All Antimicrobial Resistance articles – Page 21
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NewsResearchers discover source of deadly fungal infections in bone marrow transplant patients
Scientists have found that heteroresistance is the reason a small number of transplant patients developed bloodstream infections, despite receiving prophylaxis with the antifungal drug micafungin.
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NewsSuper cally molecules take down tuberculosis
Researchers have identified and synthesised a group of molecules that can act against the cause of tuberculosis in a new way. The callyaerins act against TB by employing a fundamentally different mechanism compared to antibiotic agents used to date.
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NewsNew compound found to be effective against flesh-eating bacteria
Researchers have developed a novel compound that effectively clears bacterial infections in mice, including those that can result in rare but potentially fatal ‘flesh-eating’ illnesses, and could be the first of an entirely new class of antibiotics.
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NewsHuman clinical study launched using phage lysin to eliminate staph in the nasal microbiome
A “first-in-human” study with the novel drug candidate HY-133 began on 10 July with the recruitment of clinically healthy volunteers who tested positive for Staphylococcus aureus colonisation of the nose.
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NewsAI opens door to safe, effective new antibiotics to combat resistant bacteria
A large language model—an AI tool like the one that powers ChatGPT—has been used to engineer a version of a bacteria-killing drug that was previously toxic in humans.
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NewsDerivative of the long pepper battles bacterial biofilms
Scientists investigating the long pepper - known in traditional medicine for its treatment of a variety of illnesses - have created a derivative that disrupts bacterial chemical communication.
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NewsDual action antibiotic could make bacterial resistance nearly impossible
A new antibiotic that works by disrupting two different cellular targets would make it 100 million times more difficult for bacteria to evolve resistance, according to new research
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NewsNew agent effective against drug-resistant malaria parasites
Scientists have developed a promising new antimalarial agent, DIF-1(+3), which is a derivative of Dictyostelium differentiation-inducing factor-1 (DIF-1).
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NewsNew UK research networks will tackle antimicrobial resistance
Eight new UK networks, combining different research specialisms, will work together to tackle one of humanity’s biggest threats, antimicrobial resistance (AMR).
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NewsAMAST Network launches to battle AMR in the agrifood system
AMAST – the AMR in Agrifood Systems Transdisciplinary Network, has been created to harness perspectives from across agrifood stakeholders and prepare new ways to tackle these challenges.
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NewsPeptide cocktails could be key to fighting antibiotic resistance
A new study highlights the potential of random antimicrobial peptide mixtures to significantly reduce the risk of resistance evolution compared to single peptides, emphasizing the need for innovative solutions to outpace bacterial resistance and safeguard health.
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NewsScientists identify possible new transmission factor in hospital-acquired Klebsiella infections
The dangerous multidrug resistant (MDR) pathogen, Klebsiella, thrives under nutrient-deprived polymicrobial community conditions found in hospital environments, a new study reveals.
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NewsSurgical Infection Society issues new guidelines on the management of intra-abdominal infection
The Surgical Infection Society (SIS) has presented new evidence-based guidelines for the management of intra-abdominal infection (IAI) in the peer-reviewed journal Surgical Infections. “These guidelines are critical in the ongoing work by the Surgical Infection Society to decrease the number of deaths from the most common ...
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NewsRising antimicrobial resistance in some Salmonella serovars isolated from retail chicken meat
Salmonella infections are a major public health issue in the United States, causing over 1.3 million illnesses annually. These infections are a leading cause of foodborne illness, often traced back to raw or undercooked poultry meat and eggs. Source: National Institute of Allergy and Infectious Diseases Scanning electron ...
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NewsNew ECDC Director Pamela Rendi-Wagner emphasises importance of restoring public trust in science after pandemic
Incoming ECDC Director Dr Pamela Rendi Wagner has outlined her vision for the agency, highlighting the challenges to public health after the COVID-19 pandemic, including war in Europe, climate change, and increasing social inequalities.
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NewsUrgent action needed to combat rising antimalarial resistance in Africa
Urgent action is needed to prevent a surge in malaria-related sickness and death in eastern Africa, scientists say.
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NewsHarnessing big data helps scientists hone in on new antimicrobials
Scientists have detailed a new method of identifying antimicrobial enzymes from large datasets of bacterial proteins, which could provide a solution to antibiotic resistance.
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NewsScientists pioneer comprehensive derivative synthesis method for developing new antimicrobial drugs
A method to screen a wide variety of drug candidates without laborious purification steps could advance the fight against drug-resistant bacteria.
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NewsE. coli variant may cause antimicrobial resistance in dogs and humans
Researchers studying antimicrobial-resistant E. coli – the leading cause of human death due to antimicrobial resistance worldwide – have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.
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NewsDischarge of untreated hospital effluent is a key driver of multidrug resistance, study finds
A new study has highlighted the discharge of untreated hospital effluent to the environment as a major driver of multidrug resistance among the microbial community.