All Antimicrobial Resistance articles – Page 46
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NewsMolecular insights may inform new treatments for drug-resistant TB
Researchers have used state-of-the-art imaging to examine two new compounds that target ATP synthase, potentially stopping TB bacteria from producing the energy they need to survive.
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OpinionCould deep sea mining destroy the treasure trove of biomedical compounds yet to be found?
The idea of DSM has been proposed, backed by countries such as the UK, France, Germany, Spain, USA and China in the search for metals such as iron, manganese, copper, zinc, lead, nickel and rare metals.
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NewsSingle hepatitis E mutation renders sofosbuvir therapy ineffective
A single mutation of the hepatitis E virus has been shown to cause treatment with the hepatitis C drug sofosbuvir to become much less effective, according to a study that provides new insights for future drug development.
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NewsDrugs targeting malaria in Mozambique are still effective
The drugs used to treat and prevent malaria in Mozambique are still effective, according to a genomic analysis of drug resistance markers in Plasmodium falciparum, carried out by the Barcelona Institute for Global Health (ISGlobal) and the Manhiça Health Research Center (CISM). Source: CDC/ Dr. Mae Mellvin Photomicrograph ...
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NewsDrug-resistant fungi thriving in the most remote regions of Earth
New research has found that a disease-causing fungus — collected from one of the most remote regions in the world — is resistant to a common antifungal medicine used to treat infections.
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NewsTreatment with enzyme inhibitor can help combat antimicrobial resistance
Researchers have shown that intravenous treatment with MK-3402, a metallo-beta-lactamase inhibitor, can be an effective strategy in fighting antimicrobial resistance.
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NewsScientists discover small RNA that regulates bacterial infection
Researchers have identified the major mechanism behind the transition between chronic and acute P. aeruginosa infections.
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NewsNewborns worldwide dying from sepsis as antibiotics lose their bite
A global observational study involving more than 3,200 newborn babies suffering from sepsis in 11 countries has shown that many newborns are dying because the antibiotics used to treat sepsis are losing their effectiveness.
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NewsNovel combination therapy counters antibiotic-resistant Mycobacterium infections
Researchers have discovered a novel therapy by combining two antibiotics, rifaximin and clarithromycin, to treat Mycobacterium abscessus, a non-tuberculous mycobacterium (NTM) that causes chronic lung-related infections.
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NewsGlobal response to antimicrobial resistance ‘insufficient’
Governments around the world must do more to tackle the growing threat of drug-resistant infections, new research suggests.
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NewsPreviously unknown antibiotic resistance widespread among bacteria
A new study shows that bacteria in almost all environments carry resistance genes, with a risk of them spreading and aggravating the problem of bacterial infections that are untreatable with antibiotics.
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NewsDrugs pipeline rife with strategies to combat MRSA
A host of new antimicrobial strategies are in the development pipeline that could provide hope for healthcare sectors battling multi-drug resistant Staphylococcus aureus infections.
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NewsStudy uncovers how Leishmania parasite adapts so quickly to drugs
Scientists probing the parasite’s gene expression regulation during mRNA translation have discovered how it is able to preemptively and quickly adapt and respond to drug treatments.
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NewsStaph mechanism for resistance to last resort drug is uncovered
New research has revealed the mechanism of transcriptional regulation via S-nitrosylation for resistance to last resort drug vancomycin in Staphylococcus aureus.
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NewsAI deployed to find promising antibiotic to fight evasive hospital superbug
Scientists have used artificial intelligence to discover a new antibiotic which could be used to fight a deadly, drug-resistant pathogen that strikes vulnerable hospital patients.
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NewsAI-found drug may combat drug-resistant infections
Scietntists used a machine-learning algorithm to identify a compound that kills Acinetobacter baumannii, a bacterium that lurks in many hospital settings.
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NewsMicroplastics changing gut microbiomes of wild seabirds
An international team of scientists has found evidence that microplastics in the digestive tract of seabirds altered the microbiome of the gut – increasing the presence of pathogens and antibiotic-resistant microbes, while decreasing the beneficial bacteria found in the intestines.
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NewsAnti-microbial nanonets ease inflammation during sepsis
Pharmaceutical scientists have developed multi-functional synthetic peptide nanonets for relieving inflammation caused by bacterial infection. This is achieved by concurrent trapping of bacterial endotoxins and pro-inflammatory cytokines.
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NewsUnusual cellular metabolism in fungi linked to AMR
Scientists have discovered that aberrant cellular metabolism in Candida fungi is linked to drug resistance, potentially opening up new possible pathways to antimetabolite therapies.
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NewsNeglected 80yo antibiotic tackles AMR bacteria
An old antibiotic may provide much-needed protection against multi-drug resistant bacterial infections, according to a new study.