All artemisinin articles
-
NewsChemical trick could turn losing malaria drug into a winner
A new generation of malaria drugs failed clinical trials, in part because they were hard to swallow. Chemists have remodeled their structures to make them more soluble, while maintaining their effectiveness against drug-resistant parasites.
-
NewsStudy uncovers first evidence of resistance to standard malaria treatment in African children with severe malaria
Researchers have uncovered evidence of partial resistance to artemisinin derivatives — the primary treatment for malaria — in young children with severe, or ’complicated’ malaria.
-
NewsStudy provides first evidence of African children with severe malaria experiencing partial resistance to world’s most powerful malaria drug
A new study from Uganda provides the first evidence to date that resistance to a lifesaving malaria drug may be emerging in the group of patients that accounts for most of the world’s malaria deaths: young African children suffering from serious infections.
-
NewsNew agent effective against drug-resistant malaria parasites
Scientists have developed a promising new antimalarial agent, DIF-1(+3), which is a derivative of Dictyostelium differentiation-inducing factor-1 (DIF-1).
-
NewsBreakthrough research identifies mechanism behind drug resistance in malaria parasite
A new study has found that a cellular process called transfer Ribonucleic acid (tRNA) modification influences the malaria parasite’s ability to develop resistance to Artemisinin-based combination therapies.
-
NewsResearchers develop new approaches in the fight against drug resistance in malaria
Researchers have combined the anti-malaria drug artemisinin with coumarin, which, like artemisinin, is also found in plants, and developed an auto-fluorescent compound from both bioactive substances.
-
NewsMainstay malaria drug may be beginning to fail in the Horn of Africa
In eastern Africa, malaria parasites have developed resistance to artemisinins, the backbone of current treatment regimens, a development that could dramatically worsen malaria’s impact if partner drugs fail in the future.
-
NewsMalaria parasites resistant to treatment and detection emerge in Ethiopia
Genomic surveillance by scientists has revealed mutations in malaria-causing parasites that will complicate efforts to eradicate the disease in Africa.
-
NewsDrugs targeting malaria in Mozambique are still effective
The drugs used to treat and prevent malaria in Mozambique are still effective, according to a genomic analysis of drug resistance markers in Plasmodium falciparum, carried out by the Barcelona Institute for Global Health (ISGlobal) and the Manhiça Health Research Center (CISM). Source: CDC/ Dr. Mae Mellvin Photomicrograph ...