All Antimicrobials articles – Page 2
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NewsMicroalgae remove antibiotic residues from wastewater, reducing environmental contamination
In the laboratory, the species Monoraphidium contortum removed some of the drugs added to the liquid and produced biomass with potential commercial value.
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NewsNew hope against superbugs: Promising antibiotic candidate discovered
An international team of researchers has discovered saarvienin A, a new type of glycopeptide antibiotic. Their findings introduce a compound with strong activity against highly resistant bacterial strains.
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NewsScientists evaluate in-vitro activity of ceftazidime-avibactam against carbapenem-resistant gram-negative bacteria
Scientists explored the in-vitro activity of ceftazidime-avibactam (CAZ-AVI) in clinical isolates of carbapenem-resistant gram-negative bacteria collected at the outpatient, emergency, and inpatient departments of the Indus Hospital, Karachi.
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NewsScientists ID previously unknown enzymes that can produce potentially antimicrobial agents
Micro-organisms generate potential agents for combating bacteria and fungi. Researchers have identified and optimized enzymes that can specifically generate a certain functional group of these natural substances, expanding the toolkit of potential agents.
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NewsScientists introduce new engineered drug candidate for Mycobacterium abscessus to save lives
Scientists have introduced a promising drug candidate engineered to target a deadly and emerging infection. They took a hyper-detailed look into the problem of Mycobacterium abscessus, and chemically re-engineered a widely-used rifamycin antibiotic.
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NewsUltimate self-sacrifice: Bacteria activate unusual defense to evade viral attack
Scientists discover that the restriction modification system in some bacteria can kill the cell as a last resort if viruses try to thwart it. They trigger their own death using components of the very same systems that the phages were trying to inhibit.
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Long ReadsCould spiritual healing sites be fertile ground for new antibiotics?
Common motifs between Streptomyces and sites of spiritual healing may help with the discovery of new sites for bioprospecting. Although there may be a temptation to dismiss the spiritual nature of the healing sites, it is important that researchers begin to understand these in the appropriate cultural and spiritual context.
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NewsBarriers remain to peptide-based therapies - but there are answers, reveals study
Peptide-based therapies offer the potential to transform how we treat a range of conditions - but have yet to be adopted for widespread clinical use. A new review uncovers the barriers to adoption and identifies ways to overcome these limitations.
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NewsNew AI technique can uncover antiviral compounds using limited data
Artificial intelligence algorithms have been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease.
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NewsFungi dwelling on human skin may provide new antibiotics
Researchers have uncovered a molecule produced by yeast living on human skin that showed potent antimicrobial properties against a pathogen responsible for a half-million hospitalizations annually in the United States.
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FeaturesMarine-derived antibiotics: can ocean microbes help combat superbugs?
The deep expanse of the Earth’s mysterious marine habitat is teeming with opportunities for scientific discovery, including solutions to the world’s most pressing health crises. Among its rich biodiversity are tiny microbes with tremendous potential.
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NewsSingapore launches national standard to validate antimicrobial disinfectant products
SS 705 provides a first-of-its-kind Singapore-developed assessment to test the effectiveness of antibacterial, antifungal and antiviral potency, as well as durability of surface disinfectants and coatings.
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NewsScientists unlock frogs’ antibacterial secrets to combat superbugs
Researchers exploited natural peptides derived from frogs and improved their structural designs as antibiotic candidates, which are effective against complex mock bacterial communities of drug-resistant pathogens in preclinical tests, sparing beneficial microbiota and human cells.
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NewsResearchers achieve de novo biosynthesis of plant lignans using synthetic yeast consortia
Researchers have achieved the biosynthesis of the antiviral ingredient lignan glycoside in yeast Saccharomyces cerevisiae. By mimicking the spatial and temporal regulation of plant biosynthesis, they designed a system with obligated mutualism, enabling metabolic division of labor among different yeast strains.
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NewsSelective G6PDH inactivation for Helicobacter pylori eradication with transformed polysulfide
A new study highlights a novel mechanism of action driven by polysulfides, presenting a promising alternative strategy for combating H. pylori infections.
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NewsNature’s warriors: How rice plants detect and defend against viral invaders
A groundbreaking study uncovers a molecular mechanism by which rice cells perceive viral infections and initiate antiviral response, which significantly contributes to understanding of virus-host interactions for further disease resistance breeding.
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NewsJapanese plant Daphne pseudomezereum yields anti-HIV daphnane diterpenoids
Scientists have discovered for the first time that Daphne pseudomezereum (commonly known as Onishibari) contains a substance inhibiting replication of human immunodeficiency virus (HIV).
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NewsCurrent antivirals likely less effective against severe infection caused by bird flu virus in cows’ milk
Scientists found that in a preclinical model, two FDA–approved flu antivirals generally did not successfully treat severe H5N1 infections. Meanwhile, the route of infection, whether through the eye, the nose or the mouth, significantly impacts effectiveness.
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NewsPromising new research shows potential to cure recurrent urinary tract infectionsed
Researchers examine the effectiveness of nanogel as a drug delivery system to direct antibiotics into targeted infected cells to improve UTI treatment.
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NewsClove oil yields new Pickering emulsion formulation with enhanced antibacterial properties
Researchers developed a sustainable Pickering emulsion using carbon quantum dots (CQDs), promising solid particles for food applications, derived from clove essential oil residue. They found that CQDs with 40% ethanol demonstrated the highest emulsifying efficacy.