All Antimicrobials articles – Page 5
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News
Innovative antiviral defense with new CRISPR tool
Scientists outline how they have overcome a significant obstacle that has hampered the effectiveness of Cas13d: its restriction to the nucleus of mammalian cells.
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Study describes strategy for inactivation of multidrug-resistant bacteria
Zinc oxide nanoparticles with varying morphologies were tested against microorganisms isolated from patients.
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A combination of approved drugs enhances the delivery of anti-bacterial medications to treat tuberculosis
Scientists repurposed approved drugs that they originally tested to normalize blood vessels surrounding tumors to improve drug delivery to cancer cells.
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Silicon spikes skewer 96% of virus particles
An international research team has designed and manufactured a virus-killing surface that could help control disease spread in hospitals, labs and other high-risk environments.
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Maleimide derivative shows promise for treating clinical candidiasis
A new study demonstrates the efficacy of a novel maleimide analogue as a novel antifungal compound, highlighting its potential as a promising option for the treatment of clinical candidiasis.
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Breakthrough antibiotic shows promise against obstinate mycobacterial infections
Researchers assemble a new antibiotic candidate, COE-PNH2, offering a more effective therapeutic option against hard-to-treat mycobacterial lung diseases.
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Landmark NHS deal gives patients access to groundbreaking light-activated antimicrobial to combat antimicrobial resistance
A new light-activated antimicrobial that kills all types of bugs – viruses, bacteria, and fungi – in minutes without generating resistance is being adopted by NHS hospitals to reduce surgical infections.
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Researchers discover evolutionary “tipping point” in fungi
Scientists have found a ‘tipping point’ in the evolution of fungi that throttles their growth and sculpts their shapes, demonstrating how small changes in environmental factors can lead to huge changes in evolutionary outcomes.
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African catfish skin mucus yields promising antibacterial compound
Scientists report they have extracted a compound with powerful antibacterial properties from the skin of farmed African catfish.
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Membrane-producing enzyme offers promising target
The enzyme LpxC, which catalyzes the first irreversible step in the biosynthesis of the outer membrane of Gram-negative bacteria, is a highly promising target for the development of antibiotics.
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Researchers open new leads in anti-HIV drug development, using a compound found in nature
Researchers have successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
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Refrigerate lettuce to reduce risk of E. coli contamination, researchers say
Leafy green vegetables are important sources of dietary fiber and nutrients, but they can harbor harmful pathogens. In particular, lettuce has often been involved in outbreaks of foodborne illness across the U.S. A new study from the University of Illinois Urbana-Champaign examines factors that affect E. coli ...
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Scientists engineer a coating for disease-free produce
A new wax coating technology bolsters the safety of fresh produce and provides enhanced protection against bacteria and fungi. This composite coating provides both immediate and delayed antibacterial effects, according to the article.
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CARB-X funds Visby Medical to develop a portable rapid diagnostic for gonorrhea
Visby Medical aims to improve patients’ health outcomes and increase the lifespan of the last remaining antibiotic for resistant gonorrhea.
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Flu virus variants resistant to new antiviral drug candidate lose pathogenicity, study finds
Influenza A viruses with induced resistance to a new candidate antiviral drug were found to be impaired in cell culture and weakened in animals, a new study has found.
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Mussel-inspired antimicrobial coating protects sanitary fabrics from infections
Researchers have developed a material to fight against the spread of pathogens, infections and antimicrobial resistance. Inspired by the substances secreted by mussels to adhere to rocks, it can be used as a coating to protect healthcare fabrics.
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Green alternative for treating Streptococcus iniae bacteria in hybrid striped bass
Scientists at the United States Department of Agriculture (USDA)’s Agricultural Research Service (ARS) have developed a green antibiotic alternative to treat the deadly pathogen Streptococcus iniae in hybrid striped bass, the fourth most farmed finfish in the United States, according to a recent study. Source: Matt McEntire, ...
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Fungus yields different pathway to the same pharmaceutically important substance
Researchers analyze a fungal biosynthetic pathway and discover a capable enzyme.
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Viruses can cause multiple myeloma cancer, case study finds, offering hope for treatment
An unusual clinical case has led to the discovery that hepatitis B and C viruses are one of the causes of multiple myeloma, and that eliminating infection with antivirals is often the way to fight this type of cancer.
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Careers
How Tanushree’s AMI prize money helped next gen scientists search out antimicrobials
2022’s winner of AMI’s Basil Jarvis Prize, Tanushree Gupta of AgResearch in New Zealand, used her prize money to fund an internship investigating new antimicrobials. Intern Landry Maquet reveals how his research has been going.