All Antimicrobials articles – Page 8
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NewsNew compound found to be effective against flesh-eating bacteria
Researchers have developed a novel compound that effectively clears bacterial infections in mice, including those that can result in rare but potentially fatal ‘flesh-eating’ illnesses, and could be the first of an entirely new class of antibiotics.
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NewsHuman clinical study launched using phage lysin to eliminate staph in the nasal microbiome
A “first-in-human” study with the novel drug candidate HY-133 began on 10 July with the recruitment of clinically healthy volunteers who tested positive for Staphylococcus aureus colonisation of the nose.
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NewsCopper oxide nanoparticles to counter pathogens are synthesized from mango
Researchers have synthesized green copper oxide nanoparticles from Mangifera indica leaf extract. They showed potent activity against gram-positive and negative bacteria, as well as fungicidal effects on persimmon fruit pathogens.
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NewsHarnessing big data helps scientists hone in on new antimicrobials
Scientists have detailed a new method of identifying antimicrobial enzymes from large datasets of bacterial proteins, which could provide a solution to antibiotic resistance.
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CareersDrug discovery and a valuable chance to network: Ugochukwu Anieto on a fascinating experience at ASM 2024
Professor Ugochukwu Anieto of Texas A&M University reveals how AMI’s Scientific Event Travel Grant helped him to gather some fascinating insights on antimicrobial compounds at the recent ASM conference.
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CareersConnecting with microbiologists and presenting research: Oluwole Owoyemi reports back from ASM 2024
Medical microbiologist Oluwole Owoyemi of Achievers University Owo and Federal University of Technology, Akure, reports back from ASM MICROBE 2024 after being awarded a Scientific Event Travel Grant by Applied Microbiology International.
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NewsTreatment with a mixture of antimicrobial peptides can impede antibiotic resistance
A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for new antibiotic treatments.
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NewsMarine natural product derivative offers new therapeutic strategy to inhibit enterovirus A71 replication
Researchers revealed that the inhibition of enterovirus A71 (EV-A71) replication can be achieved by targeting the human coatomer subunit zeta-1 (COPZ1) using a marine natural product derivative known as MPA-CF3.
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NewsSKAN Research Trust and Quadram Institute Bioscience to develop novel microbial therapies
SKAN Research Trust and Quadram Institute Bioscience will apply the TraDIS-Xpress platform to study the action of traditional medical compounds on bacteria, aiding in the reformulation and development of novel antibacterial regimens.
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NewsWHO releases report on state of development of antibacterials
Although the number of antibacterial agents in the clinical pipeline increased from 80 in 2021 to 97 in 2023, there is a pressing need for innovative agents for serious infections and to replace those becoming ineffective due to widespread use, the WHO says.
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NewsWooden surfaces may have natural antiviral properties - and the species matters
Wood has natural antiviral properties that can reduce the time viruses persist on its surface — and some species of wood are more effective than others at reducing infectivity.
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NewsInnovative phage lysin HY-133 enters phase I clinical study
HYpharm’s innovative preventive agent HY-133 has reached the first clinical trial phase. HY-133 is specifically effective against Staphylococcus aureus including multi-resistant strains and is intended to combat its colonisation in the nose.
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NewsUncovering the potential of ‘golden flower’ and its fermentation application in tea
A new review examines the biological characteristics and fermentation applications of Eurotium cristatum, commonly known as the ’golden flower’, a dominant microbial strain in the fermentation process of Fu brick tea.
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NewsWater-soluble version of bacterial enzyme may help researchers develop new antibiotics
Researchers created a water-soluble version of an important bacterial enzyme, which can now be used in drug screens to identify new antibiotics.
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NewsNovel lipopeptide produced by bacterium proves lethal against Staphylococcus aureus
A novel antibacterial lipopeptide produced by the bacterium Serratia marcescens has been shown to be highly effective in killing Staphylococcus aureus – one of the most important pathogens occurring in humans.
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NewsWorld famous Roman Baths could help scientists counter antibiotic resistance
The world-famous Roman Baths are home to a diverse range of microorganisms which could be critical in the global fight against antimicrobial resistance, a new study suggests.
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NewsNewly isolated antibodies may aid effort to fight influenza B
Researchers have isolated human monoclonal antibodies against influenza B, a significant public health threat that disproportionately affects children, the elderly and other immunocompromised individuals.
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NewsThe world’s most powerful anti-fungal chemistries cause fungal pathogens to self-destruct
Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.
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NewsAntibacterial protein offers new therapeutic target against pancreatic cancer
A recent study describes how pancreatic cancer stem cells take advantage of an antibacterial protein, PGLYRP1, to evade the immune system and protect themselves from early elimination.
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NewsThe effect of combinations of antibiotics and natural products on antimicrobial resistance
Thymol, rosemary oil, curcumin, capsicum, and moringa seed extract showed the highest synergistic activity with tested antibiotics against two key pathogens, a new study shows.