All capsid articles
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NewsEnhanced inner ear tropism of Adeno-Associated Virus (AAV) vectors via peptide display on AAV1 capsid
Researchers improving efficiacy of AAV)-mediated gene therapy for the inner ear screened and inserted short peptide motifs onto the surface of the AAV1 capsid. These engineered vectors achieved markedly higher transduction rates in inner ear hair cells and supporting cells.
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NewsScientists win award for bringing breakthrough HIV treatment lenacapavir into play
Three people have been awarded the AAAS Mani L. Bhaumik Breakthrough of the Year Award for their work on the first HIV drug to offer long-lasting protection from infection — eliminating the need for people to take a daily pill.
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NewsSimulations show how HIV sneaks into the nucleus of the cell
A new study has revealed how HIV squirms its way into the nucleus as it invades a cell.
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NewsHIV ‘secret handshake’ helps it reach cell’s centre to kickstart infection
New research reveals how the HIV capsid gets into the nuclear pore barrier channel.
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NewsGene-delivering viruses cross into brain in step toward gene therapy for neurological diseases
A family of adeno-associated viruses (AAVs) has been developed that are capable of delivering gene therapies to the brain, a particularly challenging target tissue.