens).