All Antimicrobials articles – Page 4
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News
Symbiosis between bacteria and toxic bird yields discovery of new antimicrobials
A research team has identified two new classes of active substances with antimicrobial properties from bacteria that live in symbiosis with a toxic bird.
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Biopolymers can be harnessed to develop sustainable antibacterial solutions
A new study presents a comprehensive analysis of how naturally abundant biopolymers can be harnessed to develop sustainable antibacterial solutions.
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Researchers push ambitious 1–10–100 unifying goals on antimicrobial resistance ahead of crucial UN meeting
Researchers have shared their goals of using a One Health-approach to save 10 million lives and aim for 100 per cent sustainable access to effective antimicrobials in a new policy paper ahead of a UN high-level meeting in New York later this month.
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Researchers uncover new infection-fighting molecules through ‘molecular de-extinction’
A new study has uncovered sequences for ancient antimicrobial agents in the genomic data of extinct species, offering new hope for the development of antibacterial, antifungal, and antiviral treatments.
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Protect your teeth with fruit and coconut: antimicrobial effects found in biomass compounds
To find an antibacterial that is easy to use and effective in preventing periodontal disease at all ages, researchers verified the antibacterial effect of seven different compounds against the periodontal pathogenic bacteria, Porphyromonas gingivalis.
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Disease X is a threat to free societies - so pandemic preparedness is vital this time round
The Covid-19 pandemic uncovered fracture lines in society that have the potential to destabilize free societies by internal and external groups using misinformation on social media, a new review warns.
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Activated bamboo charcoal’s slow-release properties for enhanced anti-acne formulations containing bamboo vinegar
Bamboo vinegar is a concentrated liquid obtained from bamboo under high temperature and anaerobic conditions. It contains more than 200 organic components, including organic acids, phenols, ketones, alcohols, and esters, among which acetic acid is the main component. Although bamboo vinegar has been approved by the China ...
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New study looks at drug exposures of COVID-19 therapy for pregnant women
A new study provides important insights into the pharmacokinetics and safety of intravenous remdesivir in treating the SARS-CoV-2 coronavirus in pregnant women.
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Infected bacteria fight back with ‘hidden’ genes that halt cell growth, slow viral spread
Researchers have uncovered a surprising way bacteria defend themselves: when a bacterium is infected, bacterial enzymes that copy genetic information from RNA into DNA synthesize genes whose protein products help shut down cell growth.
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Super cally molecules take down tuberculosis
Researchers have identified and synthesised a group of molecules that can act against the cause of tuberculosis in a new way. The callyaerins act against TB by employing a fundamentally different mechanism compared to antibiotic agents used to date.
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New compound found to be effective against flesh-eating bacteria
Researchers have developed a novel compound that effectively clears bacterial infections in mice, including those that can result in rare but potentially fatal ‘flesh-eating’ illnesses, and could be the first of an entirely new class of antibiotics.
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Human clinical study launched using phage lysin to eliminate staph in the nasal microbiome
A “first-in-human” study with the novel drug candidate HY-133 began on 10 July with the recruitment of clinically healthy volunteers who tested positive for Staphylococcus aureus colonisation of the nose.
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Copper oxide nanoparticles to counter pathogens are synthesized from mango
Researchers have synthesized green copper oxide nanoparticles from Mangifera indica leaf extract. They showed potent activity against gram-positive and negative bacteria, as well as fungicidal effects on persimmon fruit pathogens.
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Harnessing big data helps scientists hone in on new antimicrobials
Scientists have detailed a new method of identifying antimicrobial enzymes from large datasets of bacterial proteins, which could provide a solution to antibiotic resistance.
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Careers
Drug discovery and a valuable chance to network: Ugochukwu Anieto on a fascinating experience at ASM 2024
Professor Ugochukwu Anieto of Texas A&M University reveals how AMI’s Scientific Event Travel Grant helped him to gather some fascinating insights on antimicrobial compounds at the recent ASM conference.
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Careers
Connecting with microbiologists and presenting research: Oluwole Owoyemi reports back from ASM 2024
Medical microbiologist Oluwole Owoyemi of Achievers University Owo and Federal University of Technology, Akure, reports back from ASM MICROBE 2024 after being awarded a Scientific Event Travel Grant by Applied Microbiology International.
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Treatment with a mixture of antimicrobial peptides can impede antibiotic resistance
A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for new antibiotic treatments.
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Marine natural product derivative offers new therapeutic strategy to inhibit enterovirus A71 replication
Researchers revealed that the inhibition of enterovirus A71 (EV-A71) replication can be achieved by targeting the human coatomer subunit zeta-1 (COPZ1) using a marine natural product derivative known as MPA-CF3.
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SKAN Research Trust and Quadram Institute Bioscience to develop novel microbial therapies
SKAN Research Trust and Quadram Institute Bioscience will apply the TraDIS-Xpress platform to study the action of traditional medical compounds on bacteria, aiding in the reformulation and development of novel antibacterial regimens.
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WHO releases report on state of development of antibacterials
Although the number of antibacterial agents in the clinical pipeline increased from 80 in 2021 to 97 in 2023, there is a pressing need for innovative agents for serious infections and to replace those becoming ineffective due to widespread use, the WHO says.