All West China Hospital of Stomatology articles
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NewsSAA1+ epithelial cells emerge as inflammatory ringleaders in periodontitis
Periodontitis is driven not only by bacteria but by how the gingival epithelium responds to them. This study maps that response at spatial and single-cell resolution, showing that a distinct serum amyloid A1 (SAA1)-high inflammatory epithelial subpopulation (SAA1+Epi) sits at the junctional epithelium, where subgingival plaque meets host tissue. ...