All Young Innovators articles
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Gut bacteria can reveal colorectal cancer
Researchers identified all human gut bacteria to a level of detail that uncovers the physiological importance of the different microbial subgroups. This inventory was then used to detect the presence of colorectal cancer according to the bacteria present in simple stool samples.
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‘Controlled evolution’ dramatically boosts pDNA production for biomedical manufacturing
Researchers have controlled the evolution of E. coli bacteria in the lab in order to dramatically increase the amount of plasmid DNA (pDNA) these modified bacteria produce. pDNA is an essential – and expensive – ingredient in many gene therapies.
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Nanoparticles that self-assemble at room temperature could transform vaccine delivery
Researchers have engineered polymer-based nanoparticles that form with a simple temperature shift—no harsh chemicals, no specialized equipment, and no processing needed. They can self-assemble at room temperature and deliver RNA to living cells.
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Anti-neuroinflammatory natural products from isopod-related fungus now accessible via chemical synthesis
Herpotrichone is valued for its ability to suppress inflammation in the brain and protect nerve cells, but could only be obtained in minute quantities from fungi that are symbiotic with isopods. Researchers have succeeded in chemically synthesizing this rare natural product.
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New imaging approach transforms study of bacterial biofilms
Scientists have reimagined the capabilities of atomic force microscopy, transforming it into a tool that captures large-scale biological architecture. This advance offers an unprecedented view of biofilm organization.
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Two new solutions for coral protection: a conductive biopaste and a natural healing patch
A research group in Italy has developed two new coral protection technologies for healing and restoring coral reefs: a biopaste and a natural patch, both successfully tested on real corals.
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How AI can enhance early detection of emerging viruses: study
Coupling wastewater surveillance and a newly developed AI algorithm can help public health organizations more quickly predict potential outbreaks, a new study suggests.
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Researchers develop process to turn food waste into biodegradable plastic
Researchers have developed a process to turn food waste into biodegradable plastic. Their new study offers fundamental findings for any company interested in scaling up the process.
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Bacterial genomes hold clues for creating personalized probiotics
A new study demonstrates the ability to predict the nutritional adaptations of Bifidobacterium strains by analyzing the distribution of hundreds of metabolic genes in thousands of Bifidobacterium genomes.
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Researchers engineer a microbial platform for efficient lutein production
The application of systems metabolic engineering strategies, and construction of an electron channeling system, has enabled the first gram-per-liter scale production of lutein from Corynebacterium glutamicum, providing a viable alternative to plant-derived lutein production.
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Novel open-source diagnostic tool offers affordable, reliable pathogen detection for resource-limited settings
Researchers have developed an open-source reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay that is lyophilized for heat stability and uses non-proprietary components, making it an affordable tool for pathogen detection in diverse settings.
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Tiny chip speeds up antibody mapping for faster vaccine design
By analyzing just a drop of blood, this microchip gives researchers quicker-than-ever insight into how a person’s antibodies are interacting with a virus or other pathogen.
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Researchers develop superstrong, eco-friendly materials from bacteria
Scientists have developed a scalable approach to engineer bacterial cellulose into high-strength, multifunctional materials. Their biosynthesis technique aligns bacterial cellulose fibers in real-time, resulting in robust biopolymer sheets with exceptional mechanical properties.
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Engineers develop electrochemical sensors for cheap, disposable diagnostics
Electrodes coated with DNA could enable inexpensive tests with a long shelf-life, which could detect many diseases and be deployed in the doctor’s office or at home.
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Machine learning method helps bring diagnostic testing out of the lab
A new point-of-care biosensing method, dubbed LOCA-PRAM, improves the accessibility of biomarker detection by eliminating the need for technical experts to perform the image analysis.
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Scientists develop a treatment platform to disable the ‘biofilm’ shield of superbugs
Researchers have developed a platform that utilizes microbubbles to deliver gene-targeted nanoparticles capable of breaking down MRSA biofilms, offering an innovative solution for treating infections resistant to conventional antibiotics.
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Nature’s toolkit: Scientists breed mushrooms to build versatile natural substitutes for commonly used materials
Scientists have shown that natural genetic variations in a common species of mushroom can be used to create new strains capable of making customized, biodegradable replacements for fabric, plastic, packaging and other environmentally harmful materials.
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Researchers develop dissolvable battery using probiotics
A new paper shows the potential of using probiotics — live microorganisms that offer health benefits when ingested but are otherwise harmless.
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Researchers pioneer nanoparticle approach to fight poultry disease
Researchers have demonstrated that a novel protein-based nanoparticle can make mRNA vaccines more effective to tackle a troublesome pathogen in chickens.
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Nanoparticle smart spray helps crops block infection before it starts
As climate change fuels the spread of plant diseases worldwide, a new nanoparticle smart spray could help crops defend themselves by blocking harmful bacteria from entering through tiny pores in their leaves.